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MB PhD student profile: Rizwan Hameed

Rizwan Hameed is a Queen Mary MBBS student, currently studying on the MB PhD programme undertaking a research project to gain a PhD. The three-year research degree aims to nurture the development of highly skilled, independent clinical research scientists who can contribute to medical research as part of their clinical career. Rizwan discusses his PhD topic, his experience of the programme so far, and his plans for the future.

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Tell us a bit about your background

I started my medical studies three years ago, here in Whitechapel, and was immediately intrigued by the biomedical research presence in the area. Throughout the initial years I took a keen interest in the basic science underlying the concepts I learnt about on the ward and in the lecture theatre. I spent time beside my studies in the lab learning about research methodology and techniques. Before long the idea took root that this was something I wished to take further, finding the time I spent researching, and in the lab, very rewarding. 

What attracted you to the MB PhD programme at Queen Mary?

The MB PhD programme is a stepping stone towards a career in clinical academics, that is one which combines clinical practice and biomedical research. The three-years of dedicated time to focus on in-depth and high quality research is an unrivalled opportunity to develop a rich and transferrable research skillset, while receiving dedicated support in academic, professional and clinical domains.

There are, of course, other entry points to integrated academic training, but the MB PhD serves as an ideal entry point for those looking to streamline their clinical and academic training, with the intention of pursuing a career in clinical academics.

Tell us about your PhD topic

I study glioblastoma – the most aggressive brain tumour in adults – within Professor Silvia Marino’s lab. I grow cerebral organoids – mini brains to you and me – to which we introduce genetic mutations. Thereafter we analyse the molecular and epigenetic signatures which have developed, using powerful computing software.

The results of these analyses will allow us to better understand the interplay between different genes in the development of glioblastoma, guiding future research, with the overall aim to overcome the tumour’s treatment resistance.

How will the programme benefit you in your career?

MB PhD-trained physicians have the advantage of getting an early foot in the door when it comes to starting their own independent/early career research. In the first instance, this may take the form of an NIHR funded Integrated Academic Training (IAT) opportunity. Subsequently, MB PhDs can competitively apply for further funding, such as MRC or Wellcome Trust clinician scientist fellowships.

I am hoping that I can benefit from these funded opportunities which would allow me to develop both as a medical specialist and a scientist, in the interest of facilitating the best outcomes for my patients.

Do you have any advice for someone considering an MB PhD?

This programme serves as a formative experience in the development of an independent clinical academic. If this aligns with your career prospects, and you have some relevant experience, consider making contact to discuss eligibility, projects and the practicalities.

Professor Cleo Bishop (c.l.bishop@qmul.ac.uk) will happily hear from you, ideally by the start of the third year of your MBBS at the latest – this is not limited to internal Queen Mary students.

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