Dr Eva Galante

Profile

Dr Eva Galante is a Lecturer in in Pharmaceutical/Medicinal Chemistry and a Fellow of the Higher Education Academy.

Eva has a rich background in biomolecular and medicinal chemistry, combining research excellence with a strong dedication to teaching in higher education (HE). She began her academic journey in Italy at the National Council of Research (CNR), where her innovative research on natural products was awarded “Best National Project” by the Ministry of Education, University, and Research (MIUR) for technological innovation and industrial applications. Her expertise spans anti-tumour vaccine development and nuclear medicine, with notable contributions to projects aimed at diagnosing epilepsy and developing chemotherapeutics for neuroblastoma.

Eva has over 10 years of experience teaching in HE, where she prioritizes authentic learning and assessment practices to maximize students’ employability and readiness for the world of work. She integrates practical, real-world applications into her courses, fostering student engagement and deepening understanding through hands-on experiences. Passionate about advancing teaching and learning strategies, she actively explores innovative methods to create meaningful and inclusive learning environments. Her research interests continue to align with her teaching, focusing on medicinal chemistry and natural products, allowing her to bring cutting-edge insights to her students.

Undergraduate Teaching

Advanced Pharmaceutical Chemistry (CHE306)

Postgraduate Teaching

Fine-tuning Lead Compound (CHE702)

Fundamental of Medicinal Chemistry (CHE706)

Research

Publications

Selected Publications

E. Galante, T. Okamura, K. Sander, T. Kikuchi, M. Okada, M-R. Zhang, M. Robson, A. Badar, M.F. Lythgoe, M. Koepp, E. Årstad. Development of purine-derived 18F-labeled pro-drug tracers for imaging of MRP1 activity with PET. J. Med. Chem. 2014, 57, 1023-1032. https://doi.org/10.1021/jm401764a

E. Galante, B.W. Schoultz, M. Koepp, E. Årstad. Chelator-accelerated one-pot ‘click’ labeling of small molecule tracers with 2-[¹⁸F]fluoroethyl azide. Molecules 2013, 18, 5335-5347. https://doi.org/10.3390/molecules18055335

J. Valente, B. A. Pendry, E. Galante. Cranberry (Vaccinium macrocarpon) as a prophylaxis for urinary tract infections in women: A Systematic Review with Meta-Analysis. J. Herb. Med. 2022, 36, 100602. https://doi.org/10.1016/j.hermed.2022.100602

E. Galante, C. Geraci, S. Sciuto, V.L. Campo, I. Carvalho, R. Sesti-Costa, P.M.M. Guedes, J.S. Silva, L. Hill, S.A. Nepogodiev, R.A. Field. Glycoclusters presenting lactose on calix[4]arene cores display trypanocidal activity. Tetrahedron, 2011, 67, 5902 – 5912. https://doi.org/10.1016/j.tet.2011.06.065

R. Yan, K. Sander, E. Galante, V. Rajkumar, A. Badar, M. Robson, E. El-Emir, M.F. Lythgoe, R.B. Pedley, E. Årstad. A One-pot three-component radiochemical reaction for rapid assembly of 125I-labeled molecular probes. J. Am. Chem. Soc. 2013, 135, 703-709. https://doi.org/10.1021/ja307926g

M. Della Peruta, A. Badar, C. Rosales, S. Chokshi, A. Kia, D. Nathwani, E. Galante, R. Yan, E. Årstad, A.M. Davidoff, R. Williams, M.F. Lythgoe, A.C. Nathwani. Preferential targeting of disseminated liver tumors using a recombinant adeno-associated viral vector. Hum. Gene Ther. 2015, 26, 94-103. https://doi.org/10.1089/hum.2014.052

K. Sander, E. Galante, T. Gendron, E. Yiannaki, N. Patel, T.L. Kalber, A. Badar, M. Robson, S.P. Johnson, F. Bauer, S. Mairinger, J. Stanek, T. Wanek, C. Kuntner, T. Kottke, L. Weizel, D. Dickens, K. Erlandsson, B.F. Hutton, M.F. Lythgoe, H. Stark, O. Langer, M. Koepp, E. Årstad. Development of fluorine-18 labeled metabolically activated tracers for imaging of drug efflux transporters with PET. J. Med. Chem. 2015, 58, 15, 6058–6080. https://doi.org/10.1021/acs.jmedchem.5b00652

C. Geraci, G.M.L. Consoli, G. Granata, E. Galante, A. Palmigiano, M.S. Pappalardo, S. Di Puma, A. Spadaro. The first self-adjuvant multicomponent potential vaccine candidates by tethering of four or eight MUC1 antigenic immunodominant PDTRP units on a calixarene platform: synthesis and biological evaluation. Bioconjugate Chem. 2013, 24, 1710-1720. https://doi.org/10.1021/bc400242y

Performance

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