Dr Ana Muñiz-García, PhD

Profile

Dr Muñiz-García completed a BSc (Hons) in Biotechnology at Universidad de León (Spain) where her final year project consisted of the validation of an organotypic brain slice model for stroke studies (Prof Arsenio Fernández-López lab). She then started her PhD at the University of Liverpool (UK), where she developed studies on extracellular vesicle (EV) release in hypoxia. These focused on the molecular mechanisms behind EV release (Dr Silvia Mora lab), and the potential therapeutic effects of EVs from hypoxia pre-conditioned human umbilical-cord derived mesenchymal stromal cells (hUC-MSCs) (Prof Patricia Murray lab). In 2022 she joined Prof Dean Nižetić’s lab at QMUL where she focuses on the study of Alzheimer’s disease pathology progression and neuronal function in the context of Down Syndrome using 2D and 3D human induced pluripotent stem cell (hiPSC) models.

Research

Publications

Key Publications

Muñiz-García A*, Pichardo AH*, Littlewood J, Tasker S, Sharkey J, Wilm B, Peace H, O'Callaghan D, Green M, Taylor A, Murray A (2023). Near infrared conjugated polymer nanoparticles (CPN™) for tracking cells using fluorescence and optoacoustic imaging. Nanoscale Advances vol. 5, (20) 5520 - 5528.
10.1039/d3na00546a
*Equal contribution

Muñiz-García A, Wilm B, Murray P, Cross MJ (2022). Extracellular Vesicles from Human Umbilical Cord-Derived MSCs Affect Vessel Formation In Vitro and Promote VEGFR2-Mediated Cell Survival. Cells vol. 11, (23)
10.3390/cells11233750

Muñiz-García A, Romero M, Falcόn-Perez JM, Murray P, Zorzano A, Mora S. (2022). Hypoxia-induced HIF1α activation regulates small extracellular vesicle release in human embryonic kidney cells. Scientific Reports vol. 12, 1443.
10.1038/s41598-022-05161-7

All Publications