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The Gautrot Lab: Biointerfaces for Life Sciences

Publications

Title

Impact of the multiscale viscoelasticity of quasi-2D self-assembled protein networks on stem cell expansion at liquid interfaces

https://www-sciencedirect-com.ezproxy.library.qmul.ac.uk/science/article/pii/S0142961222001338
Kong, D.; Peng, L.; Bosch-Fortea, M.; Chrysanthou, A.; Alexis, C.V.J.-M.; Matellan, C.; Zarbakhsh, A.; Mastroianni, G.; del Rio Hernandez, A.; Gautrot, J.E.. Biomaterials, 2022, 121494.

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Protein Ligand Nanopattern Size Selects for Cellular Adhesion via Hemidesmosomes over Focal Adhesions

Ghorbani, S.; Shahrokhtash, A.; Gautrot, J.E.; Sutherland, D.S.
Small Methods. https://onlinelibrary.wiley.com/doi/10.1002/smtd.202200152

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Ultrafast Photo-Crosslinking of Thiol-Norbornene Opaque Silicone Elastomer Nanocomposites in Air

Nguyen, K.D.Q.; Crespo-Ribadeneyra, M.; Picot, O.; Colak, B.; Gautrot, J.E.
ACS Appl. Polym. Mater. . 2021, 3 (11), 5373-5385

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Novel Crosslinking System for Poly-Chloroprene Rubber to Enable Recyclability and Introduce Self-Healing

Kaur, A.; Gautrot, J.E.; Cavalli, G.; Watson, D.; Bickley, A.; Akutagawa, K.; Busfield, J.J.C.
Polymers . 2021, 13 (19), 3347

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Nanoengineered electrospun fibers and their biomedical applications: a review

Zhang, X.; Shi, X.T.; Gautrot, J.E.; Peijs, T.
Nanocomposites. 2021, 7, 1-34

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Engineered Cell-Degradable Poly(2-alkyl-2-oxazoline) Hydrogel for Epicardial Placement of Mesenchymal Stem Cells for Myocardial Repair

You, Y.; Kobayashi, K.; Colak, B.; Luo, P.; Cozens, E.; Fields, L.; Suzuki, K.; Gautrot, J.E.
Biomaterials. 2021, 269, 120356

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Responsive Polymer Brush Design and Emerging Applications for Nanotheranostics

Li, D.; Xu, Z.; Want, J.; Gautrot, J.E.
Advanced Healthcare Mater.. 2021, 10, 2000953.

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Photo-Configurable, Cell-Remodelable Disulfide Crosslinked Hyaluronic Acid Hydrogels

Wu, L.; Di Cio, S.; Azevedo, H.; Gautrot, J.E.
Biomacromolecules . 2020, 21 (12), 4663–4672

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Contractile myosin rings and cofilin-mediated actin disassembly orchestrate ECM nanotopography sensing

Di Cio, S.; Iskratsch, T.; Connelly, J.T.; Gautrot, J.E.
Biomaterials. 2020, 232, 119683

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Core-independent approach for polymer brush-functionalised nanomaterials with a fluorescent tag for RNA delivery

Li, D.; Wu, L.; Qu, F. ; Ribadeneyra, M.C.; Tu, G.; Gautrot, J. E.
Chem. Commun.. 2019, 55 (94), 14166-14169

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Peptide Cross-Linked Poly(2-oxazoline) as a Sensor Material for the Detection of Proteases with a Quartz Crystal Microbalance

Ahmad, N.; Colak, B.; Gibbs, M.J.; Zhang, D.-W.; Gautrot, J.E.; Watkinson, M.; Becer, C.R. and Krause, S.
Biomacromolecules . 2019, 20 (7), 2506-2514

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Modes of adsorption of polyelectrolytes to model substrates of hydroxyapatite

Hakobyan, S.; Roohpour, N.; Gautrot, J.E.
J. Coll. Interface Sci. . 2019, 543, 237-246

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A Kinetic Model of Oligonucleotide-Brush Interactions for the Rational Design of Gene Delivery Vectors

Qu, F.; Li, D.; Ma, X.; Chen, F. and Gautrot, J.E.
Biomacromolecules . 2019, 20 (6), 2218-2229

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A Photoaddressable Liquid Crystalline Phase Transition in Graphene Oxide Nanocomposites

Crespo, M.; Santagiuliana, G.; Picot, O.; Portale, G.; Bilotti, E.; Gautrot, J.E.
Adv. Funct. Mater.. 2019, 29 (24), 1900738

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Peptide Cross-Linked Poly (Ethylene Glycol) Hydrogel Films as Biosensor Coatings for the Detection of Collagenase

Ahmad, N.; Colak, B.; Zhang, D.-W.; Gibbs, M.J.; Watkinson, M.; Becer, C.R.; Gautrot, J.E.; Krause, S.
Sensors . 2019, 19 (7), 1677

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Hydration dependent mechanical performance of denture adhesive hydrogels

Fengfeng, Z.; Ann, Y.; Li, D.; Roohpour, N.; Barber, A.; Gautrot, J.E.
Dental Mater. . 2018, 34 (10), 1440-1448

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Stem Cell Expansion and Fate Decision on Liquid Substrates Are Regulated by Self-Assembled Nanosheets

Kong, D.; Peng, L.; di Cio, S.; Novak, P.; Gautrot, J.E.
ACS Nano. 2018, 12 (9), 9206-9213

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Surface-Initiated Poly(oligo(2-alkyl-2-oxazoline)methacrylate) Brushes

Tang, P.; di Cio, S.; Wang, W.; Gautrot, J.E.
Langmuir. 34, 10019-10027

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Hydrophobic and hydrophilic effects on water structuring and adhesion in denture adhesives

Gill, S.K.; Roohpour, N.; An, Y.R.; Gautrot, J.E.; Topham, P.D.; Tighe, B.J.
J. Biomed. Mat. Res. Part A. 106, 1355-1362

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Protein Nanosheet Mechanics Controls Cell Adhesion and Expansion on Low-Viscosity Liquids

Kong, D.; Megone, W.; Nguyen, K.D.Q.; Di Cio, S.; Ramstedt, M.; Gautrot, J.E.
Nano Letters. 18, 1946-1951

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Cardiomyocytes Sense Matrix Rigidity through a Combination of Muscle and Non-muscle Myosin Contractions

Pandey, P.; Hawkes, W.; Hu, J.Q.; Megone, W.V.; Gautrot, J.; Anilkumar, N.; Zhang, M.; Hirvonen, L.; Cox, S.; Ehler, E.; Hone, J.; Sheetz, M.; Iskratsch, T.
Dev. Cell. 44, 326+

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Design of Polymer Brushes for Cell Culture and Cellular Delivery

Li, D.; Gautrot, J.E.
Polymer and Biopolymer Brushes: for Materials Science and Biotechnology. 20, 557-602

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Solution Conformation of Polymer Brushes Determines Their Interactions with DNA and Transfection Efficiency

Krishnamoorthy, M.; Li, D.Y.; Sharili, A.S.; Gulin-Sarfraz, T.; Rosenholm, J.M.; Gautrot, J.E.
Biomacromolecules. 18, 4121-4132

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The culture of HaCaT cells on liquid substrates is mediated by a mechanically strong liquid-liquid interface

Kong, D.; Nguyen, K.D.Q.; Megone, W.; Peng, L.; Gautrot, J.E.
Faraday Discussions. 204, 367-381

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Physico-chemical characterization of Antheraea mylitta silk mats for wound healing applications

Darshan, G.H.; Kong, D.X.; Gautrot, J.E.; Vootla, S.
Scientific Reports. 7, 10344

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Tunable and processable shape memory composites based on degradable polymers

Zhang, X.; Geven, M.A.; Grijpma, D.W.; Peijs, T.; Gautrot, J.E.
Polymer. 122, 323-331

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Differential integrin expression regulates cell sensing of the matrix nanoscale geometry

Di Cio, S.; Bøggild, T.M.L.; Connelly, J.; Sutherland, D.S.; Gautrot, J.E.
Acta. Biomat.. 50, 280-292

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Adhesive ligand tether length affects the size and length of focal adhesions and influences cell spreading and attachment

Attwood, S.J.;Cortes, E.; Haining, A.W.M.; Robinson, B.; Li, D.; Gautrot, J.; del Río Hernández, A.
Sci. Rep.. 6, 34334

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Impact of the Molecular Environment on ThiolEne Coupling For Biofunctionalization and Conjugation

Colak, B.; Da Silva, J.C.S.; Soares, T.A.; Gautrot, J.E.
Bioconjug. Chem.. 27 (9), 2111-2123.

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Failure mechanisms in denture adhesives

Ann, Y.; Li, D.; Roohpour, N. ; Gautrot, J.E. ; Barber, A.
Dental Mater.. 32 (5), 615-623.

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Polymer-polymer composites for the design of strong and tough degradable biomaterials

Zhang, X; Geven, M.A.; Grijpma, D.W.; Gautrot, J.E.; Peijs, T
Mater. Today Commun.. 8, 52-63.

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Study of thiol–ene chemistry on polymer brushes and application to surface patterning and protein adsorption

Tan, K. Y.; Ramstedt, M.; Colak, B.; Huck, W. T. S.; Gautrot, J.E.
Polym. Chem.. 7, 979-990.

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Conductive surfaces with dynamic switching in response to temperature and salt

Hackett, A. J.; Malmström, J.; Molino, P. J.; Gautrot, J. E.; Zhang, H.; Higgins, M. J.; Wallace, G. G.; Williams, D. E.; Travas-Sejdic, J.
J. Mater. Chem. B. 3, 9285-9294

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The nanoscale geometrical maturation of focal adhesions controls stem cell differentiation and mechanotransduction.

Gautrot, J.E.; Malmstrom, J.; Sundh, M.; Margadant, C.; Sonnenberg, A.; Sutherland, D.S.
Nano Lett.. 14, 3945-3952.

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Biofunctionalization of PEGylated microcapsules for exclusive binding to protein substrates.

Deo, D.I.; Gautrot, J.E.; Sukhorukov, G.B.; Wang, W.
Biomacromolecules. 15, 2555-2562.

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Decoupling geometrical and chemical cues directing epidermal stem cell fate on polymer brush-based cell micro-patterns.

Tan, K.Y.; Lin, H.; Ramstedt, M.; Watt, F.M.; Huck, W.T.S.; Gautrot, J.E.
Integr. Biol.. 5, 899-910.

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The surface charge of anti-bacterial coatings alters motility and biofilm architecture.

Rzhepishevska, O.; Hakobyan, S.; Ruhal, R.; Gautrot, J.E.; Barberoc, D.; Ramstedt, M.
Biomater. Sci.. 1, 589-602.

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Mimicking normal tissue architecture and perturbation in cancer with engineered micro-epidermis.

Gautrot, J.E.; Wang, C.; Liu, X.; Goldie, S.; Trappmann, B.; Huck, W.T.S.; Watt, F.M.
Biomaterials. 33, 5221-5229.

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Extracellular matrix tethering regulates stem cell fate.

Trappmann, B.; Gautrot, J.E.; Connelly, J; Strange, D.G.T.; Li, Y.; Oyen, M.; Cohen Stuart, M.A.; Boehm, H.; Li, B.; Vogel, V.; Spatz, J.P.; Watt, F.M.; Huck, W.T.S.
Nat. Mater.. 11, 642-649.

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Polymer brushes showing non-fouling in blood plasma challenge the currently accepted design of protein resistant surfaces.

Rodriguez-Emmenegger, C.; Brynda, E.; Riedel, T.; Houska, M.; Subr, V.; Alles, A.B.; Hasan, E.; Gautrot, J.E.; Huck, W.T.S.
Macromol. Rapid Commun.. 32, 952-957.

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Recent advances in entropy-driven ring-opening polymerizations.

Strandman, S.; Gautrot, J.E.; Zhu, X.X.
Polymer Chemistry. 2, 791-799.

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Actin and SRF transduce physical cues from the microenvironment to regulate epidermal stem cell fate decisions.

Connelly, J; Gautrot, J.E.; Trappmann, B.; Tan, D.W.M.; Donati, G.; Huck, W.T.S.; Watt, F.M.
Nat. Cell Biol.. 12, 711-U177.

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Exploiting the superior protein resistance of polymer brushes to control single cell adhesion and polarisation at the micron scale.

Gautrot, J.E.; Trappmann, B.; Oceguera-Yanez, F.; Connelly, J.; He, X.;Watt, F.M.; Huck, W.T.S.
Biomaterials. 31, 5030-5041.

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Shape memory properties of main chain bile acids polymers.

Therien-Aubin, H.; Gautrot, J.E.; Zhu, X.X.
Polymer. 51, 22-25.

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Bio-functionalized protein resistant oligo(ethylene glycol)-derived polymer brushes as selective immobilization and sensing platforms.

Trmcic-Cvitas, J.; Hasan, E.; Ramstedt, M; Li, X.; Cooper, M.; Abel, C.; Huck, W.T.S.; Gautrot, J.E.
Biomacromolecules. 10, 2885-2894.

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Synthesis of electron-accepting polymers containing phenanthra-9,10-quinone units.

Gautrot, J.E.; Hodge, P.; Helliwell, M; Raftery, J.; Cupertino, D.
J. Mat. Chem.. 19, 4148-4156.

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2,6-diaryl-9,10-anthraquinones as models for electron-accepting polymers.

Gautrot, J.E.; Hodge, P.; Cupertino, D.; Helliwell, M.
New J. Chem.. 31, 1585-1593.

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Experimental evidence for carbonyl-Pi electron cloud interactions.

Gautrot, J.E.; Hodge, P.; Cupertino, D.; Helliwell, M.
New J. Chem.. 30, 1801-1808.

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Enhancing the photoluminescence intensity of conjugated polycationic polymers by using quantum dots as antiaggregation reagents.

Nguyen, B.T.; Gautrot, J.E.; J, C.; Bunner, P.L.; Nguyen, M.T.; Zhu, X.X.
Langmuir. 22 (10), 4799-803.

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Electrode specific electropolymerization of ethylenedioxythiophene: Injection enhancement in organic transistors.

Schroeder, R.; Majewski, L.A.; Grell, M.; Maunoury, J.; Gautrot, J.E.; Hodge, P.; Turner, M.
App. Phys. Lett.. 87 (11), 113501-3.

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