Professor Richard Hooper

Profile

I joined QMUL in 2010 having worked previously as a biostatistician at Cambridge University, King’s College London, Imperial College London, and also for a short time with the Government Statistical Service in the Department of Health. I am Professor of Medical Statistics and Deputy Centre Lead at the Centre for Evaluation & Methods, and Lead of the Methodology Research Unit, as well as Institutional Co-Lead at QMUL for the NIHR Research Support Service (RSS) Hub at Imperial College London & Partners. In 2019 I was awarded a Senior Fellowship with The Healthcare Improvement Studies (THIS) Institute, and am now a member of their alumni community.

Research

Research Interests:

My research programme is aimed at driving innovation in the design of randomised evaluations of health interventions and quality improvement programmes, including stepped wedge trials and other novel approaches to clustered trials. To find out more about stepped wedge trials visit my Stepped Wedgehog website. My work has appeared in the BMJ, the International Journal of Epidemiology, the Journal of Clinical Epidemiology, Statistics in Medicine, and Statistical Methods in Medical Research. I have given invited talks at international conferences of the International Society for Clinical Biostatistics, Royal Statistical Society, and Society for Clinical Trials.

Publications

• McKenzie JE, Taljaard M, Hemming K et al. (2025). Reporting of cluster randomised crossover trials: extension of the CONSORT 2010 statement with explanation and elaboration..

  
  

  DOI: 10.1136/bmj-2024-080472

  
  

  QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/98807
• Relton C, Blake MK, Bridge G et al. . Place-based household vouchers for locally supplied fruit and vegetables: the Fresh Street pilot cluster randomised controlled trial.

  
  

  DOI: 10.1186/s12889-024-21062-y

  
  

  QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/103443
• Greenwood K, Jones C, Yaziji N et al. (2024). The Early Youth Engagement (EYE-2) intervention in first-episode psychosis services: pragmatic cluster randomised controlled trial and cost-effectiveness evaluation..

  
  

  DOI: 10.1192/bjp.2024.154

  
  

  QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/101718
• Vollebregt PF, Goh YL, Chan CL et al. . Clinical effectiveness of subsensory sacral neuromodulation in adults with faecal incontinence: the SUBSoNIC crossover RCT and mechanistic study.

  
  

  DOI: 10.3310/jywt9670

  
  

  QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/102003
• de Abreu Nunes L, Hooper R, McGettigan P et al. . Statistical methods leveraging the hierarchical structure of adverse events for signal detection in clinical trials: a scoping review of the methodological literature.

  
  

  DOI: 10.1186/s12874-024-02369-1

  
  

  QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/100283
• Hooper R, Tovey D, Tricco AC et al. (2024). What advice can we offer to authors? Reflections from the statisticians’ bench.

  
  

  DOI: 10.1016/j.jclinepi.2024.111579

  
  

  QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/101425
• Hooper R, Quintin O, Kasza J (2024). Efficient designs for three-sequence stepped wedge trials with continuous recruitment.

  
  

  DOI: 10.1177/17407745241251780

  
  

  QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/95618
• Vollebregt P, Goh YL, Chan C et al. (2024). 483 EFFECT OF SUB-SENSORY SACRAL NEUROMODULATION ON FAECAL INCONTINENCE IN ADULTS: A RANDOMISED CROSSOVER TRIAL WITH COHORT FOLLOW-UP AND MECHANISTIC SUB-STUDY.

  
  

  DOI: 10.1016/s0016-5085(24)00745-5

  
  

  QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/97033
• Middelkoop K, Micklesfield LK, Walker N et al. (2024). Influence of vitamin D supplementation on bone mineral content, bone turnover markers, and fracture risk in South African schoolchildren: multicenter double-blind randomized placebo-controlled trial (ViDiKids).

  
  

  DOI: 10.1093/jbmr/zjae007

  
  

  QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/93972
• Sohanpal R, Pinnock H, Steed L et al. (2024). A tailored psychological intervention for anxiety and depression management in people with chronic obstructive pulmonary disease: TANDEM RCT and process evaluation.

  
  

  DOI: 10.3310/pawa7221

  
  

  QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/94083

Supervision

• Laeti de Abreu Nunes (Wellcome Trust PhD Programme in Science): Moving beyond frequency tables for the analysis and presentation of harm outcomes in randomised controlled trials

• Nadine Marlin (NIHR Doctoral Fellowship): Statistical methods for modelling complex associations in meta-analysis

• Olivier Quintin (NIHR Doctoral Fellowship): Developing guidance on the design and analysis of stepped wedge trials with small numbers of clusters
• Yuanjin Zhang (Trials Methodology Research Partnership DTP): Statistical methods for economic evaluations alongside stepped wedge cluster randomised controlled trials

PhD opportunity to start October 2025:

Optimal design for the next generation of stepped wedge trials