Professor Charles HindsProfessor (Emeritus) and Consultant in Intensive Care MedicineCentre: Translational Medicine and TherapeuticsEmail: c.j.hinds@qmul.ac.ukTelephone: +44(0) 20 3765 8878ProfileResearchPublicationsCollaboratorsProfileCharles Hinds qualified at St. Bartholomew’s Hospital in 1972 and was appointed as Consultant and Senior Lecturer in Anaesthesia and Intensive Care at the same hospital in 1980. Subsequently, he was Director of the Intensive Unit at Barts, and later for the combined Barts and The London NHS Trust, for more than 15 years. He is a past President of the Intensive Care Society and was Chairman of Examiners for the UK Diploma of Intensive Care. He was UK Representative for the European Society of Intensive Care Medicine and a member of the Education and Training Subcommittee of the ESICM. He was for many years a member of the Research Committee of the Intensive Care Society. In January 2007 Professor Hinds was awarded a College Medal by the Royal College of Anaesthetists as a mark of distinction for his work in helping the College to achieve its aims and for his support for the speciality. He was subsequently invited to deliver the Samuel Thompson Rowling oration at the College. In 2013 Prof. Hinds was awarded Honorary Lifetime Memberships of the ESICM and UK Intensive Care Society. Together with Prof. Watson, Professor Hinds has published three editions of their popular textbook: Intensive Care: A concise textbook. Professor Hinds was recently awarded a Gold Medal by the Faculty of Intensive Care Medicine. Memberships and awards Honorary Lifetime Member of the European Society of Intensive Care Medicine and the UK Intensive Care Society Royal College of Anaesthetists College Medal Gold Medal of the Faculty of Intensive Care Medicine ResearchCritical Care and Perioperative Medicine Research Group Group members Professor Gareth Ackland Professor Mark Griffiths Professor Rupert Pearse Dr John Prowle Dr Zudin Pulthucheary Dr Parjam Zolfaghari Dr Alastair Proudfoot Summary Professor Hinds’ research interests have included the pathophysiology and treatment of sepsis, “goal-directed” haemodynamic therapy, endocrine aspects of critical illness, critical illness polyneuromyopathy and intensive care for patients with malignancy. Professor Hinds helped to establish the UK Critical Care Genomics Group which has recently completed a large National investigation (ukccggains.com), as well as being National Co-ordinator for the European “GenOSept” study (ESICM). Currently the group focusses on “multi-omic” approaches to the investigation of sepsis (GAinS2/Sepsis Immunomics), recently including COVID. Other current research interests include the host response to high-risk surgery. Publications Antcliffe DB, Mi Y, Santhakumaran S et al. (2024). Patient stratification using plasma cytokines and their regulators in sepsis: relationship to outcomes, treatment effect and leucocyte transcriptomic subphenotypes. nameOfConference DOI: 10.1136/thorax-2023-220538 QMRO: qmroHref Torrance HD, Zhang P, Longbottom ER et al. (2024). A Transcriptomic Approach to Understand Patient Susceptibility to Pneumonia After Abdominal Surgery. nameOfConference DOI: 10.1097/sla.0000000000006050 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/89968 Kwok AJ, Allcock A, Ferreira RC et al. (2023). Neutrophils and emergency granulopoiesis drive immune suppression and an extreme response endotype during sepsis. nameOfConference DOI: 10.1038/s41590-023-01490-5 QMRO: qmroHref Cano-Gamez E, Burnham KL, Goh C et al. (2022). An immune dysfunction score for stratification of patients with acute infection based on whole-blood gene expression. nameOfConference DOI: 10.1126/scitranslmed.abq4433 QMRO: qmroHref Baillie JK, Begg C, Clohisey Hendry S et al. (2022). Whole-genome sequencing reveals host factors underlying critical COVID-19. nameOfConference DOI: 10.1038/s41586-022-04576-6 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/80960 Consortium CM-OBA, Ahern DJ, Ai Z et al. (2022). A blood atlas of COVID-19 defines hallmarks of disease severity and specificity. nameOfConference DOI: 10.1016/j.cell.2022.01.012 QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/82435 Milind N, Burnham KL, Lee W et al. (2022). Multi-omics integration to characterise mechanisms of molecular QTL from a sepsis cohort. nameOfConference DOI: doi QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/82436 Niemi MEK, Karjalainen J, Liao RG et al. (2021). Mapping the human genetic architecture of COVID-19. nameOfConference DOI: 10.1038/s41586-021-03767-x QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/75755 Pairo-Castineira E, Clohisey S, Klaric L et al. (2021). Genetic mechanisms of critical illness in COVID-19.. nameOfConference DOI: 10.1038/s41586-020-03065-y QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/70806 Smith A, Edlin J, Hinds C et al. (2020). Coronary revascularisation in cardiac amyloidosis. nameOfConference DOI: 10.1111/jocs.14985 QMRO: qmroHref Goh C, Burnham KL, Ansari MA et al. (publicationYear). Epstein-Barr virus reactivation in sepsis due to community-acquired pneumonia is associated with increased morbidity and an immunosuppressed host transcriptomic endotype. nameOfConference DOI: 10.1038/s41598-020-66713-3 QMRO: qmroHref Bangash MN, Abbott TEF, Patel NSA et al. (2020). The Effect of β2-Adrenoceptor Agonists on Leucocyte-Endothelial Adhesion in a Rodent Model of Laparotomy and Endotoxemia. nameOfConference DOI: 10.3389/fimmu.2020.01001 QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/67641 Tridente A, Holloway PAH, Hutton P et al. (2019). Methodological challenges in European ethics approvals for a genetic epidemiology study in critically ill patients: the GenOSept experience. nameOfConference DOI: 10.1186/s12910-019-0370-1 QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/59107 Antcliffe DB, Burnham KL, Al-Beidh F et al. (2019). Transcriptomic Signatures in Sepsis and a Differential Response to Steroids. From the VANISH Randomized Trial. nameOfConference DOI: 10.1164/rccm.201807-1419oc QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/58624 TORRANCE H, LONGBOTTOM R, VIVIAN M et al. (2018). Post-operative immune suppression is mediated via reversible, Interleukin-10 dependent pathways in circulating monocytes following major abdominal surgery. nameOfConference DOI: 10.1371/journal.pone.0203795 QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/45023 Jones TF, Torrance HDT, Owen HC et al. (2018). MicroRNA profiles are associated with lymphocyte count after a major traumatic injury: a potential role for immunometabolism?. nameOfConference DOI: 10.1016/j.bja.2018.05.027 QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/45685 Lashin HMS, Nadkarni S, Oggero S et al. (2018). Microvesicle Subsets in Sepsis Due to Community Acquired Pneumonia Compared to Faecal Peritonitis.. nameOfConference DOI: 10.1097/SHK.0000000000000989 QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/44531 Sweeney TE, Perumal TM, Henao R et al. (publicationYear). A community approach to mortality prediction in sepsis via gene expression analysis. nameOfConference DOI: 10.1038/s41467-018-03078-2 QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/58622 Annane D, Mira J-P, Ware LB et al. (2018). Pharmacogenomic biomarkers do not predict response to drotrecogin alfa in patients with severe sepsis. nameOfConference DOI: 10.1186/s13613-018-0353-2 QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/58138 Tridente A, Bion J, Mills GH et al. (2017). Derivation and validation of a prognostic model for postoperative risk stratification of critically ill patients with faecal peritonitis. nameOfConference DOI: 10.1186/s13613-017-0314-1 QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/58629 Scicluna BP, van Vught LA, Zwinderman AH et al. (2017). Classification of patients with sepsis according to blood genomic endotype: a prospective cohort study. nameOfConference DOI: 10.1016/s2213-2600(17)30294-1 QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/58625 Burnham KL, Davenport EE, Radhakrishnan J et al. (2017). Shared and Distinct Aspects of the Sepsis Transcriptomic Response to Fecal Peritonitis and Pneumonia. nameOfConference DOI: 10.1164/rccm.201608-1685oc QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/58630 Bos L, Schouten L, van Vught L et al. (publicationYear). ESICM LIVES 2016: part one. nameOfConference DOI: 10.1186/s40635-016-0098-x QMRO: qmroHref Scherag A, Schöneweck F, Kesselmeier M et al. (2016). Genetic Factors of the Disease Course after Sepsis: A Genome-Wide Study for 28Day Mortality. nameOfConference DOI: 10.1016/j.ebiom.2016.08.043 QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/58621 Sivakumar S, Taccone FS, Desai KA et al. (2016). ESICM LIVES 2016: part two : Milan, Italy. 1-5 October 2016.. ESICM Lives 2016 DOI: 10.1186/s40635-016-0099-9 QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/16157 Longbottom ER, Torrance HDT, Owen HC et al. (2016). Features of Postoperative Immune Suppression Are Reversible With Interferon Gamma and Independent of Interleukin-6 Pathways. nameOfConference DOI: 10.1097/sla.0000000000001484 QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/11890 Davenport EE, Burnham KL, Radhakrishnan J et al. (2016). Genomic landscape of the individual host response and outcomes in sepsis: a prospective cohort study. nameOfConference DOI: 10.1016/s2213-2600(16)00046-1 QMRO: qmroHref Tridente A, Clarke GM, Walden A et al. (2015). Association between trends in clinical variables and outcome in intensive care patients with faecal peritonitis: analysis of the GenOSept cohort. nameOfConference DOI: 10.1186/s13054-015-0931-8 QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/58737 Owen HC, Torrance HDT, Jones TF et al. (2015). Epigenetic regulatory pathways involving microRNAs may modulate the host immune response following major trauma. nameOfConference DOI: 10.1097/ta.0000000000000850 QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/8032 Raja M, Torrance H, Longbottom E et al. (2015). Long-Term Follow-Up of Sepsis Induced Immunoparalysis. nameOfConference DOI: 10.1186/2197-425x-3-s1-a49 QMRO: qmroHref Longbottom E, Torrance H, Owen H et al. (2015). Post-operative immune suppression is reversible with interferon gamma and independent of IL-6 pathways. nameOfConference DOI: 10.1186/2197-425x-3-s1-a820 QMRO: qmroHref Torrance H, Brohi K, Warnes G et al. (2015). T-helper cell polarisation following severe polytrauma. nameOfConference DOI: 10.1186/2197-425x-3-s1-a848 QMRO: qmroHref Owen H, Torrance H, Barnes M et al. (2015). The Role of Micrornas in The Development of Hospital Acquired Infection in Polytrauma Patients. nameOfConference DOI: 10.1186/2197-425x-3-s1-a35 QMRO: qmroHref Jones TF, Owen HC, Torrance HD et al. (2015). MicroRNA-mediated regulation of IL-10, IL-12 and TNFα gene expression in severely injured trauma patients. nameOfConference DOI: 10.1186/1757-7241-23-s2-o5 QMRO: qmroHref Rautanen A, Chapman SJ, Hinds CJ (2015). Response to Schöneweck et al.: Common genomic variation in the FER gene: useful to stratify patients with sepsis due to pneumonia?. nameOfConference DOI: 10.1007/s00134-015-3893-z QMRO: qmroHref Mills TC, Chapman S, Hutton P et al. (2015). Variants in the Mannose-binding Lectin Gene MBL2 do not Associate With Sepsis Susceptibility or Survival in a Large European Cohort. nameOfConference DOI: 10.1093/cid/civ378 QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/58631 Torrance HD, Brohi K, Pearse RM et al. (2015). Association between gene expression biomarkers of immunosuppression and blood transfusion in severely injured polytrauma patients. nameOfConference DOI: 10.1097/SLA.0000000000000653 QMRO: qmroHref Torrance HD, Brohi K, Pearse RM et al. (2015). Association between gene expression biomarkers of immunosuppression and blood transfusion in severely injured polytrauma patients.. nameOfConference DOI: 10.1097/SLA.0000000000000653 QMRO: qmroHref Tridente A, Clarke G, Walden A et al. (2015). Phenotypic factors associated with outcome in 977 intensive care patients with faecal peritonitis: analysis of trends in the GenOSept cohort. nameOfConference DOI: 10.1186/cc14108 QMRO: qmroHref Torrance HD, Vivian ME, Brohi K et al. (2015). Changes in gene expression following trauma are related to the age of transfused packed red blood cells. nameOfConference DOI: 10.1097/TA.0000000000000534 QMRO: qmroHref Rautanen A, Mills TC, Gordon AC et al. (2015). Genome-wide association study of survival from sepsis due to pneumonia: an observational cohort study. nameOfConference DOI: 10.1016/s2213-2600(14)70290-5 QMRO: qmroHref MacDonald N, Ahmad T, Mohr O et al. (2015). Dynamic preload markers to predict fluid responsiveness during and after major gastrointestinal surgery: an observational substudy of the OPTIMISE trial. nameOfConference DOI: 10.1093/bja/aeu398 QMRO: qmroHref Owen H, Torrance H, Brohi K et al. (2014). 1068. MicroRNA-regulated immunosuppression in severely injured polytrauma patients. nameOfConference DOI: 10.1186/2197-425x-2-s1-p84 QMRO: qmroHref Torrance HD, Brohi K, Pearse RM et al. (2014). Association between gene expression biomarkers of immunosuppression and blood transfusion in severely injured polytrauma patients. nameOfConference DOI: 10.1186/1757-7241-22-s1-o7 QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/12107 Pearse RM, Harrison DA, MacDonald N et al. (2014). Effect of a perioperative, cardiac output-guided hemodynamic therapy algorithm on outcomes following major gastrointestinal surgery: a randomized clinical trial and systematic review.. nameOfConference DOI: 10.1001/jama.2014.5305 QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/11483 Fragkou P, Torrance H, Ackland G et al. (2014). Major gastrointestinal surgery is associated with a specific gene expression profile that is quantitatively associated with infectious complications. nameOfConference DOI: 10.1097/00003643-201406001-00037 QMRO: qmroHref Fragkou P, Prowle J, Ackland G et al. (2014). Perioperative blood transfusion is associated with a characteristic immune response, excess infectious complications and death in patients undergoing scheduled major gastrointestinal surgery. nameOfConference DOI: 10.1097/00003643-201406001-00249 QMRO: qmroHref O'Leary MJ, Quinton N, Ferguson CN et al. (2000). In rats with sepsis, the acute fall in IGF-I is associated with an increase in circulating growth hormone-binding protein levels. nameOfConference DOI: 10.1007/s001340000656 QMRO: qmroHref Mills TC, Rautanen A, Elliott KS et al. (2014). IFITM3 and Susceptibility to Respiratory Viral Infections in the Community. nameOfConference DOI: 10.1093/infdis/jit468 QMRO: qmroHref Lashin H, Nadkarni S, Hinds C et al. (2014). IN PATIENTS WITH SEVERE SEPSIS MICROPARTICLE PROFILES DIFFER ACCORDING TO THE SOURCE OF INFECTION. nameOfConference DOI: doi QMRO: qmroHref Dalli J, Norling LV, Montero-Melendez T et al. (2014). Microparticle alpha-2-macroglobulin enhances pro-resolving responses and promotes survival in sepsis.. nameOfConference DOI: 10.1002/emmm.201303503 QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/10756 Walden AP, Clarke GM, McKechnie S et al. (2014). Patients with community acquired pneumonia admitted to European intensive care units: an epidemiological survey of the GenOSept cohort. nameOfConference DOI: 10.1186/cc13812 QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/58632 Tridente A, Clarke GM, Walden A et al. (2014). Patients with faecal peritonitis admitted to European intensive care units: an epidemiological survey of the GenOSept cohort. nameOfConference DOI: 10.1007/s00134-013-3158-7 QMRO: qmroHref Fragkou PC, Torrance HD, Pearse RM et al. (2014). Perioperative blood transfusion is associated with a gene transcription profile characteristic of immunosuppression: a prospective cohort study. nameOfConference DOI: 10.1186/s13054-014-0541-x QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/12111 Vivian M, Torrance HDT, Pearse R et al. (2014). THE AGE OF TRANSFUSED PACKED RED BLOOD CELLS CORRELATES WITH THE DEGREE OF IMMUNOSUPPRESSION AS ASSESSED BY GENE EXPRESSION PATTERNS IN SEVERELY INJURED TRAUMA PATIENTS. nameOfConference DOI: doi QMRO: qmroHref Dalli J, Montero-Melendez T, Norling LV et al. (2013). Heterogeneity in neutrophil microparticles reveals distinct proteome and functional properties.. nameOfConference DOI: 10.1074/mcp.M113.028589 QMRO: qmroHref Bangash MN, Patel NSA, Benetti E et al. (2013). Dopexamine can attenuate the inflammatory response and protect against organ injury in the absence of significant effects on hemodynamics or regional microvascular flow.. nameOfConference DOI: 10.1186/cc12585 QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/4380 Torrance H, Brohi K, Hinds C et al. (2013). Cytokine gene expression can predict infectious complications following severe trauma. nameOfConference DOI: 10.1186/cc11965 QMRO: qmroHref Torrance HDT, Brohi K, Pearse RM et al. (2013). BLOOD TRANSFUSION FOLLOWING SEVERE TRAUMA IS ASSOCIATED WITH THE DEVELOPMENT OF AN EARLY ANTI-INFLAMMATORY RESPONSE. nameOfConference DOI: doi QMRO: qmroHref Perretti M, Dalli J, Norling LV et al. (2013). Neutrophil Microparticles are heterogenous in content and function. nameOfConference DOI: 10.1096/fasebj.27.1_supplement.138.5 QMRO: qmroHref Evans SF, Hinds CJ, Varley JG (1984). A new canine model of endotoxin shock. nameOfConference DOI: 10.1111/j.1476-5381.1984.tb16504.x QMRO: qmroHref Evans SF, Hinds CJ, Varley JG (1984). Effects of intravascular volume expansion on the cardiovascular response to naloxone in a canine model of severe endotoxin shock. nameOfConference DOI: 10.1111/j.1476-5381.1984.tb16505.x QMRO: qmroHref Ghosh IR, Kennedy DD, Fletcher SN et al. (2001). Identical persisting neurophysiological features of chronic denervation found in four cases of resolved critical illness motor syndrome. nameOfConference DOI: 10.3109/tcic.12.5-6.229.236 QMRO: qmroHref Myers K, Hajek P, Hinds C et al. (2011). Stopping smoking shortly before surgery and postoperative complications: a systematic review and meta-analysis.. nameOfConference DOI: 10.1001/archinternmed.2011.97 QMRO: qmroHref Radhakrishinan J, Svoren EM, Ellis P et al. (2011). A FUNCTIONAL GENOMICS APPROACH TO THE IDENTIFICATION OF BR :MARKERS OF SURVIVAL IN SEVERE SEPSIS DUE TO COMMUNITY ACQUIRED PNEUMONIA. nameOfConference DOI: doi QMRO: qmroHref Tridente A, Clarke GM, Walden A et al. (2011). EPIDEMIOLOGY OF FAECAL PERITONITIS IN THE GENOSEPT COHORT. nameOfConference DOI: doi QMRO: qmroHref Svoren EM, Radhakrisnan J, Ellis P et al. (2011). GLOBAL GENE EXPRESSION PROFILING REVEALS KEY PATHWAYS ASSOCIATED WITH THE HOST RESPONSE TO CARDIAC SURGERY AND CARDIOPULMONARY BYPASS. nameOfConference DOI: doi QMRO: qmroHref Walden AP, Clarke G, McKechnie S et al. (2010). EPIDEMIOLOGY OF COMMUNITY ACQUIRED PENUMONIA IN THE GENOSEPT COHORT. nameOfConference DOI: doi QMRO: qmroHref Jhanji S, Vivian-Smith A, Lucena-Amaro S et al. (2010). A randomised controlled trial of the effects of three haemodynamic therapies on microvascular flow, tissue oxygenation and inflammatory markers after major abdominal surgery.. The Intensive Care Society State of the Art Meeting DOI: doi QMRO: qmroHref Bangash MN, Patel NS, Hinds CJ et al. (2010). Dose-dependent effects of dopexamine on indices of shock and organ dysfunction in a rodent model of laparotomy and endoxaemia.. The Intensive Care Society State of the Art Meeting DOI: doi QMRO: qmroHref Radhakrishnan J, Svoren E, Ellis P et al. (2010). Evolution of gene expression signatures in septic shock due to community-acquired pneumonia.. The Intensive Care Society State of The Art Meeting DOI: doi QMRO: qmroHref Jhanji S, Vivian-Smith A, Lucena-Amaro S et al. (2010). Haemodynamic optimisation improves tissue microvascular flow and oxygenation after major surgery: a randomised controlled trial.. nameOfConference DOI: 10.1186/cc9220 QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/11486 Svoren E, Radhakrishnan J, Ellis P et al. (2010). Sequential gene expression profiles following cardiac surgery involving cardiopulmonary bypass.. The Intensive Care Society State of the Art Meeting DOI: doi QMRO: qmroHref Pearse R, Bennett D, Hinds C (2009). Dopexamine and survival: areas of consistency. nameOfConference DOI: 10.1111/j.1365-2044.2009.06111.x QMRO: qmroHref Jhanji S, Vivian-Smith A, Lucena-Amaro S et al. (2009). A RANDOMISED CONTROLLED TRIAL OF THE EFFECTS OF POST-OPERATIVE HAEMODYNAMIC OPTIMISATION ON MICROVASCULAR FLOW, TISSUE OXYGENATION AND INFLAMMATORY MARKERS AFTER MAJOR ABDOMINAL SURGERY. nameOfConference DOI: doi QMRO: qmroHref Hinds CJ, Watson D (2009). Intensive Care Medicine. nameOfConference DOI: doi QMRO: qmroHref Jhanji S, Stirling S, Patel N et al. (2009). The effect of increasing doses of norepinephrine on tissue oxygenation and microvascular flow in patients with septic shock.. nameOfConference DOI: 10.1097/CCM.0b013e3181a00a1c QMRO: qmroHref Jhanji S, Lee C, Watson D et al. (2009). Microvascular flow and tissue oxygenation after major abdominal surgery: association with post-operative complications.. nameOfConference DOI: 10.1007/s00134-008-1325-z QMRO: qmroHref Jhanji S, Lee C, Watson D et al. (2009). Alterations in microvascular flow and tissue oxygenation after major abdominal surgery.. The Intensive Care Society State of the Art Meeting DOI: 10.1007/s00134-008-1325-z QMRO: qmroHref Maddison B, Wolff C, Findlay G et al. (2009). Comparison of three methods of extravascular lung water volume measurement in patients after cardiac surgery.. nameOfConference DOI: 10.1186/cc7948 QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/11481 Jhanji S, Stirling S, Patel NSA et al. (2009). EFFECT OF INCREASING DOSES OF NOREPINEPHRINE ON TISSUE OXYGENATION AND MICROVASCULAR PERFUSION IN SEPTIC SHOCK. nameOfConference DOI: doi QMRO: qmroHref Jhanji S, Stirling S, Patel N et al. (2009). Effect of increasing doses of noradrenaline on microvascular perfusion and tissue oxygenation in septic shock.. The Intensive Care Society State of the Art Meeting DOI: 10.1097/CCM.0b013e3181a00a1c QMRO: qmroHref Agha-Jaffar R, Hinds CJ (2009). Growth hormone and multiple organ dysfunction syndrome.. nameOfConference DOI: doi QMRO: qmroHref Maddison B, Giudici R, Calzia E et al. (2008). Extravascular lung water volume measurement by a novel lithium-thermal indicator dilution method: comparison of three techniques to post-mortem gravimetry.. nameOfConference DOI: 10.1007/s00134-008-1207-4 QMRO: qmroHref Hinds CJ, Watson D (2008). Intensive Care: A Concise Textbook. nameOfConference DOI: doi QMRO: qmroHref Eisen DP, Dean MM, Boermeester MA et al. (2008). Low serum mannose-binding lectin level increases the risk of death due to pneumococcal infection. nameOfConference DOI: 10.1086/590006 QMRO: qmroHref Jhanji S, Thomas B, Ely A et al. (2008). Mortality and utilisation of critical care resources amongst high-risk surgical patients in a large NHS trust.. nameOfConference DOI: 10.1111/j.1365-2044.2008.05560.x QMRO: qmroHref Gordon A, Knight JC, Hinds CJ (2008). Genes and sepsis: How tight is the fit?. nameOfConference DOI: 10.1097/CCM.0b013e318170f358 QMRO: qmroHref Maddison B, Wolff C, Findlay G et al. (2008). Intrathoracic blood volume measurement: comparison of transpulmonary lithium indicator dilution with indocyanine green indicator dilution. nameOfConference DOI: 10.1186/cc6324 QMRO: qmroHref Jhanji S, Stirling S, Patel N et al. (2008). Alterations in tissue oxygenation and microvascular flow during and after major abdominal surgery.. European Society of Intensive Care Medicine 21st Annual Congress DOI: doi QMRO: qmroHref Yasin M, Sivarajah A, Klaus R et al. (2008). Clondine Pre-treatment inhibits mitochondrial kapt channels and modulates the cardaic transcriptome to augment acute myocardial ischaemia reperfusion injury: A biphasic response.. European Society of Intensive Care Medicine 21st Annual Congress DOI: doi QMRO: qmroHref Maddison B, Findlay G, Radermacher P et al. (2008). Intrathoracic blood volume measurement: A comparison of transpulmonary lithium indicator dilution with indocyanine green indicator dilution. nameOfConference DOI: doi QMRO: qmroHref Ravic N, Tucker AT, Wareham DW et al. (2007). A study of novel oxides of nitrogen generating solution to prevent microbial colonization and ventilator associated pneumonia (VAP). nameOfConference DOI: doi QMRO: qmroHref Hadley JS, Wang JE, Michaels LC et al. (2007). Alterations in inflammatory capacity and TLR expression on monocytes and neutrophils after cardiopulmonary bypass.. nameOfConference DOI: 10.1097/01.shk.0000245033.69977.c5 QMRO: qmroHref Maddison B, Best T, Wolff C et al. (2007). Transpulmonary lithium indicator dilution: a new method of intrathoracic blood volume measurement. nameOfConference DOI: 10.1186/cc5455 QMRO: qmroHref Hinds CJ (1987). A way forward for intensive care. nameOfConference DOI: 10.1111/j.1365-2044.1987.tb04055.x QMRO: qmroHref Sury MRJ, Hinds CJ, Boustred M (1986). Accidental discomexion following inactivation of Servoventilator alarm. nameOfConference DOI: 10.1111/j.1365-2044.1986.tb12727.x QMRO: qmroHref HINDS CJ, ELLIS RH, SALOOJEE Y (1978). Blood levels of nitrous oxide during bronchoscopy. nameOfConference DOI: 10.1111/j.1365-2044.1978.tb08494.x QMRO: qmroHref HINDS CJ (1982). Current management of patients after cardiopulmonary bypass. nameOfConference DOI: 10.1111/j.1365-2044.1982.tb01058.x QMRO: qmroHref WATSON JD, FERGUSON C, HINDS CJ et al. (1993). Exertional heat stroke induced by amphetamine analogues. nameOfConference DOI: 10.1111/j.1365-2044.1993.tb07526.x QMRO: qmroHref Ellis RH, Hinds CJ (1977). Management of anaesthesia during tracheal resection. nameOfConference DOI: 10.1111/j.1365-2044.1977.tb11660.x QMRO: qmroHref THOMAS DJB, HINDS CJ, REES GM (1983). The management of insulin dependent diabetes during cardiopulmonary bypass and general surgery. nameOfConference DOI: 10.1111/j.1365-2044.1983.tb12478.x QMRO: qmroHref Hinds CJ, Willatts SM (1984). Training in intensive care. nameOfConference DOI: 10.1111/j.1365-2044.1984.tb07249.x QMRO: qmroHref Garrard CS, Hinds CJ, Knight JC (2007). Applications in critical care medicine. nameOfConference DOI: doi QMRO: qmroHref Murch O, Collin M, Hinds CJ et al. (2007). Lipoproteins in inflammation and sepsis. I. Basic science. nameOfConference DOI: 10.1007/s00134-006-0432-y QMRO: qmroHref HINDS CJ, Thiermermann C, Foster SJ et al. (2006). Alterations in inflammatory capacity and TLR expression on monocytes and neutrophils following cardiopulmonary bypass. nameOfConference DOI: doi QMRO: qmroHref Pearse RM, Harrison DA, James P et al. (2006). Identification and characterisation of the high-risk surgical population in the United Kingdom. nameOfConference DOI: 10.1186/cc4928 QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/9888 Gordon AC, Waheed U, Hansen TK et al. (2006). Mannose-binding lectin polymorphisms in severe sepsis: relationship to levels, incidence, and outcome.. nameOfConference DOI: 10.1097/01.shk.0000186928.57109.8d QMRO: qmroHref Pearse RM, Hinds CJ (2006). Should we use central venous saturation to guide management in high-risk surgical patients?. nameOfConference DOI: 10.1186/cc5122 QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/11479 Teng Chung T, Hinds CJ (2006). Treatment with GH and IGF-1 in critical illness.. nameOfConference DOI: 10.1016/j.ccc.2005.09.003 QMRO: qmroHref Hadley JS, Wang JE, Foster SJ et al. (2005). Peptidoglycan of Staphylococcus aureus upregulates monocyte expression of CD14, toll-like receptor 2 (TLR2), and TLR4 in human blood: Possible implications for priming of lipopolysaccharide signaling. nameOfConference DOI: 10.1128/IAI.73.11.7613-7619.2005 QMRO: qmroHref Gordon AC, Oakervee HE, Kaya B et al. (2005). Incidence and outcome of critical illness amongst hospitalised patients with haematological malignancy: a prospective observational study of ward and intensive care unit based care.. nameOfConference DOI: 10.1111/j.1365-2044.2005.04139.x QMRO: qmroHref Gordon AC, Oakervee HE, Kaya B et al. (2005). Incidence and outcome of critical illness amongst hospitalised patients with haematological malignancy: a prospective observational study of ward and intensive care unit based care.. nameOfConference DOI: 10.1111/j.1365-2044.2005.04139.x QMRO: qmroHref Hinds CJ, Watson JD (2005). Intensive Care Medicine. nameOfConference DOI: doi QMRO: qmroHref Hadley JS, Wang JE, Michaels LC et al. (2005). The effect of cardiopulmonary bypass (CPB) on monocyte receptor expression and ex vivo cytokine production.. nameOfConference DOI: doi QMRO: qmroHref Botfield C, Hinds CJ (1999). Growth Hormone and IGF-I as Anabolic Therapy. nameOfConference DOI: 10.1159/000061012 QMRO: qmroHref Gordon AC, Lagan AL, Aganna E et al. (2004). TNF and TNFR polymorphisms in severe sepsis and septic shock: a prospective multicentre study. nameOfConference DOI: 10.1038/sj.gene.6364136 QMRO: qmroHref Carlet J, Thijs LG, Antonelli M et al. (2004). Challenges in end-of-life care in the ICU - Statement of the 5th International Consensus Conference in Critical Care: Brussels, Belgium, April 2003. nameOfConference DOI: 10.1007/s00134-004-2241-5 QMRO: qmroHref Wu AH, Hinds CJ, Thiemermann C (2004). High-density lipoproteins in sepsis and septic shock: Metabolism, actions, and therapeutic applications. nameOfConference DOI: 10.1097/01.shk.0000111661.09279.82 QMRO: qmroHref Hadley JS, Wang JE, Foster SJ et al. (2004). Cytokine responses to combined administration of lipopolysaccharide (LPS) and peptidoglycan (PepG). nameOfConference DOI: 10.1097/00024382-200403001-00197 QMRO: qmroHref HINDS CJ, Carle J, Thijs LG et al. (2004). International Consensus Conference on challenges in end of life care. Statement of the 5th International Consensus Conference in Critical Care. nameOfConference DOI: doi QMRO: qmroHref Hadley JS, Wang JE, Foster SJ et al. (2004). Monocyte cell surface receptor upregulation in response to stimulation with lipopolysaccharide and peptidoglycan. nameOfConference DOI: 10.1097/00024382-200403001-00084 QMRO: qmroHref O'Leary MJ, Koll M, Ferguson CN et al. (2003). Liver albumin synthesis in sepsis in the rat: influence of parenteral nutrition, glutamine and growth hormone.. nameOfConference DOI: 10.1042/CS20030128 QMRO: qmroHref McDonald MC, Dhadly P, Cockerill GW et al. (2003). Reconstituted high-density lipoprotein attenuates organ injury and adhesion molecule expression in a rodent model of endotoxic shock. nameOfConference DOI: 10.1097/01.shk.0000097249.97298.a3 QMRO: qmroHref Fletcher SN, Kennedy DD, Ghosh IR et al. (2003). Persistent neuromuscular and neurophysiologic abnormalities in long-term survivors of prolonged critical illness. nameOfConference DOI: 10.1097/01.CCM.0000053651.38421.D9 QMRO: qmroHref Peters CJ, Aganna E, Nanjee MN et al. (2003). Relationship of paraoxonase 1 R/Q polymorphism to outcome from severe sepsis and septic shock. nameOfConference DOI: doi QMRO: qmroHref Makings E, Hinds CJ (2003). Monitoring. nameOfConference DOI: 10.1007/978-1-84800-145-9_17 QMRO: qmroHref McDonald MC, Dhadly P, Cockerill GW et al. (2003). Reconstituted high-density lipoprotein attenuates organ injury and adhesion molecule expression in a rodent model of endotoxic shock.. nameOfConference DOI: doi QMRO: qmroHref Hadley JS, Hinds CJ (2002). Anabolic strategies in critical illness. nameOfConference DOI: 10.1016/s1471-4892(02)00217-5 QMRO: qmroHref Oakervee HE, Gordon AC, Kaya B et al. (2002). Outcomes of critical illness in patients with haematological malignancy.. nameOfConference DOI: doi QMRO: qmroHref Gordon AC, Oakervee HE, Kaya B et al. (2002). A prospective study of the incidence and outcome of critical illness in a haemato-oncology unit. nameOfConference DOI: doi QMRO: qmroHref O'Leary MJ, Ferguson CN, Coakley JH et al. (2002). Influence of starvation, surgery, and sepsis on cardiac protein synthesis in rats: Effects of parenteral nutrition, glutamine, and growth hormone. nameOfConference DOI: 10.1097/00024382-200209000-00011 QMRO: qmroHref Gordon AC, Cheung L, Aganna E et al. (2002). Lack of association between the-308 TNF promoter polymorphism & outcome from sepsis & septic shock. nameOfConference DOI: doi QMRO: qmroHref Peters CJ, Nanjee MN, Gordon AC et al. (2002). Modification of High Density Lipoprotein in septic shock: relationship to outcome. nameOfConference DOI: doi QMRO: qmroHref Gordon AC, Aganna E, Cheung L et al. (2002). Polymorphisms of the TNFRSF1B gene: Relationship to outcome from severe sepsis and septic shock. nameOfConference DOI: doi QMRO: qmroHref Gordon AC, Aganna E, Cheung L et al. (2002). TNF RECEPTOR POLYMORPHISMS: RELATIONSHIP TO OUTCOME FROM SEVERE SEPSIS AND SEPTIC SHOCK. nameOfConference DOI: 10.1097/00024382-200209001-00022 QMRO: qmroHref Makings EA, Beddow ECL, Wilkes M et al. (2002). Decreased intragastric production of nitric oxide could predispose to ventilator-associated pneumonia. nameOfConference DOI: doi QMRO: qmroHref Peters CJ, Nanjee MN, Gordon AC et al. (2002). Proinflammatory modifications of lipoprotein structure and function in patients with septic shock: relationship to outcome. nameOfConference DOI: doi QMRO: qmroHref O'Leary MJ, Ferguson CN, Rennie M et al. (2002). Effect of growth hormone on muscle and liver protein synthesis in septic rats receiving glutamine-enriched parenteral nutrition. nameOfConference DOI: 10.1097/00003246-200205000-00023 QMRO: qmroHref Smith PJ, Spurrell EL, Coakley J et al. (2002). An exonic splicing enhancer in human IGF-I pre-mRNA mediates recognition of alternative exon 5 by the serine-arginine protein splicing factor-2/alternative splicing factor. nameOfConference DOI: 10.1210/endo.143.1.8598 QMRO: qmroHref Hinds CJ, Watson JD (2002). Intensive Care Medicine. nameOfConference DOI: doi QMRO: qmroHref Hinds CJ (2001). Treatment of sepsis with activated protein C - Encouraging news for well selected patients. nameOfConference DOI: 10.1136/bmj.323.7318.881 QMRO: qmroHref O'Leary MJ, Koll M, Ferguson CN et al. (2001). Influence of nutrition, glutamine and growth hormone on skeletal muscle protease activity in septic rats. nameOfConference DOI: doi QMRO: qmroHref O'Leary MJ, Ferguson CN, Rennie MJ et al. (2001). Sequential changes in in vivo muscle and liver protein synthesis and plasma and tissue glutamine levels in sepsis in the rat. nameOfConference DOI: 10.1042/cs1010295 QMRO: qmroHref O'Leary MJ, Koll M, Ferguson CN et al. (2001). Skeletal muscle lysosomal protease activity in septic rats. nameOfConference DOI: doi QMRO: qmroHref Johnson TS, O'Leary M, Justice SK et al. (2001). Differential expression of suppressors of cytokine signalling genes in response to nutrition and growth hormone in the septic rat. nameOfConference DOI: 10.1677/joe.0.1690409 QMRO: qmroHref Wray GM, Foster SJ, Hinds CJ et al. (2001). A cell wall component from pathogenic and non-pathogenic gram-positive bacteria (peptidoglycan) synergises with endotoxin to cause the release of tumour necrosis factor-alpha, nitric oxide production, shock, and multiple organ injury/dysfunction in the rat. nameOfConference DOI: 10.1097/00024382-200115020-00010 QMRO: qmroHref Ghosh IR, Kennedy DD, Fleter SN et al. (2001). Identical persisting neurophysiological features of chronic denervation found in four cases of resolved critical illness motor syndrome.. nameOfConference DOI: 10.1080/714028772 QMRO: qmroHref Kennedy DD, Fletcher SN, Ghosh IR et al. (2000). Early detection of the covert onset and evolution of critical illness polyneuromyopathy. nameOfConference DOI: 10.1093/bja/84.5.688 QMRO: qmroHref Dhadly P, McDonald MC, Cockerill G et al. (2000). Pre-treatment with high density lipoprotein (HDL) attenuates the renal and hepatic dysfunction caused by endotoxin in rats. nameOfConference DOI: 10.1093/bja/84.5.688-a QMRO: qmroHref Kennedy DD, Fletcher N, Hinds C (2000). Neuromuscular dysfunction in critical illness: what are we dealing with?. nameOfConference DOI: 10.1097/00001503-200004000-00002 QMRO: qmroHref O'Leary M, Koll M, Ferguson C et al. (2000). Parenteral nutrition (PN) depresses hepatic albumin synthesis in septic rats. nameOfConference DOI: 10.1186/cc881 QMRO: qmroHref Botfield C, Hinds CJ (2000). Growth hormone in catabolic illness. nameOfConference DOI: 10.1097/00075197-200003000-00011 QMRO: qmroHref Dhadly P, McDonald M, Cockerill G et al. (2000). High-density lipoprotein (HDL) reduces the renal injury and dysfunction in shock. nameOfConference DOI: doi QMRO: qmroHref Takala J, Hinds CJ (2000). Increased mortality associated with growth hormone treatment in critically ill adults - Reply. nameOfConference DOI: doi QMRO: qmroHref Malik SB, O'Leary M, Grimble GK et al. (2000). The effect of glutamine supplementation on RNA turnover in critically-ill patients.. nameOfConference DOI: doi QMRO: qmroHref Kennedy DD, Fletcher SN, Ghosh IR et al. (1999). Reversible tetraplegia due to polyneuropathy in a diabetic patient with hyperosmolar non-ketotic coma. nameOfConference DOI: 10.1007/s001340051095 QMRO: qmroHref Ferguson C, Coakley J, Koll M et al. (1999). EFFECT OF PARENTERAL FEED WITH OR WITHOUT GLUTAMINE AND GROWTH HORMONE ON SYNTHESIS OF CONTRACTILE AND CYTOPLASMIC PROTEIN IN THE GASTROCNEMIUS MUSCLE OF SEPTIC RATS.. nameOfConference DOI: 10.1097/00024382-199911001-00178 QMRO: qmroHref Ferguson C, Coakley J, Koll M et al. (1999). FRACTIONAL PROTEIN SYNTHESIS RATES IN VIVO OF CONTRACTILE AND CYTOPLASMIC PROTEIN FRACTIONS OF SKELETAL MUSCLE IN THE SEPTIC RAT.. nameOfConference DOI: 10.1097/00024382-199911001-00169 QMRO: qmroHref Takala J, Ruokonen E, Webster NR et al. (1999). Increased Mortality Associated with Growth Hormone Treatment in Critically Ill Adults. nameOfConference DOI: 10.1056/nejm199909093411102 QMRO: qmroHref Hinds CJ, Watson D (1999). Circulatory support. nameOfConference DOI: 10.1136/bmj.318.7200.1749 QMRO: qmroHref Hinds CJ (1999). Administration of growth hormone to catabolic patients. nameOfConference DOI: 10.1016/s1096-6374(99)80014-8 QMRO: qmroHref Griffiths RD, Hinds CJ, Little RA (1999). Manipulating the metabolic response to injury. nameOfConference DOI: 10.1258/0007142991902204 QMRO: qmroHref O’Leary MJ, Timmins AC, Appleby JN et al. (1999). Dissociation of pituitary-adrenal and catecholamine activation after induced cardiac arrest and defibrillation. nameOfConference DOI: 10.1093/bja/82.2.271 QMRO: qmroHref Fletcher SN, Kennedy DD, Ghosh IR et al. (1999). Assessment of neuromuscular function in long-term survivors of prolonged critical illness. nameOfConference DOI: doi QMRO: qmroHref Ghosh IR, Fletcher SN, Kennedy DD et al. (1999). Follow-up EMG in critical illness neuromuscular disorders. nameOfConference DOI: doi QMRO: qmroHref Hinds CJ, Fletcher SN (1999). Ranitidine reduced clinically important gastrointestinal bleeding in patients who required mechanical ventilation. nameOfConference DOI: 10.1136/gut.44.1.10 QMRO: qmroHref Drake WM, Perry LA, Hinds CJ et al. (1998). Emergency and Prolonged Use of Intravenous Etomidate to Control Hypercortisolemia in a Patient with Cushing’s Syndrome and Peritonitis. nameOfConference DOI: 10.1210/jcem.83.10.5156 QMRO: qmroHref Hinds CJ, Martin R, Quinton P (1998). Intensive care for patients with medical complications of haematological malignancy: is it worth it?. nameOfConference DOI: doi QMRO: qmroHref Coakley JH, Nagendran K, Yarwood GD et al. (1998). Patterns of neurophysiological abnormality in prolonged critical illness. nameOfConference DOI: 10.1007/s001340050669 QMRO: qmroHref Wray GM, Hinds CJ, Thiemermann C (1998). EFFECTS OF INHIBITORS OF POLY(ADP-RIBOSE) SYNTHETASE ACTIVITY ON HYPOTENSION AND MULTIPLE ORGAN DYSFUNCTION CAUSED BY ENDOTOXIN. nameOfConference DOI: 10.1097/00024382-199807000-00003 QMRO: qmroHref Wray GM, Millar CG, Hinds CJ et al. (1998). SELECTIVE INHIBITION OF THE ACTIVITY OF INDUCIBLE NITRIC OXIDE SYNTHASE PREVENTS THE CIRCULATORY FAILURE, BUT NOT THE ORGAN INJURY/DYSFUNCTION, CAUSED BY ENDOTOXIN. nameOfConference DOI: 10.1097/00024382-199805000-00003 QMRO: qmroHref Wray GM, Hinds CJ, Thiemermann C (1998). Cell wall fragments from Gram positive and Gram negative bacteria synergize to cause organ failure in the rat. nameOfConference DOI: doi QMRO: qmroHref Wray G, Millar C, Leach M et al. (1998). The selective inhibitor of inducible nitric oxide synthase, 1400W, prevents the circulatory failure but not the organ injury caused by endotoxin in the rat. nameOfConference DOI: doi QMRO: qmroHref Botfield C, Ross RJM, Hinds CJ (1997). The role of IGFs in catabolism. nameOfConference DOI: 10.1016/s0950-351x(97)80958-5 QMRO: qmroHref Ng TTC, Gibson FAM, Nye KE et al. (1997). DESENSITIZATION OF THE INFLAMMATORY RESPONSE IN HUMANS. nameOfConference DOI: 10.1097/00024382-199709000-00002 QMRO: qmroHref Yarwood GD, Ross RJM, Medbak S et al. (1997). Administration of human recombinant insulin-like growth factor-I in critically ill patients. nameOfConference DOI: 10.1097/00003246-199708000-00023 QMRO: qmroHref Hayes MA, Timmins AC, Yau EHS et al. (1997). Oxygen transport patterns in patients with sepsis syndrome or septic shock. nameOfConference DOI: 10.1097/00003246-199706000-00007 QMRO: qmroHref Gibson FAM, Hinds CJ (1997). Growth hormone and insulin- like growth factors in critical illness. nameOfConference DOI: 10.1007/s001340050343 QMRO: qmroHref Rodríguez-Arnao J, Yarwood G, Ferguson C et al. (1996). Reduction in circulating IGF-I and hepatic IGF-I mRNA levels after caecal ligation and puncture are associated with differential regulation of hepatic IGF-binding protein-1, -2 and -3 mRNA levels. nameOfConference DOI: 10.1677/joe.0.1510287 QMRO: qmroHref Timmins ACF, Cotterill AMM, Hughes SCPC et al. (1996). Critical illness is associated with low circulating concentrations of insulin-like growth factors-I and -II, alterations in insulin-like growth factor binding proteins, and induction of an insulin-like growth factor binding protein 3 protease. nameOfConference DOI: 10.1097/00003246-199609000-00006 QMRO: qmroHref Hinds C, Watson D (1995). Manipulating Hemodynamics and Oxygen Transport in Critically Ill Patients. nameOfConference DOI: 10.1056/nejm199510193331609 QMRO: qmroHref Hayes M, Timmins A, Yau E et al. (1995). Elevation of systemic oxygen delivery in the treatment of critically ill patients New Engl J Med 1994; 330/24: 1717–1722. nameOfConference DOI: 10.1016/0300-9572(95)90694-d QMRO: qmroHref HAYES MA, TIMMINS AC, YAU EHS et al. (1995). Elevation of Systemic Oxygen in the Treatment of Critically Ill Patients. nameOfConference DOI: 10.1097/00132586-199502000-00043 QMRO: qmroHref Pick B, Molloy A, Hinds C et al. (1994). Post-operative fatigue following coronary artery bypass surgery: Relationship to emotional state and to the catecholamine response to surgery. nameOfConference DOI: 10.1016/0022-3999(94)90057-4 QMRO: qmroHref Hayes MA, Timmins AC, Yau E et al. (1994). Elevation of Systemic Oxygen Delivery in the Treatment of Critically Ill Patients. nameOfConference DOI: 10.1056/nejm199406163302404 QMRO: qmroHref TlMMINS AC, GILES M, NATHAN AW et al. (1994). Clinical validation of a radionuclide detector to measure ejection fraction in critically ill patients. nameOfConference DOI: 10.1093/bja/72.5.523 QMRO: qmroHref Hinds CJ, Yarwood GD, Coakley JH (1994). Acquired Neuromuscular Abnormalities in Intensive Care Patients. nameOfConference DOI: 10.1007/978-3-642-85068-4_62 QMRO: qmroHref HAYES MA, PALAZZO M, HINDS CJ et al. (1994). ELEVATION OF SYSTEMIC OXYGEN DELIVERY IN THE TREATMENT OF CRITICALLY ILL PATIENTS - REPLY. nameOfConference DOI: doi QMRO: qmroHref Hinds CJ, Nagendran K, Honauar M et al. (1993). Muscle Relaxants in Intensive Care Patients. nameOfConference DOI: 10.1097/00003246-199309000-00029 QMRO: qmroHref Hinds CJ, Watson JD, Hayes M et al. (1993). High dose inotropic support in septic shock.. nameOfConference DOI: 10.1136/bmj.307.6901.446-a QMRO: qmroHref Palazzo M, Soni N, Hinds C (1993). Physiological scoring systems and audit.. nameOfConference DOI: doi QMRO: qmroHref Rothwell PM, Chang RS, Bihari D et al. (1993). Physiological scoring systems and audit. nameOfConference DOI: 10.1016/0140-6736(93)91854-f QMRO: qmroHref Coakley JH, Nagendran K, Honavar M et al. (1993). Preliminary observations on the neuromuscular abnormalities in patients with organ failure and sepsis. nameOfConference DOI: 10.1007/bf01694705 QMRO: qmroHref Donaldson MD, Vesey CJ, Bouloux PM et al. (1993). Plasma catecholamine levels in porcine Escherichia coli septicaemia and following treatment with buprenorphine or naloxone.. nameOfConference DOI: doi QMRO: qmroHref Hayes MA, Yau EHS, Timmins AC et al. (1993). Response of Critically III Patients to Treatment Aimed at Achieving Supranormal Oxygen Delivery and Consumption Relationship to Outcome. nameOfConference DOI: 10.1378/chest.103.3.886 QMRO: qmroHref CATNACH SM, HINDS CJ, FAIRCLOUGH PD (1993). ENTERAL NUTRITION DOES NOT PROTECT AGAINST BILIARY SLUDGE IN CRITICALLY ILL PATIENTS. nameOfConference DOI: doi QMRO: qmroHref Cwyfan Hughes SC, Cotterill AM, Molloy AR et al. (1992). The induction of specific proteases for insulin-like growth factor-binding proteins following major heart surgery. nameOfConference DOI: 10.1677/joe.0.1350135 QMRO: qmroHref Gore SM, Armitage WJ, Briggs JD et al. (1992). Consensus on general medical contraindications to organ donation?. nameOfConference DOI: 10.1136/bmj.305.6850.406 QMRO: qmroHref Hayes MA, Yau EHS, Hinds CJ et al. (1992). Symmetrical peripheral gangrene: association with noradrenaline administration. nameOfConference DOI: 10.1007/bf01694349 QMRO: qmroHref Coakley JH, Nagendran K, Ormerod IEC et al. (1992). Prolonged Neurogenic Weakness in Patients Requiring Mechanical Ventilation for Acute Airflow Limitation. nameOfConference DOI: 10.1378/chest.101.5.1413 QMRO: qmroHref Hinds CJ (1992). Monoclonal antibodies in sepsis: Author's reply. nameOfConference DOI: 10.1136/bmj.304.6833.1054-b QMRO: qmroHref Hinds CJ (1992). Monoclonal antibodies in sepsis and septic shock.. nameOfConference DOI: 10.1136/bmj.304.6820.132 QMRO: qmroHref Timmins AC, Hayes M, Yau E et al. (1992). The relationship between cardiac reserve and survival in critically ill patients receiving treatment aimed at achieving supranormal oxygen delivery and consumption.. nameOfConference DOI: doi QMRO: qmroHref Donaldson MD, Vesey CJ, Wilks M et al. (1991). Lack of effect of ACTH in porcine Escherichia coli septic shock.. nameOfConference DOI: doi QMRO: qmroHref Yau E, Rohatiner A, Lister T et al. (1991). Long term prognosis and quality of life following intensive care for life-threatening complications of haematological malignancy. nameOfConference DOI: 10.1038/bjc.1991.430 QMRO: qmroHref Timmins AC, Hinds CJ (1991). Availability of cadaver organs for transplantation.. nameOfConference DOI: 10.1136/bmj.303.6802.583-a QMRO: qmroHref Amos RJ, Deane M, Ferguson C et al. (1990). Observations on the haemopoietic response to critical illness.. nameOfConference DOI: 10.1136/jcp.43.10.850 QMRO: qmroHref Gore SM, Holland AJ, Hinds CJ (1990). Organs for transplantation.. nameOfConference DOI: 10.1136/bmj.300.6722.464-e QMRO: qmroHref HINDS CJ, AMESS JAL, JEFFERIES G et al. (1990). ABNORMALITIES OF BONE-MARROW MORPHOLOGY AND FUNCTION IN CRITICALLY ILL PATIENTS. nameOfConference DOI: doi QMRO: qmroHref Hinds CJ, Yau EHS (1990). Intensive Care for Complications of Malignant Disease: Presentation and Outcome. nameOfConference DOI: 10.1007/978-3-642-84125-5_86 QMRO: qmroHref Gore SM, Rutherford AJ, Hinds CJ (1989). Organ donation from intensive care units in England. nameOfConference DOI: 10.1136/bmj.299.6712.1399-a QMRO: qmroHref Gore SM, Hinds CJ, Rutherford AJ (1989). Organ donation from intensive care units in England.. nameOfConference DOI: 10.1136/bmj.299.6709.1193 QMRO: qmroHref Van Besouw JP, Hinds CJ (1989). Fat embolism syndrome.. nameOfConference DOI: doi QMRO: qmroHref McLoughlin L, Evans SF, Watson JD et al. (1988). Characterization of circulating pro-opiomelanocortin-related peptides in human septic shock. nameOfConference DOI: 10.1677/joe.0.1190159 QMRO: qmroHref Watson JD, Varley JG, Bouloux PM et al. (1988). Adrenal vein and arterial levels of catecholamines and immunoreactive metenkephalin in canine endotoxin shock and their response to naloxone. nameOfConference DOI: 10.1007/bf01851200 QMRO: qmroHref Watson JD, Varley JG, Tomlin SJ et al. (1988). Neuroendocrine and cardiovascular responses to high-dose corticosteroid therapy in canine endotoxin shock. nameOfConference DOI: 10.1007/bf01851201 QMRO: qmroHref Donaldson MD, Vesey CJ, Wilks M et al. (1988). Beneficial effects of buprenorphine (a partial opiate agonist) in porcine Escherichia coli septicaemia: a comparison with naloxone.. nameOfConference DOI: doi QMRO: qmroHref Lloyd-Thomas AR, Wright I, Lister TA et al. (1988). Prognosis of patients receiving intensive care for lifethreatening medical complications of haematological malignancy. nameOfConference DOI: 10.1136/bmj.296.6628.1025 QMRO: qmroHref Watson JD, Sury MR, Corder R et al. (1988). Plasma levels of neuropeptide tyrosine Y (NPY) are increased in human sepsis but are unchanged during canine endotoxin shock despite raised catecholamine concentrations. nameOfConference DOI: 10.1677/joe.0.1160421 QMRO: qmroHref Procaccio F, Bingham RM, Hinds CJ et al. (1988). Continuous EEG and ICP monitoring as a guide to the administration of althesin sedation in severe head injury. nameOfConference DOI: 10.1007/bf00257469 QMRO: qmroHref DONALDSON M, VESEY C, WILKS M et al. (1988). BENEFICIAL-EFFECTS OF BUPRENORPHINE (A PARTIAL OPIATE AGONIST) IN PORCINE ESCHERICHIA-COLI SEPTICEMIA - A COMPARISON WITH NALOXONE. nameOfConference DOI: doi QMRO: qmroHref Amos RJ, Kirk B, Amess JAL et al. (1987). Bone Marrow Hypoplasia During Intensive Care: Bone Marrow Culture Studies Implicating Ranitidine in the Suppression of Haemopoiesis. nameOfConference DOI: 10.1177/096032718700600609 QMRO: qmroHref Grebenik CR, Hinds CJ (1987). Management of the multiple organ donor.. nameOfConference DOI: doi QMRO: qmroHref BINGHAM RM, HINDS CJ (1987). INFLUENCE OF BOLUS DOSES OF PHENOPERIDINE ON INTRACRANIAL PRESSURE AND SYSTEMIC ARTERIAL PRESSURE IN TRAUMATIC COMA. nameOfConference DOI: 10.1093/bja/59.5.592 QMRO: qmroHref Watson JD, Varley JG, Tomlin SJ et al. (1986). Biochemical characterization of circulating Met-enkephalins in canine endotoxin shock. nameOfConference DOI: 10.1677/joe.0.1110329 QMRO: qmroHref Lloyd-Thomas AR, Dhaliwal HS, Lister TA et al. (1986). Intensive therapy for life-threatening medical complications of haematological malignancy. nameOfConference DOI: 10.1007/bf00261745 QMRO: qmroHref WATSON JD, CORDER R, CARSON R et al. (1986). LACK OF RELATIONSHIP BETWEEN PLASMA-LEVELS OF CATECHOLAMINES AND NEUROPEPTIDE-Y IMMUNOREACTIVITY DURING ENDOTOXIN-SHOCK. nameOfConference DOI: doi QMRO: qmroHref Amos RJ, Amess JA, Hinds CJ et al. (1985). Investigations into the effect of nitrous oxide anaesthesia on folate metabolism in patients receiving intensive care.. nameOfConference DOI: doi QMRO: qmroHref Hinds CJ (1985). Opiate antagonists in shock.. nameOfConference DOI: doi QMRO: qmroHref Hinds CJ (1985). Prevention and treatment of brain ischaemia.. nameOfConference DOI: 10.1136/bmj.291.6498.758 QMRO: qmroHref BINGHAM RM, PROCACCIO F, PRIOR PF et al. (1985). CEREBRAL ELECTRICAL ACTIVITY INFLUENCES THE EFFECTS OF ETOMIDATE CEREBRAL PERFUSION PRESSURE IN TRAUMATIC COMA. nameOfConference DOI: 10.1093/bja/57.9.843 QMRO: qmroHref McCulloch W, Price P, Hinds CJ et al. (1985). Effects of low dose oral triiodothyronine in myxoedema coma. nameOfConference DOI: 10.1007/bf00260360 QMRO: qmroHref Hinds CJ, Evans SF, Varley JG et al. (1985). Neuroendocrine and cardiovascular changes in septic shock and after cardiac surgery: effect of high-dose corticosteroid therapy.. nameOfConference DOI: doi QMRO: qmroHref Watson JD, Bouloux PM, Hinds CJ (1984). ABC of poisoning: opioids. nameOfConference DOI: 10.1136/bmj.289.6457.1538-a QMRO: qmroHref Glynn C (1984). Etomidate and adrenocortical function. nameOfConference DOI: 10.1007/bf00256268 QMRO: qmroHref THOMAS DJB, HINDS CJ, REES GM (1984). The Management of Insulin Dependent Diabetes During Cardiopulmonary Bypass and General Surgery. nameOfConference DOI: 10.1097/00132586-198408000-00037 QMRO: qmroHref Evans SF, Medbak S, Hinds CJ et al. (1984). Plasma levels and biochemical characterisation of circulating met-enkephalin in canine endotoxin shock. nameOfConference DOI: 10.1016/0024-3205(84)90063-8 QMRO: qmroHref WATSON JD, VARLEY JG, HINDS CJ et al. (1984). ADRENAL VEIN AND SYSTEMIC LEVELS OF CATECHOLAMINES AND METENKEPHALIN-LIKE IMMUNOREACTIVITY IN CANINE ENDOTOXIN-SHOCK - EFFECTS OF NALOXONE ADMINISTRATION. nameOfConference DOI: doi QMRO: qmroHref Hinds CJ, Roberts MJ, Ingram D et al. (1984). Computer simulation to predict patient responses to alterations in the ventilation regime. nameOfConference DOI: 10.1007/bf00258063 QMRO: qmroHref Roberts MJ, Boustred ML, Hinds CJ (1983). A multipatient mass spectrometer based system for the measurement of metabolic gas exchange in artificially ventilated intensive care patients. nameOfConference DOI: 10.1007/bf01692553 QMRO: qmroHref Prior JGL, Hinds CJ, Williams J et al. (1983). The use of etomidate in the management of severe head injury. nameOfConference DOI: 10.1007/bf01692549 QMRO: qmroHref EVANS SF, VARLEY JG, HINDS CJ (1983). EFFECTS OF NALOXONE IN CANINE ENDOTOXIN-SHOCK. nameOfConference DOI: doi QMRO: qmroHref Amos RJ, Hinds CJ, Amess JAL et al. (1982). INCIDENCE AND PATHOGENESIS OF ACUTE MEGALOBLASTIC BONE-MARROW CHANGE IN PATIENTS RECEIVING INTENSIVE CARE. nameOfConference DOI: 10.1016/s0140-6736(82)90808-x QMRO: qmroHref Hinds CJ, Ingram D, Dickinson CJ (1982). Self-instruction and assessment in techniques of intensive care using a computer model of the respiratory system. nameOfConference DOI: 10.1007/bf01693430 QMRO: qmroHref AMESS JA, HINDS CJ, MOLLIN DL (1982). A STUDY OF MEGALOBLASTIC CHANGE DEVELOPING IN PATIENTS RECEIVING INTENSIVE-CARE. nameOfConference DOI: doi QMRO: qmroHref KRAPEZ JR, SALOOJEE Y, HINDS CJ et al. (1980). BLOOD CONCENTRATIONS OF NITROUS OXIDE IN THEATRE PERSONNEL. nameOfConference DOI: 10.1093/bja/52.11.1143 QMRO: qmroHref Hinds CJ, Ingram D, Adams L et al. (1980). An Evaluation of the Clinical Potential of a Comprehensive Model of Human Respiration in Artificially Ventilated Patients. nameOfConference DOI: 10.1042/cs0580083 QMRO: qmroHref COLE AGH, HINDS CJ, COLE PV (1980). FENTANYL BY INFUSION - METHOD OF TOTAL DOSE REDUCTION. nameOfConference DOI: doi QMRO: qmroHref HINDS CJ, INGRAM D, DICKINSON CJ (1980). SELF INSTRUCTION AND ASSESSMENT IN TECHNIQUES OF INTENSIVE-CARE USING A COMPUTER-MODEL OF THE RESPIRATORY SYSTEM. nameOfConference DOI: doi QMRO: qmroHref Ingram D, Hinds CJ, Dickinson CJ (1979). Clinical Applications of a Holistic Model. nameOfConference DOI: 10.1042/cs056029pa QMRO: qmroHref CollaboratorsExternal Professor Julian Knight (Wellcome Trust Centre for Human Genomics, Oxford) Professor Tony Gordon (Imperial College) Dr Emma Davenport (Sanger Institute, Cambridge) Dr Kate Burnham (Sanger Institute, Cambridge) Back to top