Profile
Member of the UK Committee on the Medical Effects of Air Pollution (COMEAP)
Elected Secretary of the Paediatric Assembly of the European Respiratory Society
Deputy Director of the Blizard Institute (Clinical)
Member of the International Advisory Board of Thorax
Member of the American Thoracic Society Conference Committee
Summary
Jonathan Grigg is the leading UK paediatrician in the effects of air pollution. His research has identified the mechanisms whereby inhalation of particles increases vulnerability to bacterial infection. These studies have informed the public on the risks of air pollution, and influenced national policy. He was a lead author of the Royal College of Physicians’ Report on the long-term effects of air pollution (https://www.rcplondon.ac.uk/projects/outputs/every-breath-we-take-lifelong-impact-air-pollution ). In the area of paediatric respiratory medicine, he has led major independent and industry trials of new and existing asthma therapies.
Centre: Genomics and Child Health.
Teaching
MBBS course (4th year paediatrics introductory lectures), intercalated BSc project supervision
MSc biomedical sciences/clinical microbiology project supervision
Topics for PhD/MD(Res) supervision: air pollution and asthma/cystic fibrosis, mechanisms of vulnerability to respiratory infections
Research
Research Interests:
Randomised controlled trials of therapies for wheezing diseases in children
Mechanisms for particulate-pollution induced vulnerability to infection
Children's environmental health research
Research Group Members
- Dr Lisa Miyashita, Postdoctoral Research Assistant
Publications
Oliver AJ, Covar RA, Goldfrad CH et al. (2016). Randomised trial of once-daily vilanterol in children with asthma on inhaled corticosteroid therapy. Respiratory Research vol. 17, (1)
Walton RT, Mudway IS, Dundas I et al. (2016). Air pollution, ethnicity and telomere length in east London schoolchildren: An observational study. Environ Int vol. 96, 41-47.
Costello RW, Foster JM, Grigg J et al. (2016). The Seven Stages of Man: The Role of Developmental Stage on Medication Adherence in Respiratory Diseases. J Allergy Clin Immunol Pract vol. 4, (5) 813-820.
Price DB, Colice G, Israel E et al. (2016). Add-on LABA in a separate inhaler as asthma step-up therapy versus increased dose of ICS or ICS/LABA combination inhaler. ERS Monograph vol. 2, (2)
Grigg J (2016) . Seeking an Accurate, Point-of-Contact Diagnostic Test for Bacterial Pneumonia. Am J Respir Crit Care Med vol. 193, (4) 353-355.
Suri R, Periselneris J, Lanone S et al. (2016). Exposure to welding fumes and lower airway infection with Streptococcus pneumoniae. J Allergy Clin Immunol vol. 137, (2) 527-534.e7.
Grigg J (2016). Suppression of lung growth by environmental toxins. Thorax vol. 71, (2) 99-100.
Grigg J (2016). Antibiotics for preschool wheeze. Lancet Respir Med vol. 4, (1) 2-3.
View all Jonathan Grigg's Research Publications at: http://www.researchpublications.qmul.ac.uk
Supervision
Abigail Whitehouse, Clinical Research Fellow/PhD student
Norrice Liu, Clinical Research Fellow/PhD student
Lee Koh, PhD student
Victoria Oyenuga, PhD Student
