Professor Charles Hinds

Profile

Charles Hinds qualified at St. Bartholomew’s Hospital in 1972 and was appointed as Consultant and Senior Lecturer in Anaesthesia and Intensive Care at the same hospital in 1980. Subsequently, he was Director of the Intensive Unit at Barts, and later for the combined Barts and The London NHS Trust, for more than 15 years. He is a past President of the Intensive Care Society and was Chairman of Examiners for the UK Diploma of Intensive Care. He was UK Representative for the European Society of Intensive Care Medicine and a member of the Education and Training Subcommittee of the ESICM. He was for many years a member of the Research Committee of the Intensive Care Society. In January 2007 Professor Hinds was awarded a College Medal by the Royal College of Anaesthetists as a mark of distinction for his work in helping the College to achieve its aims and for his support for the speciality. He was subsequently invited to deliver the Samuel Thompson Rowling oration at the College. In 2013 Prof. Hinds was awarded Honorary Lifetime Memberships of the ESICM and UK Intensive Care Society. Together with Prof. Watson, Professor Hinds has published three editions of their popular textbook: Intensive Care: A concise textbook. Professor Hinds was recently awarded a Gold Medal by the Faculty of Intensive Care Medicine.

Memberships and awards

• Honorary Lifetime Member of the European Society of Intensive Care Medicine and the UK Intensive Care Society
• Royal College of Anaesthetists College Medal
• Gold Medal of the Faculty of Intensive Care Medicine

Research

Critical Care and Perioperative Medicine Research Group

Group members

• Professor Gareth Ackland
• Professor Mark Griffiths
• Professor Rupert Pearse
• Dr John Prowle
• Dr Zudin Pulthucheary
• Dr Parjam Zolfaghari
• Dr Alastair Proudfoot
  

Summary 

Publications

• Mi Y, Burnham KL, Charles PD et al. (2024). High-throughput mass spectrometry maps the sepsis plasma proteome and differences in patient response.

  
  

  DOI: 10.1126/scitranslmed.adh0185

  
  

  QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/97369
• Antcliffe DB, Mi Y, Santhakumaran S et al. (2024). Patient stratification using plasma cytokines and their regulators in sepsis: relationship to outcomes, treatment effect and leucocyte transcriptomic subphenotypes.

  
  

  DOI: 10.1136/thorax-2023-220538

  
  

  QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/100694
• Torrance HD, Zhang P, Longbottom ER et al. (2024). A Transcriptomic Approach to Understand Patient Susceptibility to Pneumonia After Abdominal Surgery.

  
  

  DOI: 10.1097/sla.0000000000006050

  
  

  QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/89968
• Kwok AJ, Allcock A, Ferreira RC et al. (2023). Neutrophils and emergency granulopoiesis drive immune suppression and an extreme response endotype during sepsis.

  
  

  DOI: 10.1038/s41590-023-01490-5

  
  

  QMRO:
• Cano-Gamez E, Burnham KL, Goh C et al. (2022). An immune dysfunction score for stratification of patients with acute infection based on whole-blood gene expression.

  
  

  DOI: 10.1126/scitranslmed.abq4433

  
  

  QMRO:
• Baillie JK, Begg C, Clohisey Hendry S et al. (2022). Whole-genome sequencing reveals host factors underlying critical COVID-19.

  
  

  DOI: 10.1038/s41586-022-04576-6

  
  

  QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/80960
• Consortium CM-OBA, Ahern DJ, Ai Z et al. (2022). A blood atlas of COVID-19 defines hallmarks of disease severity and specificity.

  
  

  DOI: 10.1016/j.cell.2022.01.012

  
  

  QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/82435
• Milind N, Burnham KL, Lee W et al. (2022). Multi-omics integration to characterise mechanisms of molecular QTL from a sepsis cohort.

  
  

  DOI:

  
  

  QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/82436
• Niemi MEK, Karjalainen J, Liao RG et al. (2021). Mapping the human genetic architecture of COVID-19.

  
  

  DOI: 10.1038/s41586-021-03767-x

  
  

  QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/75755
• Pairo-Castineira E, Clohisey S, Klaric L et al. (2021). Genetic mechanisms of critical illness in COVID-19..

  
  

  DOI: 10.1038/s41586-020-03065-y

  
  

  QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/70806

Collaborators

External

• Professor Julian Knight (Wellcome Trust Centre for Human Genomics, Oxford)
• Professor Tony Gordon (Imperial College)
• Dr Emma Davenport (Sanger Institute, Cambridge)
• Dr Kate Burnham (Sanger Institute, Cambridge)