Professor Gareth Ackland

Profile

ORCID iD: 0000-0003-0565-5164

Gareth graduated from St John’s College, Oxford University Medical School having completed an intercalated PhD supported by a Wellcome Trust Prize Studentship. He completed clinical training in general medicine, anesthesiology and critical care mostly on the UCL-linked clinical rotation, having also spent 18 months as a consultant in anaesthesia at Stanford University Medical Center, California, USA. Having completed an Academy of Medical Sciences/Health Foundation clinician scientist intermediate research training fellowship award at University College London in 2014, Gareth was appointed Senior Lecturer in Perioperative Medicine at Queen Mary University of London in 2015 and Clinical Professor of Perioperative Medicine in 2020, primarily based at the William Harvey Research Institute.

Current clinical duties are based in perioperative medicine at the Royal London Hospital providing anaesthesia for patients undergoing major elective surgery and emergency procedures following major trauma. He is an active member of several national and international societies for anaesthesia and intensive care medicine. He teaches both undergraduate and postgraduate students. The focus of Gareth’s research centres on improving outcomes for patients following major surgery and critical illness through developing translational models, specifically focussing on autonomic regulation of tissue injury. In addition, he contributes to many large multi-centre studies including VISION-UK and METS. Gareth was awarded the British Oxygen Company Chair in anaesthesia in 2016, to support further translational laboratory studies focussed on the role of autonomic dysfunction fuelling perioperative organ injury.

Research

Group members

Ana Gutierrez del Arroyo, Jenifer Sanchez and Shamir Karmali

Summary

Neurobiology of autonomic control as applied to inflammation, perioperative organ injury and critical illness. 

Publications

• Hughes C, Ackland G, Shelley B (2024). Perioperative myocardial injury. nameOfConference

  
  

  DOI: 10.1016/j.bjae.2024.06.001

  
  

  QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/100697
• Theparambil SM, Kopach O, Braga A et al. (2024). Adenosine signalling to astrocytes coordinates brain metabolism and function. nameOfConference

  
  

  DOI: 10.1038/s41586-024-07611-w

  
  

  QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/97936
• Thomas M, Hayes K, White P et al. (2024). Early Intravenous Beta-Blockade with Esmolol in Adults with Severe Traumatic Brain Injury: A Phase 2a Intervention Design Study. nameOfConference

  
  

  DOI: 10.1007/s12028-024-02029-8

  
  

  QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/97937
• Mi Y, Burnham KL, Charles PD et al. (2024). High-throughput mass spectrometry maps the sepsis plasma proteome and differences in patient response. nameOfConference

  
  

  DOI: 10.1126/scitranslmed.adh0185

  
  

  QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/97369
• Vail EA, Ackland GL (2024). The BJA Editorial Fellowship 2024: a barometer for the state of academic anaesthesiology, perioperative, pain, and critical care medicine. nameOfConference

  
  

  DOI: 10.1016/j.bja.2024.03.041

  
  

  QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/97009
• Janssen H, Jhanji S, Oliver NS et al. (2024). Ward monitoring 4.0: real-time metabolic insights from continuous glucose monitoring into perioperative organ dysfunction. nameOfConference

  
  

  DOI: 10.1016/j.bja.2024.01.039

  
  

  QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/95278
• del Arroyo AG, Patel A, Abbott TEF et al. (2024). Preoperative N-terminal pro-B-type natriuretic peptide and myocardial injury after stopping or continuing renin–angiotensin system inhibitors in noncardiac surgery: a prespecified analysis of a phase 2 randomised controlled multicentre trial. nameOfConference

  
  

  DOI: 10.1016/j.bja.2024.01.010

  
  

  QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/96344
• Kellett DO, Aziz Q, Humphries JD et al. (2024). Transcriptional response of the heart to vagus nerve stimulation.. nameOfConference

  
  

  DOI: 10.6084/m9.figshare.24449590

  
  

  QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/98548
• Bollen Pinto B, Ackland GL (2024). Pathophysiological mechanisms underlying increased circulating cardiac troponin in noncardiac surgery: a narrative review. nameOfConference

  
  

  DOI: 10.1016/j.bja.2023.12.017

  
  

  QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/94218
• Prowle JR, Croal B, Abbott TEF et al. (2024). Cystatin C or creatinine for pre-operative assessment of kidney function and risk of post-operative acute kidney injury: a secondary analysis of the METS cohort study. nameOfConference

  
  

  DOI: 10.1093/ckj/sfae004

  
  

  QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/94510
• Polok K, Biccard BM, Chan MTV et al. (2024). Mortality and major postoperative complications within 1 year after vascular surgery: a prospective cohort study.. nameOfConference

  
  

  DOI: 10.20452/pamw.16645

  
  

  QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/96346
• Ackland GL, Martin T, Joseph M et al. (publicationYear). Transauricular nerve stimulation in acute ischaemic stroke requiring mechanical thrombectomy: Protocol for a phase 2A, proof-of-concept, sham-controlled randomised trial. nameOfConference

  
  

  DOI: 10.1371/journal.pone.0289719

  
  

  QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/93963
• Kellett DO, Aziz Q, Humphries JD et al. (2023). Transcriptional response of the heart to vagus nerve stimulation.. nameOfConference

  
  

  DOI: 10.1152/physiolgenomics.00095.2023

  
  

  QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/92696
• Lurati Buse G, Bollen Pinto B, Abelha F et al. (2023). ESAIC focused guideline for the use of cardiac biomarkers in perioperative risk evaluation. nameOfConference

  
  

  DOI: 10.1097/EJA.0000000000001865

  
  

  QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/89800
• Ackland G (2023). Discontinuation vs. continuation of renin–angiotensin system inhibition before non-cardiac surgery: the SPACE trial. nameOfConference

  
  

  DOI: 10.1093/eurheartj/ehad716

  
  

  QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/91917
• James A, Bruce D, Tetlow N et al. (2023). Heart rate recovery after orthostatic challenge and cardiopulmonary exercise testing in older individuals: prospective multicentre observational cohort study. nameOfConference

  
  

  DOI: 10.1016/j.bjao.2023.100238

  
  

  QMRO: qmroHref
• Roshanov PS, Chan MTV, Borges FK et al. (2024). One-year Outcomes after Discharge from Noncardiac Surgery and Association between Predischarge Complications and Death after Discharge: Analysis of the VISION Prospective Cohort Study. nameOfConference

  
  

  DOI: 10.1097/aln.0000000000004763

  
  

  QMRO: qmroHref
• Keast T, McErlane J, Kearns R et al. (2023). Study protocol for IMPRoVE: a multicentre prospective observational cohort study of the incidence, impact and mechanisms of perioperative right ventricular dysfunction in non-cardiac surgery. nameOfConference

  
  

  DOI: 10.1136/bmjopen-2023-074687

  
  

  QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/91915
• Korsak A, Kellett DO, Aziz Q et al. (2023). Immediate and sustained increases in the activity of vagal preganglionic neurons during exercise and after exercise training. nameOfConference

  
  

  DOI: 10.1093/cvr/cvad115

  
  

  QMRO: qmroHref
• Kopach O, Sylantyev S, Bard L et al. (2023). Human neutrophils communicate remotely via calcium-dependent glutamate-induced glutamate release. nameOfConference

  
  

  DOI: 10.1016/j.isci.2023.107236

  
  

  QMRO: qmroHref
• Thomas M, Hayes K, White P et al. (2024). Early Intravenous Beta-Blockade with Esmolol in Adults with Severe Traumatic Brain Injury (EBB-TBI): Protocol for a Phase 2a Intervention Design Study. nameOfConference

  
  

  DOI: 10.1007/s12028-023-01755-9

  
  

  QMRO: qmroHref
• Edwards MR, Forbes G, Walker N et al. (publicationYear). Fluid Optimisation in Emergency Laparotomy (FLO-ELA) Trial: study protocol for a multi-centre randomised trial of cardiac output-guided fluid therapy compared to usual care in patients undergoing major emergency gastrointestinal surgery. nameOfConference

  
  

  DOI: 10.1186/s13063-023-07275-3

  
  

  QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/90987
• Patel ABU, Bibawy PPWM, Althonayan JIM et al. (2023). Effect of transauricular nerve stimulation on perioperative pain: a single-blind, analyser-masked, randomised controlled trial. nameOfConference

  
  

  DOI: 10.1016/j.bja.2022.12.025

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/84581
• Lan-Pak-Kee V, Ackland GL, Egan TC et al. (2022). Arterial cannulation with ultrasound: clinical trial protocol for a randomised controlled trial comparing handheld ultrasound versus palpation technique for radial artery cannulation. nameOfConference

  
  

  DOI: 10.1016/j.bjao.2022.100111

  
  

  QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/88659
• Ackland G (2022). Statistical anaysis plan: VATS RCT.. nameOfConference

  
  

  DOI: doi

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/84703
• Walker SLM, Muthoo C, Sanchez J et al. (2022). Sex-specific differences in cardiac function, inflammation and injury during early polymicrobial sepsis. nameOfConference

  
  

  DOI: 10.1186/s40635-022-00454-7

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/79089
• Patel ABU, Bibawy PPWM, Majeed Z et al. (2022). Trans-auricular vagus nerve stimulation to reduce perioperative pain and morbidity: protocol for a single-blind analyser-masked randomised controlled trial. nameOfConference

  
  

  DOI: 10.1016/j.bjao.2022.100017

  
  

  QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/79103
• Ali A, Weber V, Thompson SJ et al. (2022). IL-1ra polymorphisms and risk of epidural-related maternal fever (EPIFEVER-2): study protocol for a multicentre, observational mechanistic cohort study. nameOfConference

  
  

  DOI: 10.1016/j.ijoa.2022.103540

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/77660
• Ackland G, ABBOTT T (2022). Hypotension as a marker or mediator of perioperative organ injury: a review. nameOfConference

  
  

  DOI: 10.1016/j.bja.2022.01.012

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/76744
• Abbott TEF, Ackland GL (2022). Reply to: Monitors are not a treatment.. nameOfConference

  
  

  DOI: 10.1097/EJA.0000000000001534

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/76375
• Jones TF, Iakovou D, Makariou N et al. (2022). Metformin and mortality after surgery: a systematic review and meta-analysis. nameOfConference

  
  

  DOI: 10.1016/j.bja.2022.01.001

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/76743
• Ackland GL, Walker SLM, Jones TF (2022). 2 The Inflammatory Response to Surgery. nameOfConference

  
  

  DOI: 10.1016/b978-0-323-56724-4.00002-2

  
  

  QMRO: qmroHref
• Ackland G, Van Duijvenboden S, ABBOTT T et al. (2021). Interleukin-1 receptor antagonist and risk of caesarean delivery after onset of labour: a Mendelian randomisation analysis.. nameOfConference

  
  

  DOI: 10.1016/j.bja.2021.09.039

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/74881
• Patel ABU, Weber V, Gourine AV et al. (2022). The potential for autonomic neuromodulation to reduce perioperative complications and pain: a systematic review and meta-analysis. nameOfConference

  
  

  DOI: 10.1016/j.bja.2021.08.037

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/75973
• May SM, Chiang E, Reyes A et al. (2021). Immunomodulation of innate immunity by brachial plexus blockade: a crossover study. nameOfConference

  
  

  DOI: 10.1016/j.bja.2021.06.010

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/74879
• May SM, Chiang E, Reyes A et al. (2021). Neuromodulation of innate immunity by remote ischaemic conditioning in humans: Experimental cross-over study. nameOfConference

  
  

  DOI: 10.1016/j.bbih.2021.100299

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/74872
• Heywood WE, Bliss E, Bahelil F et al. (2021). Proteomic signatures for perioperative oxygen delivery in skin after major elective surgery: mechanistic sub-study of a randomised controlled trial. nameOfConference

  
  

  DOI: 10.1016/j.bja.2021.06.003

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/73013
• Jones T, Gutierrez A, Arroyo D et al. (2021). O10: METFORMIN TREATMENT IMPROVES LYMPHOCYTE METABOLISM IN A MOUSE MODEL OF MAJOR SURGERY. nameOfConference

  
  

  DOI: 10.1093/bjs/znab117.010

  
  

  QMRO: qmroHref
• Schroth J, Weber V, Jones TF et al. (2021). Preoperative lymphopaenia, mortality, and morbidity after elective surgery: systematic review and meta-analysis. nameOfConference

  
  

  DOI: 10.1016/j.bja.2021.02.023

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/71492
• Pearse RM, Ackland GL, Asai T et al. (2021). Preprints in perioperative medicine: immediacy for the greater good. nameOfConference

  
  

  DOI: 10.1016/j.bja.2021.02.024

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/73035
• Farmer AD, Strzelczyk A, Finisguerra A et al. (publicationYear). International Consensus Based Review and Recommendations for Minimum Reporting Standards in Research on Transcutaneous Vagus Nerve Stimulation (Version 2020). nameOfConference

  
  

  DOI: 10.3389/fnhum.2020.568051

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/73081
• Abbott TEF, Howell S, Pearse RM et al. (2021). Mode of blood pressure monitoring and morbidity after noncardiac surgery: A prospective multicentre observational cohort study. nameOfConference

  
  

  DOI: 10.1097/EJA.0000000000001443

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/70172
• Weber V, Abbott TEF, Ackland GL (2021). Reducing the dose of neuromuscular blocking agents with adjuncts: a systematic review and meta-analysis. nameOfConference

  
  

  DOI: 10.1016/j.bja.2020.09.048

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/68841
• Booth LC, Yao ST, Korsak A et al. (2021). Selective optogenetic stimulation of efferent fibers in the vagus nerve of a large mammal. nameOfConference

  
  

  DOI: 10.1016/j.brs.2020.11.010

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/71245
• Shrimpton AJ, Walker SLM, Ackland GL (2020). Angiotensin converting enzyme inhibitors and angiotensin receptor blockers. nameOfConference

  
  

  DOI: 10.1016/j.bjae.2020.07.004

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/68403
• May S, Abbott TEF, Gutierrez Del Arroyo A et al. (2020). MicroRNA signatures of perioperative myocardial injury after elective noncardiac surgery: a prospective observational mechanistic cohort study. nameOfConference

  
  

  DOI: 10.1016/j.bja.2020.05.066

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/68429
• May SM, Abbott TEF, Del Arroyo AG et al. (2020). MicroRNA signatures of perioperative myocardial injury after elective noncardiac surgery: a prospective observational mechanistic cohort study. nameOfConference

  
  

  DOI: 10.1016/j.bja.2020.05.066

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/66357
• Riedel B, Li MHG, Lee CHA et al. (2020). A simplified (modified) Duke Activity Status Index (M-DASI) to characterise functional capacity: a secondary analysis of the Measurement of Exercise Tolerance before Surgery (METS) study. nameOfConference

  
  

  DOI: 10.1016/j.bja.2020.06.016

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/68649
• Machhada A, Hosford PS, Dyson A et al. (2020). Optogenetic Stimulation of Vagal Efferent Activity Preserves Left Ventricular Function in Experimental Heart Failure. nameOfConference

  
  

  DOI: 10.1016/j.jacbts.2020.06.002

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/68205
• Wan YI, Patel A, ABBOTT TEF et al. (2020). Prospective observational study of postoperative infection and outcomes after noncardiac surgery: analysis of prospective data from the VISION cohort. nameOfConference

  
  

  DOI: 10.1016/j.bja.2020.03.027

  
  

  QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/65271
• Hadjihambi A, Karagiannis A, Theparambil SM et al. (2020). The effect of general anaesthetics on brain lactate release. nameOfConference

  
  

  DOI: 10.1016/j.ejphar.2020.173188

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/66380
• Patel ABU, May SM, Reyes A et al. (2020). Elevated heart rate after noncardiac surgery: post hoc analysis of a prospective observational cohort study. nameOfConference

  
  

  DOI: 10.1016/j.bja.2019.11.015

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/71525
• Patel ABU, Stevens J, Ackland GL (2020). Experimental medicine in anaesthesia-related research: UK and US activity. nameOfConference

  
  

  DOI: 10.1016/j.bja.2019.11.018

  
  

  QMRO: qmroHref
• Walker SLM, Muthoo C, Sanchez J et al. (2020). Sex influences cardiac dysfunction in early polymicrobial sepsis, independent of leucocyte-derived tumour necrosis factor-α. nameOfConference

  
  

  DOI: 10.1016/j.bja.2019.11.011

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/68218
• Ackland GL, ABBOTT T, Jones TF et al. (2020). Early elevation in plasma high-sensitivity troponin T and morbidity after elective noncardiac surgery: prospective multicentre observational cohort study. nameOfConference

  
  

  DOI: 10.1016/j.bja.2020.02.003

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/63282
• Duceppe E, Patel A, Chan MTV et al. (2020). Preoperative n-terminal pro-b-type natriuretic peptide and cardiovascular events after noncardiac surgery: A cohort study. nameOfConference

  
  

  DOI: 10.7326/M19-2501

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/66668
• Ackland GL (2020). 40 What happens to the autonomic nervous system in critical illness?. nameOfConference

  
  

  DOI: 10.1016/b978-0-323-64068-8.00049-3

  
  

  QMRO: qmroHref
• Wijeysundera D, Beattie WS, Hillis G et al. (2020). Integration of the Duke Activity Status Index into Preoperative Risk Evaluation: A Multicentre Prospective Cohort Study. nameOfConference

  
  

  DOI: 10.1016/j.bja.2019.11.025

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/62126
• Ackland GL, Abbott TEF, Minto G et al. (publicationYear). Correction: Heart rate recovery and morbidity after noncardiac surgery: Planned secondary analysis of two prospective, multi-centre, blinded observational studies. nameOfConference

  
  

  DOI: 10.1371/journal.pone.0226379

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/71381
• Patel ABU, Ackland GL (publicationYear). Inotropes and Vasopressors for Shock. nameOfConference

  
  

  DOI: 10.2310/tywc.8001

  
  

  QMRO: qmroHref
• Patel ABU, May SM, Reyes A et al. (publicationYear). Elevated heart rate after non-cardiac surgery: post-hoc analysis of a prospective observational cohort study. nameOfConference

  
  

  DOI: 10.1101/19009530

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/71825
• Walker S, Del Arroyo AG, Sanchez J et al. (2019). P3509Leukocyte derived tumour necrosis factor modulates cardiac function in health and disease. nameOfConference

  
  

  DOI: 10.1093/eurheartj/ehz745.0373

  
  

  QMRO: qmroHref
• Zarbock A, Kellum JA, Gourine AV et al. (2020). Salvaging remote ischaemic preconditioning as a therapy for perioperative acute kidney injury. nameOfConference

  
  

  DOI: 10.1016/j.bja.2019.09.009

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/62205
• del Arroyo AG, Sanchez J, Reyes A et al. (2019). Bupivacaine reduces release of interleukin-1 receptor antagonist from circulating neutrophils obtained from women in active labour. nameOfConference

  
  

  DOI: 10.1016/j.bja.2019.04.012

  
  

  QMRO: qmroHref
• Reynolds J, May SM, Reyes A et al. (2019). Orthostatic autonomic dysfunction is associated with postoperative morbidity in patients undergoing noncardiac surgery. nameOfConference

  
  

  DOI: 10.1016/j.bja.2019.04.035

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/74874
• del Arroyo AG, Cyrus T, Bahelil F et al. (2019). Serial proteomic characterisation of skin during the perioperative period. nameOfConference

  
  

  DOI: 10.1016/j.bja.2019.04.038

  
  

  QMRO: qmroHref
• Manou-Stathopoulou V, Korbonits M, Ackland GL (2019). Redefining the perioperative stress response: a narrative review. nameOfConference

  
  

  DOI: 10.1016/j.bja.2019.08.011

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/62840
• Stephens TJ, Peden CJ, Haines R et al. (publicationYear). Hospital-level evaluation of the effect of a national quality improvement programme: time-series analysis of registry data. nameOfConference

  
  

  DOI: 10.1136/bmjqs-2019-009537

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/61464
• May SM, Reyes A, Martir G et al. (2019). Acquired loss of cardiac vagal activity is associated with myocardial injury in patients undergoing noncardiac surgery: prospective observational mechanistic cohort study. nameOfConference

  
  

  DOI: 10.1016/j.bja.2019.08.003

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/61920
• Peden CJ, Stephens T, Martin G et al. (publicationYear). A national quality improvement programme to improve survival after emergency abdominal surgery: the EPOCH stepped-wedge cluster RCT. nameOfConference

  
  

  DOI: 10.3310/hsdr07320

  
  

  QMRO: qmroHref
• del Arroyo AG, Hadjihambi A, Sanchez J et al. (2019). NMDA receptor modulation of glutamate release in activated neutrophils. nameOfConference

  
  

  DOI: 10.1016/j.ebiom.2019.08.004

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/60722
• Ackland GL, Abbott TEF, Minto G et al. (2019). Heart rate recovery and morbidity after noncardiac surgery: Planned secondary analysis of two prospective, multi-centre, blinded observational studies. nameOfConference

  
  

  DOI: 10.1371/journal.pone.0221277

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/61876
• The Vascular Events in Noncardiac Surgery Patients Cohort Evaluation (VISION) Study Investigators (2019). Association between complications and death within 30 days after noncardiac surgery.. nameOfConference

  
  

  DOI: 10.1503/cmaj.190221

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/60052
• Lau EYM, Carroll EC, Callender LA et al. (2019). Type 2 diabetes is associated with the accumulation of senescent T cells. nameOfConference

  
  

  DOI: 10.1111/cei.13344

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/58984
• Bartoszko J, Thorpe KE, Laupacis A et al. (2019). Association of preoperative anaemia with cardiopulmonary exercise capacity and postoperative outcomes in noncardiac surgery: a substudy of the Measurement of Exercise Tolerance before Surgery (METS) Study. nameOfConference

  
  

  DOI: 10.1016/j.bja.2019.04.058

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/58398
• Ackland GL, Pryor KO (2019). Electroencephalography-guided anaesthetic administration does not impact postoperative delirium among older adults undergoing major surgery: an independent discussion of the ENGAGES trial. nameOfConference

  
  

  DOI: 10.1016/j.bja.2019.03.016

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/59190
• ABBOTT TEF, PEARSE RM, beattie S et al. (2019). Chronotropic incompetence and myocardial injury after non-cardiac surgery: planned secondary analysis of a prospective observational international cohort study. nameOfConference

  
  

  DOI: 10.1016/j.bja.2019.03.022

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/56417
• PEARSE RM, Peden C, STEPHENS T et al. (2019). Effectiveness of a national quality improvement programme to improve survival after emergency abdominal surgery: A stepped-wedge cluster randomised trial. nameOfConference

  
  

  DOI: 10.1016/S0140-6736(18)32521-2

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/54603
• Manou-Stathopoulou V, Abbott TEF, May SM et al. (2019). Perioperative plasma cortisol levels and myocardial injury after non-cardiac surgery. nameOfConference

  
  

  DOI: 10.1016/j.bja.2018.10.034

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/71418
• May SM, Abbott TEF, Del Arroyo AG et al. (2019). Serum microRNAs and perioperative myocardial injury. nameOfConference

  
  

  DOI: 10.1016/j.bja.2018.10.033

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/71419
• Sessler DI, Bloomstone JA, Aronson S et al. (2019). Perioperative Quality Initiative consensus statement on intraoperative blood pressure, risk and outcomes for elective surgery. nameOfConference

  
  

  DOI: 10.1016/j.bja.2019.01.013

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/58425
• Ackland GL, Brudney CS, Cecconi M et al. (2019). Perioperative Quality Initiative consensus statement on the physiology of arterial blood pressure control in perioperative medicine. nameOfConference

  
  

  DOI: 10.1016/j.bja.2019.01.011

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/58876
• Pinto BB, Filipovic M, Ackland G (2019). Intra-operative heart rate and postoperative outcomes – rowing against the tide?. nameOfConference

  
  

  DOI: 10.1097/eja.0000000000000909

  
  

  QMRO: qmroHref
• McEvoy MD, Gupta R, Koepke EJ et al. (2019). Perioperative Quality Initiative consensus statement on postoperative blood pressure, risk and outcomes for elective surgery. nameOfConference

  
  

  DOI: 10.1016/j.bja.2019.01.019

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/58819
• Ackland GL (2019). Autonomic Dysfunction in Shock. nameOfConference

  
  

  DOI: 10.1007/978-3-319-69269-2_8

  
  

  QMRO: qmroHref
• Gourine AV, Ackland GL (2019). Cardiac Vagus and Exercise.. nameOfConference

  
  

  DOI: 10.1152/physiol.00041.2018

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/55136
• Abbott TEF, Pearse RM, Cuthbertson BH et al. (2019). Cardiac vagal dysfunction and myocardial injury after non-cardiac surgery: a planned secondary analysis of the measurement of Exercise Tolerance before surgery study. nameOfConference

  
  

  DOI: 10.1016/j.bja.2018.10.060

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/53303
• Walker S, Del Arroyo AG, Sanchez J et al. (2019). Leukocyte derived tumour necrosis factor modulates cardiac function in health and disease. nameOfConference

  
  

  DOI: doi

  
  

  QMRO: qmroHref
• ACKLAND GL (publicationYear). Perioperative Quality Initiative consensus statement on preoperative blood pressure, risk and outcomes for elective surgery. nameOfConference

  
  

  DOI: 10.1016/j.bja.2019.01.018

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/59001
• del Arroyo AG, Sanchez J, Patel S et al. (2018). Role of leucocyte caspase-1 activity in epidural-related maternal fever: a single-centre, observational, mechanistic cohort study. nameOfConference

  
  

  DOI: 10.1016/j.bja.2018.09.024

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/51743
• Ackland GL, Galley HF, Shelley B et al. (2018). Perioperative medicine and UK plc. nameOfConference

  
  

  DOI: 10.1016/j.bja.2018.09.023

  
  

  QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/51863
• Ackland GL, Abbott TEF, Cain D et al. (2019). Preoperative systemic inflammation and perioperative myocardial injury: prospective observational multicentre cohort study of patients undergoing non-cardiac surgery. nameOfConference

  
  

  DOI: 10.1016/j.bja.2018.09.002

  
  

  QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/49203
• TORRANCE H, LONGBOTTOM R, VIVIAN M et al. (2018). Post-operative immune suppression is mediated via reversible, Interleukin-10 dependent pathways in circulating monocytes following major abdominal surgery. nameOfConference

  
  

  DOI: 10.1371/journal.pone.0203795

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/45023
• Turner S-J, Jones T, Sanchez J et al. (2018). Clinical modulation of immunometabolism in sepsis. nameOfConference

  
  

  DOI: 10.1016/j.bja.2018.05.032

  
  

  QMRO: qmroHref
• Jones TF, Torrance HDT, Owen HC et al. (2018). MicroRNA profiles are associated with lymphocyte count after a major traumatic injury: a potential role for immunometabolism?. nameOfConference

  
  

  DOI: 10.1016/j.bja.2018.05.027

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/45685
• Ackland GL, Abbott TF, Pearse RM et al. (2018). Preoperative systemic inflammation and myocardial injury in non-cardiac surgery. nameOfConference

  
  

  DOI: 10.1016/j.bja.2018.05.021

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/71484
• Wijeysundera D, PEARSE R, shulman M et al. (2018). Assessment of functional capacity before major non-cardiac surgery: an international, prospective cohort study. nameOfConference

  
  

  DOI: 10.1016/S0140-6736(18)31131-0

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/42364
• WALKER S, ABBOTT TEF, Brown K et al. (2018). Perioperative management of angiotensin-converting enzyme inhibitors and/or angiotensin receptor blockers: a survey of perioperative medicine practitioners. nameOfConference

  
  

  DOI: 10.7717/peerj.5061

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/42127
• Lurati Buse G, Manns B, Lamy A et al. (2018). Troponin T monitoring to detect myocardial injury after noncardiac surgery: a cost–consequence analysis. nameOfConference

  
  

  DOI: 10.1503/cjs.010217

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/39863
• Ackland G, del Arroyo AG, Sanchez J et al. (2018). Caspase-1 and epidural-related maternal fever. nameOfConference

  
  

  DOI: 10.1016/j.bja.2017.11.050

  
  

  QMRO: qmroHref
• Walker S, Abbott T, Brown K et al. (2018). Contemporary perioperative management of ACE-inhibitors and angiotensin receptor blockers. nameOfConference

  
  

  DOI: 10.1016/j.bja.2017.11.057

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/71383
• May S, Karmali S, Reyes A et al. (2018). Serial holter recordings in non-cardiac surgery patients reveal postoperative autonomic impairment within 48 hours. nameOfConference

  
  

  DOI: 10.1016/j.bja.2017.11.042

  
  

  QMRO: qmroHref
• ackland GL, ABBOTT T, Pearse RM et al. (2018). Arterial pulse pressure and postoperative morbidity in high-risk surgical patients.. nameOfConference

  
  

  DOI: 10.1016/j.bja.2017.11.009

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/24953
• ABBOTT T, pearse RM, Archbold RA et al. (2018). A Prospective International Multicentre Cohort Study of Intraoperative Heart Rate and Systolic Blood Pressure and Myocardial Injury After Noncardiac Surgery: Results of the VISION Study. nameOfConference

  
  

  DOI: 10.1213/ANE.0000000000002560

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/36643
• ACKLAND GL, Minto G, Clark M et al. (publicationYear). Autonomic regulation of systemic inflammation in humans: a multi-center, blinded observational cohort study.. nameOfConference

  
  

  DOI: 10.1016/j.bbi.2017.08.010

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/25329
• Karmali SN, Sciusco A, May SM et al. (2017). Heart rate variability in critical care medicine: a systematic review. nameOfConference

  
  

  DOI: 10.1186/s40635-017-0146-1

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/25320
• ABBOTT T, pearse R, ahmad T et al. (2017). Association between preoperative pulse pressure and perioperative myocardial injury: an international observational cohort study of patients undergoing non-cardiac surgery. nameOfConference

  
  

  DOI: 10.1093/bja/aex165

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/25477
• ABBOTT T, Lee A, Pearse R et al. (2017). Elevated preoperative heart rate is associated with cardiopulmonary and autonomic impairment in high-risk surgical patients.. nameOfConference

  
  

  DOI: 10.1093/bja/aex164

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/25476
• Machhada A, Trapp S, Marina N et al. (publicationYear). Vagal determinants of exercise capacity. nameOfConference

  
  

  DOI: 10.1038/ncomms15097

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/24525
• Biccard BM, Scott DJA, Chan MTV et al. (2017). Myocardial Injury After Noncardiac Surgery (MINS) in Vascular Surgical Patients: A Prospective Observational Cohort Study.. nameOfConference

  
  

  DOI: 10.1097/SLA.0000000000002290

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/23524
• Writing Committee for the VISION Study Investigators, Devereaux PJ, Biccard BM et al. (2017). Association of Postoperative High-Sensitivity Troponin Levels With Myocardial Injury and 30-Day Mortality Among Patients Undergoing Noncardiac Surgery.. nameOfConference

  
  

  DOI: 10.1001/jama.2017.4360

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/58626
• O'Connor ME, Hewson RW, Kirwan CJ et al. (publicationYear). Acute kidney injury and mortality 1 year after major non-cardiac surgery. nameOfConference

  
  

  DOI: 10.1002/bjs.10498

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/19798
• Patel A, Prowle JR, Ackland GL et al. (2017). Postoperative goal-directed therapy and development of acute kidney injury following major elective noncardiac surgery: post-hoc analysis of POM-O randomized controlled trial. nameOfConference

  
  

  DOI: 10.1093/ckj/sfw118

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/24486
• Basalay M, Mastitskaya S, Mrochek A et al. (2017). Reply: Glucagon-like peptide-1 mediates cardioprotection by remote ischaemic conditioning.. nameOfConference

  
  

  DOI: 10.1093/cvr/cvw238

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/61678
• Turovsky E, Theparambil SM, Kasymov V et al. (2016). Mechanisms of CO2/H+ Sensitivity of Astrocytes. nameOfConference

  
  

  DOI: 10.1523/jneurosci.1281-16.2016

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/23060
• Basalay MV, Mastitskaya S, Mrochek A et al. (2016). Glucagon-like peptide-1 (GLP-1) mediates cardioprotection by remote ischaemic conditioning. nameOfConference

  
  

  DOI: 10.1093/cvr/cvw216

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/16286
• Toner A, Jenkins N, Ackland GL (2016). Baroreflex impairment and morbidity after major surgery. nameOfConference

  
  

  DOI: 10.1093/bja/aew257

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/15182
• Ackland GL, Whittle J, Toner A et al. (2016). Molecular Mechanisms Linking Autonomic Dysfunction and Impaired Cardiac Contractility in Critical Illness.. nameOfConference

  
  

  DOI: 10.1097/CCM.0000000000001606

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/12159
• Abbott TEF, Ackland GL, Archbold RA et al. (2016). Preoperative heart rate and myocardial injury after non-cardiac surgery: results of a predefined secondary analysis of the VISION study. nameOfConference

  
  

  DOI: 10.1093/bja/aew182

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/13922
• Marina N, Kasymov V, Ackland GL et al. (2016). Astrocytes and Brain Hypoxia. nameOfConference

  
  

  DOI: 10.1007/978-1-4899-7678-9_14

  
  

  QMRO: qmroHref
• Ackland GL, Stephens RCM (2016). Big Data: A Cheerleader for Translational Perioperative Medicine.. nameOfConference

  
  

  DOI: 10.1213/ANE.0000000000001286

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/16007
• Sultan P, David AL, Fernando R et al. (2016). Inflammation and Epidural-Related Maternal Fever. nameOfConference

  
  

  DOI: 10.1213/ANE.0000000000001195

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/12269
• Wijeysundera DN, Pearse RM, Shulman MA et al. (2016). Measurement of Exercise Tolerance before Surgery (METS) study: a protocol for an international multicentre prospective cohort study of cardiopulmonary exercise testing prior to major non-cardiac surgery.. nameOfConference

  
  

  DOI: 10.1136/bmjopen-2015-010359

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/12155
• Nelson A, Otto J, Whittle J et al. (2016). Subclinical cardiopulmonary dysfunction in stage 3 chronic kidney disease. nameOfConference

  
  

  DOI: 10.1136/openhrt-2015-000370

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/12835
• Abbott T, Ackland GL, Wragg A et al. (2015). Association between intraoperative heart rate and postoperative myocardial injury in patients following non-cardiac surgery.. nameOfConference

  
  

  DOI: 10.1186/2197-425X-3-S1-A751

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/71828
• Abbott T, Ackland G, Wragg A et al. (2015). Association of preoperative heart rate with postoperative myocardial injury. nameOfConference

  
  

  DOI: doi

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/15463
• Patel ABU, Reyes A, Ackland GL (publicationYear). Non-inferiority of retrospective data collection for assessing perioperative morbidity. nameOfConference

  
  

  DOI: 10.7717/peerj.1466

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/13270
• Whittle J, Nelson A, Otto JM et al. (2015). Sympathetic autonomic dysfunction and impaired cardiovascular performance in higher risk surgical patients: implications for perioperative sympatholysis. nameOfConference

  
  

  DOI: 10.1136/openhrt-2015-000268

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/12977
• Karmali S, Jenkins N, Sciusco A et al. (2015). Randomized controlled trial of vagal modulation by sham feeding in elective non-gastrointestinal (orthopaedic) surgery. nameOfConference

  
  

  DOI: 10.1093/bja/aev283

  
  

  QMRO: qmroHref
• Machhada A, Gourine AV, Ackland GL (2015). Vagal Modulation of Atrial Fibrillation. nameOfConference

  
  

  DOI: 10.1016/j.jacc.2015.04.083

  
  

  QMRO: qmroHref
• Angelova PR, Kasymov V, Christie I et al. (2015). Functional Oxygen Sensitivity of Astrocytes. nameOfConference

  
  

  DOI: 10.1523/jneurosci.0045-15.2015

  
  

  QMRO: qmroHref
• Edwards MR, Sultan P, del Arroyo AG et al. (2015). Metabolic dysfunction in lymphocytes promotes postoperative morbidity.. nameOfConference

  
  

  DOI: 10.1042/cs20150024

  
  

  QMRO: qmroHref
• Machhada A, Ang R, Ackland GL et al. (2015). Control of ventricular excitability by neurons of the dorsal motor nucleus of the vagus nerve. nameOfConference

  
  

  DOI: 10.1016/j.hrthm.2015.06.005

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/13063
• Abbott T, Rodseth R, Le Manach Y et al. (2015). Association between preoperative resting heart rate and postoperative myocardial injury in patients undergoing non-cardiac surgery. nameOfConference

  
  

  DOI: 10.1186/2197-425X-3-S1-A751

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/14811
• Milne A, Mon WY, Down J et al. (2015). Contemporary Perioperative Management of Adult Familial Dysautonomia (Riley-Day Syndrome). nameOfConference

  
  

  DOI: 10.1213/xaa.0000000000000141

  
  

  QMRO: qmroHref
• Ackland GL, Cecconi M, Pearse RM (2015). Individualised targeted haemodynamic therapy in high-risk surgical patients - authors' reply.. nameOfConference

  
  

  DOI: 10.1016/s2213-2600(15)00100-9

  
  

  QMRO: qmroHref
• Ackland GL, Prowle JR (2015). Presepsin: solving a soluble (CD14) problem in sepsis?. nameOfConference

  
  

  DOI: 10.1007/s00134-014-3642-8

  
  

  QMRO: qmroHref
• Cain DJ, del Arroyo AG, Ackland GL (2015). Man is the new mouse: Elective surgery as a key translational model for multi-organ dysfunction and sepsis. nameOfConference

  
  

  DOI: 10.1177/1751143714564826

  
  

  QMRO: qmroHref
• Karmali S, Reyes A, Barnett S et al. (2015). Frailty and postoperative morbidity following elective orthopaedic surgery. nameOfConference

  
  

  DOI: doi

  
  

  QMRO: qmroHref
• Ackland GL (2015). Heart Failure and Perioperative Care. nameOfConference

  
  

  DOI: 10.1097/asa.0000000000000027

  
  

  QMRO: qmroHref
• Karmali S, Jenkins N, Davies K et al. (2015). Vagal modulation by sham feeding and post-operative gastrointestinal dysfunction following elective orthopaedic surgery. nameOfConference

  
  

  DOI: doi

  
  

  QMRO: qmroHref
• Ackland GL, Iqbal S, Paredes LG et al. (2015). Individualised oxygen delivery targeted haemodynamic therapy in high-risk surgical patients: a multicentre, randomised, double-blind, controlled, mechanistic trial. nameOfConference

  
  

  DOI: 10.1016/s2213-2600(14)70205-x

  
  

  QMRO: qmroHref
• Barsukevich V, Basalay M, Sanchez J et al. (2015). Distinct cardioprotective mechanisms of immediate, early and delayed ischaemic postconditioning. nameOfConference

  
  

  DOI: 10.1007/s00395-014-0452-7

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/12974
• Ackland GL, Laing CM (2014). Chronic kidney disease: a gateway for perioperative medicine. nameOfConference

  
  

  DOI: 10.1093/bja/aeu222

  
  

  QMRO: qmroHref
• Sultan P, Edwards MR, del Arroyo AG et al. (2014). Cardiopulmonary Exercise Capacity and Preoperative Markers of Inflammation. nameOfConference

  
  

  DOI: 10.1155/2014/727451

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/12973
• Pearse RM, Harrison DA, MacDonald N et al. (2014). Effect of a Perioperative, Cardiac Output–Guided Hemodynamic Therapy Algorithm on Outcomes Following Major Gastrointestinal Surgery: A Randomized Clinical Trial and Systematic Review. nameOfConference

  
  

  DOI: 10.1001/jama.2014.5305

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/11483
• Fragkou P, Torrance H, Ackland G et al. (2014). Major gastrointestinal surgery is associated with a specific gene expression profile that is quantitatively associated with infectious complications. nameOfConference

  
  

  DOI: 10.1097/00003643-201406001-00037

  
  

  QMRO: qmroHref
• Fragkou P, Prowle J, Ackland G et al. (2014). Perioperative blood transfusion is associated with a characteristic immune response, excess infectious complications and death in patients undergoing scheduled major gastrointestinal surgery. nameOfConference

  
  

  DOI: 10.1097/00003643-201406001-00249

  
  

  QMRO: qmroHref
• Botto F, Alonso-Coello P, Chan MTV et al. (2014). Myocardial Injury after Noncardiac Surgery. nameOfConference

  
  

  DOI: 10.1097/aln.0000000000000113

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/9817
• Cain DJ, del Arroyo AG, Ackland GL (2014). Uncontrolled sepsis: a systematic review of translational immunology studies in intensive care medicine. nameOfConference

  
  

  DOI: 10.1186/2197-425x-2-6

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/13410
• Henderson WR, Barnbrook J, Dominelli PB et al. (2014). Administration of intrapulmonary sodium polyacrylate to induce lung injury for the development of a porcine model of early acute respiratory distress syndrome. nameOfConference

  
  

  DOI: 10.1186/2197-425x-2-5

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/12975
• Machhada A, Ang R, Ninkina N et al. (2014). A CNS cell group that controls electrical stability of the heart. nameOfConference

  
  

  DOI: doi

  
  

  QMRO: qmroHref
• Fragkou PC, Torrance HD, Pearse RM et al. (2014). Perioperative blood transfusion is associated with a gene transcription profile characteristic of immunosuppression: a prospective cohort study. nameOfConference

  
  

  DOI: 10.1186/s13054-014-0541-x

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/12111
• Abbott T, Ackland GL (2014). The relationships between anesthesia, hemodynamics and outcome. nameOfConference

  
  

  DOI: 10.1017/cbo9781107257115.027

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/71877
• Machhada A, Gourine AV, Lythgoe MF et al. (2014). Vagal mechanisms controlling exercise capacity. nameOfConference

  
  

  DOI: doi

  
  

  QMRO: qmroHref
• Ackland GL, Kazymov V, Marina N et al. (2013). Peripheral Neural Detection of Danger–Associated and Pathogen–Associated Molecular Patterns. nameOfConference

  
  

  DOI: 10.1097/ccm.0b013e31827c0b05

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/12972
• Ackland G, Mythen M (2006). Physiology of the Gastrointestinal Tract Including Splanchnic Blood Flow and Tonometry. nameOfConference

  
  

  DOI: 10.3109/9781420014068-2

  
  

  QMRO: qmroHref
• Toner A, Whittle J, Ackland GL (2013). Autonomic Dysfunction Is the Motor of Chronic Critical Illness. nameOfConference

  
  

  DOI: 10.1007/978-3-642-35109-9_16

  
  

  QMRO: qmroHref
• Pearse, Ackland (2012). Perioperative fluid therapy.. nameOfConference

  
  

  DOI: 10.1024/1661-8157/a001028

  
  

  QMRO: qmroHref
• Mastitskaya S, Marina N, Gourine A et al. (2012). Cardioprotection evoked by remote ischaemic preconditioning is critically dependent on the activity of vagal pre-ganglionic neurones. nameOfConference

  
  

  DOI: 10.1093/cvr/cvs212

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/12971
• Basalay M, Barsukevich V, Mastitskaya S et al. (2012). Remote ischaemic pre‐ and delayed postconditioning – similar degree of cardioprotection but distinct mechanisms. nameOfConference

  
  

  DOI: 10.1113/expphysiol.2012.064923

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/15422
• Cain D, Ackland G (2012). Knowing the risk? NCEPOD 2011: a wake-up call for perioperative practice. nameOfConference

  
  

  DOI: 10.12968/hmed.2012.73.5.262

  
  

  QMRO: qmroHref
• Pearse RM, Ackland GL (2012). Perioperative fluid therapy. nameOfConference

  
  

  DOI: 10.1136/bmj.e2865

  
  

  QMRO: qmroHref
• Dyson A, Cone S, Singer M et al. (2012). Microvascular and macrovascular flow are uncoupled in early polymicrobial sepsis. nameOfConference

  
  

  DOI: 10.1093/bja/aes093

  
  

  QMRO: qmroHref
• Ackland GL (2012). In Response. nameOfConference

  
  

  DOI: 10.1213/ane.0b013e318245dd26

  
  

  QMRO: qmroHref
• Sultan P, Hamilton MA, Ackland GL (2012). Preoperative muscle weakness as defined by handgrip strength and postoperative outcomes: a systematic review. nameOfConference

  
  

  DOI: 10.1186/1471-2253-12-1

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/12993
• Ackland GL, Moran N, Cone S et al. (2011). Chronic Kidney Disease and Postoperative Morbidity After Elective Orthopedic Surgery. nameOfConference

  
  

  DOI: 10.1097/01.sa.0000407028.88835.36

  
  

  QMRO: qmroHref
• Holm L, Ackland GL, Edwards MR et al. (2012). Chemical labelling of active serum thioester proteins for quantification. nameOfConference

  
  

  DOI: 10.1016/j.imbio.2011.07.021

  
  

  QMRO: qmroHref
• Ackland GL (2011). Reply from the authors. nameOfConference

  
  

  DOI: 10.1093/bja/aer070

  
  

  QMRO: qmroHref
• Edwards M, Whittle J, Ackland GL (2011). Biomarkers to guide perioperative management. nameOfConference

  
  

  DOI: 10.1136/pgmj.2010.107177

  
  

  QMRO: qmroHref
• Cross J, Edwards M, Harrison S et al. (2011). Morbidity following complex EVAR. nameOfConference

  
  

  DOI: 10.1016/j.ijsu.2011.07.400

  
  

  QMRO: qmroHref
• Ackland GL, Dyson A, Singer M (2010). Arterial Hyperoxia and In-Hospital Mortality After Resuscitation From Cardiac Arrest. nameOfConference

  
  

  DOI: 10.1001/jama.2010.1396

  
  

  QMRO: qmroHref
• Ackland GL, Harris S, Ziabari Y et al. (2010). Revised cardiac risk index and postoperative morbidity after elective orthopaedic surgery: a prospective cohort study. nameOfConference

  
  

  DOI: 10.1093/bja/aeq245

  
  

  QMRO: qmroHref
• Barnes SJ, Ackland GL (2010). Beta-adrenoreceptor modulation of metabolic, endocrine and immunologic function during critical illness.. nameOfConference

  
  

  DOI: 10.2174/187153010791936883

  
  

  QMRO: qmroHref
• Ackland GL, Moran N, Cone S et al. (2011). Chronic Kidney Disease and Postoperative Morbidity After Elective Orthopedic Surgery. nameOfConference

  
  

  DOI: 10.1213/ane.0b013e3181ee8456

  
  

  QMRO: qmroHref
• Ackland GL, Edwards M (2010). Defining higher-risk surgery. nameOfConference

  
  

  DOI: 10.1097/mcc.0b013e328339fad5

  
  

  QMRO: qmroHref
• Ackland GL, Yao ST, Rudiger A et al. (2010). Cardioprotection, attenuated systemic inflammation, and survival benefit of β1-adrenoceptor blockade in severe sepsis in rats*. nameOfConference

  
  

  DOI: 10.1097/ccm.0b013e3181c03dfa

  
  

  QMRO: qmroHref
• Ackland GL, Del Arroyo AG, Yao ST et al. (2010). Low-molecular-weight polyethylene glycol improves survival in experimental sepsis*. nameOfConference

  
  

  DOI: 10.1097/ccm.0b013e3181c8fcd0

  
  

  QMRO: qmroHref
• Barnes SJ, Singer M, Ackland GL (2010). DOBUTAMINE STRESS ECHOCARDIOGRAPHY UNMASKS MYOCARDIAL DYSFUNCTION IN EARLY RODENT POLYMICROBIAL SEPSIS. nameOfConference

  
  

  DOI: doi

  
  

  QMRO: qmroHref
• del Arroyo AG, Singer M, Ackland GL (2010). NEURO-IMMUNOMODULATION OF HUMAN CD14+CD16+NEUTROPHILS IN SEPSIS. nameOfConference

  
  

  DOI: doi

  
  

  QMRO: qmroHref
• Paschalis A, Churchill L, Marina N et al. (2009). β1-Adrenoceptor distribution in the rat brain: An immunohistochemical study. nameOfConference

  
  

  DOI: 10.1016/j.neulet.2009.04.023

  
  

  QMRO: qmroHref
• Ackland G, Agrawal R, Hou C et al. (2009). Strain-specific and pathogen-specific physiologic and genomic differences in murine inflammatory cardiac dysfunction. nameOfConference

  
  

  DOI: 10.1186/cc7534

  
  

  QMRO: qmroHref
• Ackland GL, Patterson AJ (2009). The Pivotal Role of Beta-adrenoreceptors in Critical Illness Pathophysiology. nameOfConference

  
  

  DOI: 10.1007/978-0-387-92278-2_15

  
  

  QMRO: qmroHref
• Ackland G (2001). Physical incompatibility between atracurium and intravenous diclofenac. nameOfConference

  
  

  DOI: 10.1046/j.1365-2044.2001.01918-33.x

  
  

  QMRO: qmroHref
• Ackland GL, O’Beirne J, Platts AR et al. (2008). False-Positive Presentation of Battle’s Sign During Hepatic Encephalopathy. nameOfConference

  
  

  DOI: 10.1007/s12028-008-9116-5

  
  

  QMRO: qmroHref
• Ackland GL, Harrington J, Downie P et al. (2008). Dehydration Induced by Bowel Preparation in Older Adults Does Not Result in Cognitive Dysfunction. nameOfConference

  
  

  DOI: 10.1213/ane.0b013e3181615247

  
  

  QMRO: qmroHref
• Ackland GL, Mythen MG (2007). Novel biomarkers in critical care: utility or futility?. nameOfConference

  
  

  DOI: 10.1186/cc6127

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/14988
• Ackland GL, Kasymov V, Gourine AV (2007). Physiological and pathophysiological roles of extracellular ATP in chemosensory control of breathing. nameOfConference

  
  

  DOI: 10.1042/bst0351264

  
  

  QMRO: qmroHref
• Ackland GL, Scollay JM, Parks RW et al. (2007). Pre‐operative high sensitivity C‐reactive protein and postoperative outcome in patients undergoing elective orthopaedic surgery. nameOfConference

  
  

  DOI: 10.1111/j.1365-2044.2007.05176.x

  
  

  QMRO: qmroHref
• Ackland GL, Smith M, McGlennan AP (2007). Acute, Severe Hypoglycemia Occurring During General Anesthesia in a Nondiabetic Adult. nameOfConference

  
  

  DOI: 10.1213/01.ane.0000268143.05226.a0

  
  

  QMRO: qmroHref
• Ackland G (2006). Perioperative beta-blockade: beyond myocardial ischaemia. nameOfConference

  
  

  DOI: 10.12968/hmed.2006.67.5.21082

  
  

  QMRO: qmroHref
• Hamilton MA, Mythen MG, Ackland GL (2006). Less Is Not More: A Lack of Evidence for Intraoperative Fluid Restriction Improving Outcome After Major Elective Gastrointestinal Surgery. nameOfConference

  
  

  DOI: 10.1213/01.ane.0000190877.56380.fe

  
  

  QMRO: qmroHref
• Spyer KM, Ackland GL, Gourine AV (2006). NEUROPHYSIOLOGY. nameOfConference

  
  

  DOI: 10.1016/B0-12-370879-6/00500-7

  
  

  QMRO: qmroHref
• Spyer KM, Ackland GL, Gourine AV (2006). NEUROPHYSIOLOGY | Overview. nameOfConference

  
  

  DOI: 10.1016/b0-12-370879-6/00500-7

  
  

  QMRO: qmroHref
• Ackland GL, Fox R (2005). Low-dose Propofol Infusion for Controlling Acute Hyperspasticity after Withdrawal of Intrathecal Baclofen Therapy. nameOfConference

  
  

  DOI: 10.1097/00000542-200509000-00033

  
  

  QMRO: qmroHref
• Ackland GL, Mythen MG (2005). Negative Pressure Pulmonary Edema as an Unsuspected Imitator of Acute Lung Injury/ARDS. nameOfConference

  
  

  DOI: 10.1378/chest.127.5.1867-a

  
  

  QMRO: qmroHref
• Ackland GL, Singh-Ranger D, Fox S et al. (2004). Assessment of preoperative fluid depletion using bioimpedance analysis. nameOfConference

  
  

  DOI: 10.1093/bja/aeh015

  
  

  QMRO: qmroHref
• Ackland GL, Gourine AV, Spyer KM (2003). Endotoxin impairs the hypoxic ventilatory response in anaesthetized adult rats. nameOfConference

  
  

  DOI: doi

  
  

  QMRO: qmroHref
• Ackland G (2002). Effect of low‐dose volatile anaesthetics on ventilation during acute hypoxia. nameOfConference

  
  

  DOI: 10.1046/j.1365-2044.2002.02913_20.x

  
  

  QMRO: qmroHref
• Ackland G, Grocott MP, Mythen MG (2000). Understanding gastrointestinal perfusion in critical care: so near, and yet so far. nameOfConference

  
  

  DOI: 10.1186/cc709

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/74880
• Ackland GL, Noble R, Hanson MA (1997). Red nucleus inhibits breathing during hypoxia in neonates1Paper presented at the conference of Neural Control of Breathing: Molecular to Organismal Perspectives, Madison, WI, 21–25 July 1996.1. nameOfConference

  
  

  DOI: 10.1016/s0034-5687(97)00090-x

  
  

  QMRO: qmroHref
• Moore PJ, Ackland GL, Hanson MA (1996). Unilateral cooling in the region of locus coeruleus blocks the fall in respiratory output during hypoxia in anaesthetized neonatal sheep. nameOfConference

  
  

  DOI: 10.1113/expphysiol.1996.sp003998

  
  

  QMRO: qmroHref
• Waites BA, Ackland GL, Noble R et al. (1996). Red nucleus lesions abolish the biphasic respiratory response to isocapnic hypoxia in decerebrate young rabbits.. nameOfConference

  
  

  DOI: 10.1113/jphysiol.1996.sp021586

  
  

  QMRO: qmroHref
• ACKLAND GL, WAITES BA, NOBLE R et al. (1995). BILATERAL LESIONS IN THE RED NUCLEUS ABOLISH THE BIPHASIC RESPIRATORY RESPONSE TO HYPOXIA IN DECEREBRATE NEWBORN RABBITS. nameOfConference

  
  

  DOI: doi

  
  

  QMRO: qmroHref
• WAITES BA, ACKLAND GL, NOBLE R et al. (1995). MICROINJECTION OF L-GLUTAMATE IN THE RED NUCLEUS PRODUCES INHIBITION OF RESPIRATORY OUTPUT IN DECEREBRATE NEONATAL RABBITS. nameOfConference

  
  

  DOI: doi

  
  

  QMRO: qmroHref
• Ackland GL, Moore PJ, Hanson MA (1994). Is the Ventilatory Decline Seen in Newborns during Hypoxaemia Centrally Mediated?. nameOfConference

  
  

  DOI: 10.1007/978-1-4615-2572-1_63

  
  

  QMRO: qmroHref
• Ackland GL, Moore PJ, Hanson MA (1993). Hypoxia inhibits the effect on breathing of transient chemoreceptor stimulation in anaesthetized newborn rabbits. nameOfConference

  
  

  DOI: doi

  
  

  QMRO: qmroHref
• THOMAS JM, MACKRODT WC, ACKLAND G (1992). CLASSICAL AND QUANTUM SIMULATION OF THE SURFACE-PROPERTIES OF ALPHA-AL2O3 - DISCUSSION. nameOfConference

  
  

  DOI: doi

  
  

  QMRO: qmroHref

Collaborators

Internal

• Prof. Rupert Pearse
• Dr. Michael O’Dwyer
• Dr. John Prowle
• Dr. Sian Henson
• Prof. Andy Tinker
  

External

• Prof. Alexander Gourine (UCL)
• Prof. Andrey Abramov (UCL)
• Prof Andrew Tobin (Univ. Cambridge)
• Prof. Pierre Lambiase (UCL)