Alterations in autonomic control are pathognomonic after injury and systemic inflammation, but our understanding of why these occur and whether they can be manipulated to change clinical outcome is in its’ translational infancy. Restoring, or preserving, autonomic function may help protect organ function, in part through maintaining exercise capacity and/or limiting systemic inflammation.
Autonomic pathways pivotal in the perioperative stress response
Inflammatory mechanism underpinning epidural-related maternal fever