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Critical Care and Peri-operative Medicine Research Group

MSc Students Publications

Please see below the publications from our MSc students who are associated with the Critical Care and Perioperative Medicine Research Group:

  1. Janssen H, Jhanji S, Oliver NS, Ackland GL; GlucoVITAL Investigators. Ward monitoring 4.0: real-time metabolic insights from continuous glucose monitoring into perioperative organ dysfunction. Br J Anaesth. 2024 May;132(5):843-848.
  2. Ackland GL, Patel A, Abbott TEF, Begum S, Dias P, Crane DR, Somanath S, Middleditch A, Cleland S, Gutierrez Del Arroyo A, Brealey D, Pearse RM; Stopping Perioperative ACE-inhibitors or angiotensin-II receptor blockers (SPACE) trial investigators. Discontinuation vs. continuation of renin-angiotensin system inhibition before non-cardiac surgery: the SPACE trial. Eur Heart J. 2024 Apr 1;45(13):1146-1155
  3. Chadda KR, Blakey EE, Davies TW, Puthucheary Z. Risk factors, biomarkers, and mechanisms for persistent inflammation, immunosuppression, and catabolism syndrome (PICS): a systematic review and meta-analysis. Br J Anaesth. 2024 Apr 29:S0007-0912(24)00201-0. doi: 10.1016/j.bja.2024.03.038. Epub ahead of print. PMID: 38688799.
  4. Chadda KR, Puthucheary Z. Persistent inflammation, immunosuppression, and catabolism syndrome (PICS): a review of definitions, potential therapies, and research priorities. Br J Anaesth. 2024 Mar;132(3):507-518. doi: 10.1016/j.bja.2023.11.052. Epub 2024 Jan 4. PMID: 38177003; PMCID: PMC10870139.
  5. Ackland GL, Martin T, Joseph M, Dias P, Hameed R, Gutierrez Del Arroyo A, Hewson R, Abbott TEF, Spooner O, Bhogal P. Transauricular nerve stimulation in acute ischaemic stroke requiring mechanical thrombectomy: Protocol for a phase 2A, proof-of-concept, sham-controlled randomised trial. PLoS One. 2023 Dec 22;18(12):e0289719. 
  6. James A, Bruce D, Tetlow N, Patel ABU, Black E, Whitehead N, Ratcliff A, Jamie Humphreys A, MacDonald N, McDonnell G, Raobaikady R, Thirugnanasambanthar J, Ravindran JI, Whitehead N, Minto G, Abbott TEF, Jhanji S, Milliken D, Ackland GL. Heart rate recovery after orthostatic challenge and cardiopulmonary exercise testing in older individuals: prospective multicentre observational cohort study. BJA Open. 2023 Nov 3;8:100238. 
  7. Haines RW, Fowler AJ, Liang K, Pearse RM, Larsson AO, Puthucheary Z, Prowle JR. Comparison of Cystatin C and Creatinine in the Assessment of Measured Kidney Function during Critical Illness. Clin J Am Soc Nephrol. 2023 Aug 1;18(8):997-1005. doi: 10.2215/CJN.0000000000000203. Epub 2023 May 31. PMID: 37256861; PMCID: PMC10564373.
  8. Patel ABU, Bibawy PPWM, Althonayan JIM, Majeed Z, Gan WL, Abbott TEF, Ackland GL. Effect of transauricular nerve stimulation on perioperative pain: a single-blind, analyser-masked, randomised controlled trial. Br J Anaesth. 2023 Apr;130(4):468-476. 
  9. McNelly A, Langan A, Bear DE, Page A, Martin T, Seidu F, Santos F, Rooney K, Liang K, Heales SJ, Baldwin T, Alldritt I, Crossland H, Atherton PJ, Wilkinson D, Montgomery H, Prowle J, Pearse R, Eaton S, Puthucheary ZA. A pilot study of alternative substrates in the critically Ill subject using a ketogenic feed. Nat Commun. 2023 Dec 15;14(1):8345. doi: 10.1038/s41467-023-42659-8. PMID: 38102152; PMCID: PMC10724188.
  10. Patel ABU, Bibawy PPWM, Majeed Z, Gan WL, Ackland GL. Trans-auricular vagus nerve stimulation to reduce perioperative pain and morbidity: protocol for a single-blind analyser-masked randomised controlled trial. BJA Open. 2022 Jun;2:
  11. Walker SLM, Muthoo C, Sanchez J, Del Arroyo AG, Ackland GL. Sex-specific differences in cardiac function, inflammation and injury during early polymicrobial sepsis. Intensive Care Med Exp. 2022 Jun 20;10(1):27. 
  12. Ali A, Weber V, Thompson SJ, Abbott TEF, Harmston R, David AL, Ackland GL; EPIFEVER-2 investigators. IL-1ra polymorphisms and risk of epidural-related maternal fever (EPIFEVER-2): study protocol for a multicentre, observational mechanistic cohort study. Int J Obstet Anesth. 2022 May;50:103540
  13. Jones TF, Iakovou D, Makariou N, Fowler AJ, Ackland GL. Metformin and mortality after surgery: a systematic review and meta-analysis. Br J Anaesth. 2022 Apr;128(4):e277-e279. 
  14. May SM, Chiang E, Reyes A, Martir G, Patel A, Karmali S, Patel S, West S, Del Arroyo AG, Gourine AV, Ackland GL. Neuromodulation of innate immunity by remote ischaemic conditioning in humans: Experimental cross-over study. Brain Behav Immun Health. 2021 Jul 15;16:100299. 
  15. Heywood WE, Bliss E, Bahelil F, Cyrus T, Crescente M, Jones T, Iqbal S, Paredes LG, Toner AJ, Del Arroyo AG, O'Toole EA, Mills K, Ackland GL. Proteomic signatures for perioperative oxygen delivery in skin after major elective surgery: mechanistic sub-study of a randomised controlled trial. Br J Anaesth. 2021 Oct;127(4):511-520 
  16. May SM, Reyes A, Martir G, Reynolds J, Paredes LG, Karmali S, Stephens RCM, Brealey D, Ackland GL. Acquired loss of cardiac vagal activity is associated with myocardial injury in patients undergoing noncardiac surgery: prospective observational mechanistic cohort study. Br J Anaesth. 2019 Dec;123(6):758-767. 
  17. Ackland GL, Abbott TEF, Minto G, Clark M, Owen T, Prabhu P, May SM, Reynolds JA, Cuthbertson BH, Wijeysundera D, Pearse RM; METS and POM-HR Study Investigators. Heart rate recovery and morbidity after noncardiac surgery: Planned secondary analysis of two prospective, multi-centre, blinded observational studies. PLoS One. 2019 Aug 21;14(8):e0221277.
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