The Stojic lab studies RNA-mediated mechanisms controlling cell division and how dysregulation of these processes leads to genome instability and cancer. We are particularly focused on the role of long noncoding RNAs (lncRNAs) and how changes in lncRNA activities contribute to cancer.
Dodel M, Guiducci G, Dermit M, Krishnamurthy S, Award EL, Capraro F, Rekad Z, Stojic L, Mardakheh FK (2024) “TREX reveals proteins that bind to specific RNA regions in living cells”, Nature Methods, 21:423 (PMID: 38374261)
Guiducci G, Stojic L (2021) "Long Noncoding RNAs at the Crossroads of Cell Cycle and Genome Integrity", Trends in Genetics, 37:528 (PMID: 33685661)
Stojic L, Lun ATL, Mascalchi P, Ernst C, Redmond AM, Mangei J, Barr A, Bousgouni V, Bakal C, Marioni JC, Odom DT, Gergely F (2020) "A high-content RNAi screen reveals multiple roles for long noncoding RNAs in cell division", Nature Communications, 11:1851 (PMID: 32296040)
Stojic L, Lun ATL, Mangei J, Mascalchi P, Quarantotti V, Barr A, Bakal C, Marioni JC, Gergely F, Odom DT (2018) "Specificity of RNAi, LNA and CRISPRi as loss-of-function methods in transcriptional analysis", Nucleic Acids Res, 46:5950 (PMID: 29860520)