Dr Alessandra Nerviani

Publications

• Faust HJ, Cheng T-Y, Korsunsky I et al. (publicationYear). Adipocyte associated glucocorticoid signaling regulates normal fibroblast function which is lost in inflammatory arthritis. nameOfConference

  
  

  DOI: 10.1038/s41467-024-52586-x

  
  

  QMRO: qmroHref
• Thomas BL, Montero‐Melendez T, Oggero S et al. (2024). Molecular Determinants of Neutrophil Extracellular Vesicles That Drive Cartilage Regeneration in Inflammatory Arthritis. nameOfConference

  
  

  DOI: 10.1002/art.42958

  
  

  QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/98715
• Law C, Wacleche VS, Cao Y et al. (2024). Publisher Correction: Interferon subverts an AHR–JUN axis to promote CXCL13+ T cells in lupus. nameOfConference

  
  

  DOI: 10.1038/s41586-024-07845-8

  
  

  QMRO: qmroHref
• Apostolo D, D’Onghia D, Nerviani A et al. (publicationYear). Could Gas6/TAM Axis Provide Valuable Insights into the Pathogenesis of Systemic Sclerosis?. nameOfConference

  
  

  DOI: 10.3390/cimb46070444

  
  

  QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/100450
• Law C, Wacleche VS, Cao Y et al. (2024). Interferon subverts an AHR–JUN axis to promote CXCL13+ T cells in lupus. nameOfConference

  
  

  DOI: 10.1038/s41586-024-07627-2

  
  

  QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/100564
• Dunlap G, Wagner A, Meednu N et al. (publicationYear). Clonal associations between lymphocyte subsets and functional states in rheumatoid arthritis synovium. nameOfConference

  
  

  DOI: 10.1038/s41467-024-49186-0

  
  

  QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/100407
• Weinand K, Sakaue S, Nathan A et al. (publicationYear). The chromatin landscape of pathogenic transcriptional cell states in rheumatoid arthritis. nameOfConference

  
  

  DOI: 10.1038/s41467-024-48620-7

  
  

  QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/100769
• Perera J, Delrosso CA, Nerviani A et al. (publicationYear). Clinical Phenotypes, Serological Biomarkers, and Synovial Features Defining Seropositive and Seronegative Rheumatoid Arthritis: A Literature Review. nameOfConference

  
  

  DOI: 10.3390/cells13090743

  
  

  QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/100404
• Sakaue S, Weinand K, Isaac S et al. (2024). Tissue-specific enhancer–gene maps from multimodal single-cell data identify causal disease alleles. nameOfConference

  
  

  DOI: 10.1038/s41588-024-01682-1

  
  

  QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/100780
• Nerviani A, Boutet M-A, Ghirardi GM et al. (publicationYear). Axl and MerTK regulate synovial inflammation and are modulated by IL-6 inhibition in rheumatoid arthritis. nameOfConference

  
  

  DOI: 10.1038/s41467-024-46564-6

  
  

  QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/95783
• Pontarini E, Sciacca E, Chowdhury F et al. (2024). Serum and Tissue Biomarkers Associated With Composite of Relevant Endpoints for Sjögren Syndrome (CRESS) and Sjögren Tool for Assessing Response (STAR) to B Cell–Targeted Therapy in the Trial of Anti–B Cell Therapy in Patients With Primary Sjögren Syndrome (TRACTISS). nameOfConference

  
  

  DOI: 10.1002/art.42772

  
  

  QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/93514
• Weisenfeld D, Zhang F, Donlin L et al. (2024). Associations Between Rheumatoid Arthritis Clinical Factors and Synovial Cell Types and States. nameOfConference

  
  

  DOI: 10.1002/art.42726

  
  

  QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/100592
• Ghirardi GM, Delrosso CA, Nerviani A et al. (2024). Molecular portrait of chronic joint diseases: Defining endotypes toward personalized medicine. nameOfConference

  
  

  DOI: 10.1016/j.jbspin.2024.105692

  
  

  QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/95784
• Kang JB, Shen AZ, Gurajala S et al. (2023). Mapping the dynamic genetic regulatory architecture of HLA genes at single-cell resolution. nameOfConference

  
  

  DOI: 10.1038/s41588-023-01586-6

  
  

  QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/93617
• Boutet M-A, Nerviani A, Fossati-Jimack L et al. (2024). Comparative analysis of late-stage rheumatoid arthritis and osteoarthritis reveals shared histopathological features. nameOfConference

  
  

  DOI: 10.1016/j.joca.2023.10.009

  
  

  QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/92600
• Zhang F, Jonsson AH, Nathan A et al. (2023). Deconstruction of rheumatoid arthritis synovium defines inflammatory subtypes. nameOfConference

  
  

  DOI: 10.1038/s41586-023-06708-y

  
  

  QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/92601
• Rivellese F, Nerviani A, Giorli G et al. (2023). Stratification of biological therapies by pathobiology in biologic-naive patients with rheumatoid arthritis (STRAP and STRAP-EU): two parallel, open-label, biopsy-driven, randomised trials. nameOfConference

  
  

  DOI: 10.1016/s2665-9913(23)00241-2

  
  

  QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/91982
• Ghirardi GM, Nerviani A, Fossati-Jimack L et al. (2023). AB0067 MODE OF ACTION AND TARGET INVESTIGATION OF THE NEW ANTI-RHEUMATIC DRUG RABEXIMOD.. nameOfConference

  
  

  DOI: 10.1136/annrheumdis-2023-eular.5727

  
  

  QMRO: qmroHref
• Rivellese F, Currado D, Giorli G et al. (2023). AB0340 MULTI-DRUG RESISTANT RA IS ASSOCIATED WITH HIGHER BASELINE DISEASE ACTIVITY, MULTI-MORBIDITY, AND LOWER QUALITY OF LIFE: ANALYSES FROM THE R4RA BIOPSY-DRIVEN CLINICAL TRIAL. nameOfConference

  
  

  DOI: 10.1136/annrheumdis-2023-eular.750

  
  

  QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/92604
• Sobrado M, Nerviani A, Eldaw T et al. (2023). P020 Audit of bosentan use in Rapid Access to Digital Ulcer Clinic (RADUC) in systemic sclerosis: a single-centre experience. nameOfConference

  
  

  DOI: 10.1093/rheumatology/kead104.062

  
  

  QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/92151
• Wang J, Conlon D, Rivellese F et al. (2022). Synovial Inflammatory Pathways Characterize Anti‐TNF–Responsive Rheumatoid Arthritis Patients. nameOfConference

  
  

  DOI: 10.1002/art.42295

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/80119
• Rivellese F, Cubuk C, Surace A et al. (2022). OP0085 CELL LINEAGE-SPECIFIC TRANSCRIPT DECONVOLUTION OF SYNOVIAL BIOPSIES FROM THE R4RA TRIAL IDENTIFIES CELL POPULATIONS ASSOCIATED WITH RESPONSE TO RITUXIMAB AND TOCILIZUMAB. nameOfConference

  
  

  DOI: 10.1136/annrheumdis-2022-eular.4794

  
  

  QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/89103
• Prediletto E, Cubuk C, Pontarini E et al. (2022). POS0138 RHEUMATOID SYNOVIAL FIBROBLASTS DISPLAY IMPRINTED MEMORY OF THEIR SYNOVIAL ENDOTYPE WHICH CAN BE PLASTICALLY MODULATED BY B-CELLS CROSSTALK. nameOfConference

  
  

  DOI: 10.1136/annrheumdis-2022-eular.2758

  
  

  QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/92599
• Pontarini E, Chowdhury F, Sciacca E et al. (2022). POS0145 CLINICAL RESPONSE TO RITUXIMAB IS ASSOCIATED WITH PREVENTION OF B-CELL DRIVEN SALIVARY GLAND INFLAMMATION AND EPITHELIAL RESTORATION AS REVEALED BY MOLECULAR PATHOLOGY: RESULTS FROM THE TRACTISS TRIAL IN PRIMARY SJOGREN’S SYNDROME. nameOfConference

  
  

  DOI: 10.1136/annrheumdis-2022-eular.4458

  
  

  QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/92607
• Nerviani A, Boutet MA, Ghirardi GM et al. (2022). POS0441 IN-DEPTH ANALYSIS OF Axl AND MerTK EXPRESSION PATTERNS AND REGULATION BY BIOLOGIC TREATMENTS IN RHEUMATOID ARTHRITIS. nameOfConference

  
  

  DOI: 10.1136/annrheumdis-2022-eular.4486

  
  

  QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/79779
• Rivellese F, Surace AEA, Goldmann K et al. (2022). Rituximab versus tocilizumab in rheumatoid arthritis: synovial biopsy-based biomarker analysis of the phase 4 R4RA randomized trial. nameOfConference

  
  

  DOI: 10.1038/s41591-022-01789-0

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/78741
• Carlucci PM, Li J, Fava A et al. (2022). High incidence of proliferative and membranous nephritis in SLE patients with low proteinuria in the Accelerating Medicines Partnership. nameOfConference

  
  

  DOI: 10.1093/rheumatology/keac067

  
  

  QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/77492
• Rivellese F, Pontarini E, Cubuk C et al. (2022). Module Signatures of Synovial Single-cell States Identify Disease Phenotypes in Early Treatment-naive Rheumatoid Arthritis. nameOfConference

  
  

  DOI: doi

  
  

  QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/88925
• Prediletto E, Cubuk C, Pontarini E et al. (2022). Rheumatoid Synovial Fibroblasts Display Imprinted Memory of Their Synovial Endotype Which Can Be Plastically Modulated by B-cells Crosstalk. nameOfConference

  
  

  DOI: doi

  
  

  QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/83754
• Deonaraine KK, Carlucci PM, Fava A et al. (2021). Safety of procuring research tissue during a clinically indicated kidney biopsy from patients with lupus: data from the Accelerating Medicines Partnership RA/SLE Network. nameOfConference

  
  

  DOI: 10.1136/lupus-2021-000522

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/77495
• Boutet M-A, Nerviani A, Lliso-Ribera G et al. (publicationYear). Circulating and Synovial Pentraxin-3 (PTX3) Expression Levels Correlate With Rheumatoid Arthritis Severity and Tissue Infiltration Independently of Conventional Treatments Response. nameOfConference

  
  

  DOI: 10.3389/fimmu.2021.686795

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/77488
• Rivellese F, Pontarini E, Fossati-Jimack L et al. (2021). OP0011 INTEGRATION OF FLOW AND DIGITAL CYTOMETRY IN EARLY TREATMENT-NAÏVE RHEUMATOID ARTHRITIS IDENTIFIES DISTINCT IMMUNOPHENOTYPES IN PERIPHERAL BLOOD AND DISEASE TISSUE. nameOfConference

  
  

  DOI: 10.1136/annrheumdis-2021-eular.438

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/77498
• Fanelli G, Romano M, Nova-Lamperti E et al. (publicationYear). PD-L1 signaling on human memory CD4+ T cells induces a regulatory phenotype. nameOfConference

  
  

  DOI: 10.1371/journal.pbio.3001199

  
  

  QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/92470
• Ferrari M, Onuoha SC, Fossati-Jimack L et al. (2021). Novel Bispecific Antibody for Synovial-Specific Target Delivery of Anti-TNF Therapy in Rheumatoid Arthritis. nameOfConference

  
  

  DOI: 10.3389/fimmu.2021.640070

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/71217
• Pitzalis C, Humby F, Rivellese F et al. (2021). Rituximab versus Tocilizumab in anti-TNF inadequate responder patients with Rheumatoid Arthritis (R4RA): a stratified, biopsy-driven, multi-centre, randomised, open label, controlled clinical trial – 16 week outcomes Article (Randomised Controlled Trial). nameOfConference

  
  

  DOI: doi

  
  

  QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/69717
• Boutet M-A, Courties G, Nerviani A et al. (2021). Novel insights into macrophage diversity in rheumatoid arthritis synovium. nameOfConference

  
  

  DOI: 10.1016/j.autrev.2021.102758

  
  

  QMRO: qmroHref
• Sainaghi PP, Bellan M, Nerviani A (2021). Role of the Gas6/TAM System as a Disease Marker and Potential Drug Target. nameOfConference

  
  

  DOI: 10.1155/2021/2854925

  
  

  QMRO: qmroHref
• Boutet MA, Nerviani A, Ribera GL et al. (2021). Pentraxin-3 (PTX3) circulating and synovial expression levels correlate with rheumatoid arthritis severity and tissue infiltration independently of the response to conventional treatments. nameOfConference

  
  

  DOI: doi

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/77496
• Humby F, Durez P, Buch MH et al. (2021). Rituximab versus tocilizumab in anti-TNF inadequate responder patients with rheumatoid arthritis (R4RA): 16-week outcomes of a stratified, biopsy-driven, multicentre, open-label, phase 4 randomised controlled trial. nameOfConference

  
  

  DOI: 10.1016/s0140-6736(20)32341-2

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/70235
• Nerviani A, Boutet M-A, Tan WSG et al. (2020). IL-23 skin and joint profiling in Psoriatic Arthritis: novel perspectives in understanding clinical responses to IL-23 inhibitors. nameOfConference

  
  

  DOI: 10.1136/annrheumdis-2020-218186

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/68358
• Alivernini S, MacDonald L, Elmesmari A et al. (2020). Distinct synovial tissue macrophage subsets regulate inflammation and remission in rheumatoid arthritis. nameOfConference

  
  

  DOI: 10.1038/s41591-020-0939-8

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/66500
• Bellan M, Quaglia M, Nerviani A et al. (2021). Increased plasma levels of Gas6 and its soluble tyrosine kinase receptors Mer and Axl are associated with immunological activity and severity of lupus nephritis.. nameOfConference

  
  

  DOI: 10.55563/clinexprheumatol/xyylza

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/68045
• Rivellese F, Humby F, Lliso Ribera G et al. (2020). OP0217 INVOLVEMENT OF LARGE JOINTS AT DISEASE PRESENTATION IS ASSOCIATED WITH DIVERSE HISTOPATHOLOGICAL FEATURES AND CLINICAL OUTCOMES IN EARLY RHEUMATOID ARTHRITIS. nameOfConference

  
  

  DOI: 10.1136/annrheumdis-2020-eular.2475

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/71058
• Nerviani A, Boutet MA, Ghirardi GM et al. (2020). THU0082 MERTK SYNOVIAL EXPRESSION CORRELATES WITH TREATMENT RESPONSE IN RHEUMATOID ARTHRITIS. nameOfConference

  
  

  DOI: 10.1136/annrheumdis-2020-eular.4207

  
  

  QMRO: qmroHref
• Bellan M, Dimagli A, Piccinino C et al. (2020). Role of Gas6 and TAM Receptors in the Identification of Cardiopulmonary Involvement in Systemic Sclerosis and Scleroderma Spectrum Disorders. nameOfConference

  
  

  DOI: 10.1155/2020/2696173

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/68521
• Nerviani A, Di Cicco M, Mahto A et al. (publicationYear). A Pauci-Immune Synovial Pathotype Predicts Inadequate Response to TNFα-Blockade in Rheumatoid Arthritis Patients. nameOfConference

  
  

  DOI: 10.3389/fimmu.2020.00845

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/65198
• Humby FC, Lewis M, Durez P et al. (2020). O07 Randomised, open labelled clinical trial to investigate synovial mechanisms determining response: resistance to rituximab versus tocilizumab in RA patients failing TNF inhibitor therapy. nameOfConference

  
  

  DOI: 10.1093/rheumatology/keaa110.006

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/68070
• Nerviani A, Lliso-Ribera G, Boutet M-A et al. (2020). O20 Histological and molecular features of the diseased synovium in early untreated PsA in comparison with RA. nameOfConference

  
  

  DOI: 10.1093/rheumatology/keaa110.019

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/68071
• Rivellese F, Humby F, Bugatti S et al. (2020). P233 B cell-rich synovitis in early and established rheumatoid arthritis. nameOfConference

  
  

  DOI: 10.1093/rheumatology/keaa111.227

  
  

  QMRO: qmroHref
• Rivellese F, Humby F, Bugatti S et al. (publicationYear). B cell synovitis and clinical phenotypes in rheumatoid arthritis: relationship to disease stages and drug exposure.. nameOfConference

  
  

  DOI: 10.1002/art.41184

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/63258
• Pagani S, Bellan M, Mauro D et al. (2020). New Insights into the Role of Tyro3, Axl, and Mer Receptors in Rheumatoid Arthritis. nameOfConference

  
  

  DOI: 10.1155/2020/1614627

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/62984
• Rivellese F, Humby F, Bugatti S et al. (2020). B CELL-RICH SYNOVITIS IN EARLY AND ESTABLISHED RHEUMATOID ARTHRITIS. nameOfConference

  
  

  DOI: doi

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/68913
• Nerviani A, Lliso-Ribera G, Boutet M-A et al. (2020). HISTOLOGICAL AND MOLECULAR FEATURES OF THE DISEASED SYNOVIUM IN EARLY UNTREATED PSA IN COMPARISON WITH RA. nameOfConference

  
  

  DOI: doi

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/65697
• Rivellese F, Humby F, Giorli G et al. (2020). Histo-pathological Cellular Markers of Treatment Response to Rituximab and Tocilizumab in Matched Pre- and Post-treatment Synovial Biopsies from the R4RA Randomised Clinical Trial in Rheumatoid Arthritis. nameOfConference

  
  

  DOI: doi

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/70852
• Nerviani A, Boutet M-A, Ghirardi GM et al. (2020). MerTK Synovial Expression Correlates with Disease Activity and Treatment Response in Rheumatoid Arthritis Patients. nameOfConference

  
  

  DOI: doi

  
  

  QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/70851
• Humby FC, Lewis M, Durez P et al. (2020). RANDOMISED, OPEN LABELLED CLINICAL TRIAL TO INVESTIGATE SYNOVIAL MECHANISMS DETERMINING RESPONSE: RESISTANCE TO RITUXIMAB VERSUS TOCILIZUMAB IN RA PATIENTS FAILING TNF INHIBITOR THERAPY. nameOfConference

  
  

  DOI: doi

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/66599
• Bellan M, Patrucco F, Barone-Adesi F et al. (2020). Targeting CD20 in the treatment of interstitial lung diseases related to connective tissue diseases: A systematic review. nameOfConference

  
  

  DOI: 10.1016/j.autrev.2019.102453

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/68241
• Lliso-Ribera G, Humby F, Lewis M et al. (2019). Synovial tissue signatures enhance clinical classification and prognostic/treatment response algorithms in early inflammatory arthritis and predict requirement for subsequent biological therapy: results from the pathobiology of early arthritis cohort (PEAC). nameOfConference

  
  

  DOI: 10.1136/annrheumdis-2019-215751

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/63523
• Bellan M, Andreoli L, Nerviani A et al. (2020). Is cholecalciferol a potential disease-modifying anti-rheumatic drug for the management of rheumatoid arthritis?. nameOfConference

  
  

  DOI: 10.55563/clinexprheumatol/tdf172

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/68561
• Boutet M-A, Nerviani A, Lliso-Ribera G et al. (2019). Interleukin-36 family dysregulation drives joint inflammation and therapy response in psoriatic arthritis.. nameOfConference

  
  

  DOI: 10.1093/rheumatology/kez358

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/62220
• Rodríguez-Ubreva J, de la Calle-Fabregat C, Li T et al. (2019). Inflammatory cytokines shape a changing DNA methylome in monocytes mirroring disease activity in rheumatoid arthritis. nameOfConference

  
  

  DOI: 10.1136/annrheumdis-2019-215355

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/69712
• El Shikh MEM, El Sayed R, Nerviani A et al. (2019). Extracellular traps and PAD4 released by macrophages induce citrullination and auto-antibody production in autoimmune arthritis. nameOfConference

  
  

  DOI: 10.1016/j.jaut.2019.06.008

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/58983
• Mattiola I, Tomay F, De Pizzol M et al. (2019). The macrophage tetraspan MS4A4A enhances dectin-1-dependent NK cell–mediated resistance to metastasis. nameOfConference

  
  

  DOI: 10.1038/s41590-019-0417-y

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/58603
• Rivellese F, Humby F, Bugatti S et al. (2019). THU0058 B CELL SYNOVITIS AND CLINICAL PHENOTYPES IN RHEUMATOID ARTHRITIS AT DIFFERENT DISEASE STAGES. Annual European Congress of Rheumatology, EULAR 2019

  
  

  DOI: 10.1136/annrheumdis-2019-eular.1284

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/68914
• Nerviani A, Ribera GL, Boutet MA et al. (2019). OP0113 HISTOLOGICAL AND MOLECULAR PORTRAIT OF THE SYNOVIAL TISSUE IN EARLY TREATMENT-NAÏVE PSORIATIC ARTHRITIS IN COMPARISON WITH RHEUMATOID ARTHRITIS. Oral Presentations

  
  

  DOI: 10.1136/annrheumdis-2019-eular.3634

  
  

  QMRO: qmroHref
• Ribera GL, Humby F, Nerviani A et al. (2019). OP0120 BASELINE CELLULAR AND MOLECULAR CHARACTERISTICS OF SYNOVIAL TISSUE AND RELATION WITH TNFI RESPONSE. RESULTS FROM THE PATHOBIOLOGY OF THE EARLY ARTHRITIS COHORT (PEAC). Oral Presentations

  
  

  DOI: 10.1136/annrheumdis-2019-eular.2617

  
  

  QMRO: qmroHref
• Nerviani A, Humby F, Ribera GL et al. (2019). THU0092 DEFINING A LEARNING CURVE FOR CLINICIANS PERFORMING ULTRASOUND-GUIDED DEFINING A LEARNING CURVE FOR CLINICIANS PERFORMING ULTRASOUND-GUIDED NEEDLE SYNOVIAL BIOPSIES: A RETROSPECTIVE ANALYSIS OF THE EXPERIENCE AT THE EXPERIMENTAL MEDICINE AND RHEUMATOLOGY, QUEEN MARY UNIVERSITY OF LONDON. Poster Presentations

  
  

  DOI: 10.1136/annrheumdis-2019-eular.7302

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/65543
• Boutet M-A, Nerviani A, Pitzalis C (publicationYear). IL-36, IL-37, and IL-38 Cytokines in Skin and Joint Inflammation: A Comprehensive Review of Their Therapeutic Potential. nameOfConference

  
  

  DOI: 10.3390/ijms20061257

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/58681
• Boutet M-A, Nerviani A, Lliso-Ribera G et al. (2019). P125 IL-36 axis is an emerging therapeutic target in psoriatic arthritis synovial tissue. Abstracts

  
  

  DOI: 10.1136/annrheumdis-2018-ewrr2019.113

  
  

  QMRO: qmroHref
• Rivellese F, Lliso-Ribera G, Nerviani A et al. (2019). Persistence of B Cell-rich Synovitis Following Conventional Synthetic Disease Modifying Anti-Rheumatic Drug Treatment in Early Rheumatoid Arthritis Is Associated with Radiographic Progression Independently of Clinical Response. nameOfConference

  
  

  DOI: doi

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/66635
• Mauro D, Macaluso F, Nerviani A et al. (2019). The Deubiquitinase TRABID Is a Potential Therapeutic Target in Spondyloarthritis. nameOfConference

  
  

  DOI: doi

  
  

  QMRO: qmroHref
• Mattiola I, Tomay F, De Pizzol M et al. (2019). The macrophage tetraspan MS4A4A enhances Dectin-1-dependent NK cell-mediated resistance to metastasis. nameOfConference

  
  

  DOI: doi

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/67407
• Bellan M, Nerviani A, Sainaghi PP (2018). The Enigma of Vitamin D Role in Inflammation. nameOfConference

  
  

  DOI: 10.2174/1874312901812010197

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/67406
• Nerviani A, Mauro D, Gilio M et al. (2018). To supplement or not to supplement? The rationale of vitamin D supplementation in systemic lupus erythematosus. nameOfConference

  
  

  DOI: 10.2174/1874312901812010226

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/57680
• Cecchinato V, D'Agostino G, Raeli L et al. (2018). Redox-Mediated Mechanisms Fuel Monocyte Responses to CXCL12/HMGB1 in Active Rheumatoid Arthritis.. nameOfConference

  
  

  DOI: 10.3389/fimmu.2018.02118

  
  

  QMRO: qmroHref
• Rivellese F, Mauro D, Nerviani A et al. (2018). Mast cells in early rheumatoid arthritis associate with disease severity and support B cell autoantibody production. nameOfConference

  
  

  DOI: 10.1136/annrheumdis-2018-213418

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/44263
• Mauro D, Nerviani A (2018). Endothelial Dysfunction in Systemic Lupus Erythematosus: Pathogenesis, Assessment and Therapeutic Opportunities.. nameOfConference

  
  

  DOI: 10.2174/1574887113666180314091831

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/42643
• Nerviani A, Pitzalis C (2018). Role of chemokines in ectopic lymphoid structures formation in autoimmunity and cancer. nameOfConference

  
  

  DOI: 10.1002/jlb.3mr0218-062r

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/42083
• Mauro D, Tsang V, Lucey-Clayton I et al. (2018). FRI0271 Dimethyl fumarate inhibits ube2l3 mediated tlr7 signalling and autoreactive b cell development in sle. FRIDAY, 15 JUNE 2018

  
  

  DOI: 10.1136/annrheumdis-2018-eular.6960

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/66741
• Lliso-Ribera G, Humby F, Nerviani A et al. (2018). OP0040 Synovial cell infiltration in acpa-ve patients displays similar signatures to other seronegative inflammatory arthritis. results from the pathobiology of early arthritis cohort (PEAC). WEDNESDAY, 13 JUNE 2018

  
  

  DOI: 10.1136/annrheumdis-2018-eular.3489

  
  

  QMRO: qmroHref
• Boutet M-A, Nerviani A, Lliso-Ribera G et al. (2018). SAT0024 Il-36 axis is an emerging therapeutic target in psoriatic arthritis synovial tissue. Saturday, 16 JUNE 2018

  
  

  DOI: 10.1136/annrheumdis-2018-eular.3485

  
  

  QMRO: qmroHref
• Rivellese F, Nerviani A, Mauro D et al. (2018). SAT0076 Synovial mast cells and responses to synthetic and biologic dmards in early and established rheumatoid arthritis. Saturday, 16 JUNE 2018

  
  

  DOI: 10.1136/annrheumdis-2018-eular.6839

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/65949
• Nerviani A, Mauro D, Pagani S et al. (2018). THU0061 Restricted axl synovial expression and increased cleavage of axl ectodomain correlate with highly inflamed synovitis and more severe rheumatoid arthritis. THURSDAY, 14 JUNE 2018

  
  

  DOI: 10.1136/annrheumdis-2018-eular.6988

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/65908
• Purkayastha N, Tan WS, Mahto A et al. (2018). THU0122 Imaging characterisation of remission in rheumatoid arthritis. THURSDAY, 14 JUNE 2018

  
  

  DOI: 10.1136/annrheumdis-2018-eular.1264

  
  

  QMRO: qmroHref
• Ribera GL, Humby F, Kelly S et al. (2018). 244 The clinical phenotype of inflammatory arthritis correlates with synovial immune cell infiltration: results from the pathobiology of early arthritis cohort. nameOfConference

  
  

  DOI: 10.1093/rheumatology/key075.468

  
  

  QMRO: qmroHref
• Ribera GL, Humby F, Kelly S et al. (2018). O09 A lymphoid pathotype at baseline, in early inflammatory arthritis, significantly associates with requirement for biologic therapy at 12 months follow up: results from the pathobiology of early arthritis cohort. nameOfConference

  
  

  DOI: 10.1093/rheumatology/key075.191

  
  

  QMRO: qmroHref
• Boutet M-A, Nerviani A, Afflitto GG et al. (publicationYear). Role of the IL-23/IL-17 Axis in Psoriasis and Psoriatic Arthritis: The Clinical Importance of Its Divergence in Skin and Joints. nameOfConference

  
  

  DOI: 10.3390/ijms19020530

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/57967
• Ribera GL, Humby F, Kelly S et al. (2018). A LYMPHOID PATHOTYPE AT BASELINE, IN EARLY INFLAMMATORY ARTHRITIS, SIGNIFICANTLY ASSOCIATES WITH REQUIREMENT FOR BIOLOGIC THERAPY AT 12 MONTHS FOLLOW UP: RESULTS FROM THE PATHOBIOLOGY OF EARLY ARTHRITIS COHORT. nameOfConference

  
  

  DOI: doi

  
  

  QMRO: qmroHref
• Nerviani A, Humby F, Ribera GL et al. (2018). Comparative Histologic and Molecular Analysis of Synovial Tissue in Early Treatment-Naive Psoriatic and Rheumatoid Arthritis. nameOfConference

  
  

  DOI: doi

  
  

  QMRO: qmroHref
• Ribera GL, Humby F, Kelly S et al. (2018). THE CLINICAL PHENOTYPE OF INFLAMMATORY ARTHRITIS CORRELATES WITH SYNOVIAL IMMUNE CELL INFILTRATION: RESULTS FROM THE PATHOBIOLOGY OF EARLY ARTHRITIS COHORT. nameOfConference

  
  

  DOI: doi

  
  

  QMRO: qmroHref
• NERVIANI A (2017). TAM receptors in rheumatoid arthritis: focus on synovial expression, relationship with synovial histopathology and association with clinical evolution and response to treatment. nameOfConference

  
  

  DOI: doi

  
  

  QMRO: qmroHref
• Rivellese F, Humby F, Nerviani A et al. (2017). FRI0030 Synovial mast cells identify patients with a severe phenotype in a cohort of dmard naÏve patients with early rheumatoid arthritis. Poster Presentations

  
  

  DOI: 10.1136/annrheumdis-2017-eular.6393

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/66166
• Lliso-Ribera G, Humby F, Kelly S et al. (2017). FRI0088 Synovial pathobiology correlates with diagnostic subgroups in early inflammatory arthritis: results from the pathobiology of early arthritis cohort (PEAC). Poster Presentations

  
  

  DOI: 10.1136/annrheumdis-2017-eular.2927

  
  

  QMRO: qmroHref
• Lliso-Ribera G, Humby F, Kelly S et al. (2017). THU0100 In early inflammatory arthritis a lymphoid pathotype signficantly associates with requirement for biologic therapy at 12 months follow up: results from the pathobiology of early arthritis cohort (PEAC). Poster Presentations

  
  

  DOI: 10.1136/annrheumdis-2017-eular.6042

  
  

  QMRO: qmroHref
• Rivellese F, Nerviani A, Rossi FW et al. (2017). Mast cells in rheumatoid arthritis: friends or foes?. nameOfConference

  
  

  DOI: 10.1016/j.autrev.2017.04.001

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/50024
• Rivellese F, Humby F, Pagani S et al. (2017). Persistence of Mast Cell-Rich Synovitis Is Associated with Lack of Response to Synthetic Disease Modifying Anti-Rheumatic Drugs in Patients with Early Rheumatoid Arthritis. nameOfConference

  
  

  DOI: doi

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/68782
• Mauro D, Tsang V, Clayton-Lucey IA et al. (2017). Regulation of TLR7 Signalling By UBE2L3 Dependent Linear Ubiquitination Explains Dimethyl Fumarate Suppression of Autoreactive B Cell Development in SLE. nameOfConference

  
  

  DOI: doi

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/65899
• Nerviani A, Pagani S, Mauro D et al. (2017). Tyrosine Kinase Receptor Axl Is Down Regulated in Highly Inflamed Rheumatoid Synovium and Negatively Correlates with Markers of Disease Activity. nameOfConference

  
  

  DOI: doi

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/66227
• Corsiero E, Nerviani A, Bombardieri M et al. (2016). Ectopic Lymphoid Structures: Powerhouse of Autoimmunity.. nameOfConference

  
  

  DOI: 10.3389/fimmu.2016.00430

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/31464
• Nerviani A, DiCicco M, Humby F et al. (2016). FRI0157 A Baseline Prediction Model for Response To Certolizumab-Pegol: Role of Synovial Histopathology. nameOfConference

  
  

  DOI: 10.1136/annrheumdis-2016-eular.4218

  
  

  QMRO: qmroHref
• Nerviani A, Tan WS, Mahto A et al. (2016). FRI0442 Histopathology of Treatment-Naïve Psoriatic Synovitis: A Comparison with Early Rheumatoid Arthritis. nameOfConference

  
  

  DOI: 10.1136/annrheumdis-2016-eular.5321

  
  

  QMRO: qmroHref
• Rivellese F, Humby F, Kelly S et al. (2016). SYNOVIAL MAST CELLS CORRELATE WITH LOCAL AND SYSTEMIC INFLAMMATION AND ARE FUNCTIONALLY ASSOCIATED WITH ECTOPIC LYMPHOID STRUCTURES IN PATIENTS WITH EARLY RHEUMATOID ARTHRITIS. EULAR 2016

  
  

  DOI: doi

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/51563
• Nerviani A, DiCicco M, Kelly S et al. (2016). FIBROID SYNOVIAL PATHOTYPE AND TYROSINE KINASE AXL CORRELATE WITH POOR CLINICAL RESPONSE TO CERTOLIZUMAB PEGOL IN RHEUMATOID ARTHRITIS PATIENTS. Rheumatology 2016

  
  

  DOI: 10.1093/rheumatology/kew121.004

  
  

  QMRO: qmroHref
• Lepse N, Nerviani A, Pitzalis C et al. (2016). 069 T Follicular Helper–Like Cells in the Rheumatoid Arthritis Synovium are Selectively Associated with Interleukin-21 Production and Ectopic Lymphoid Structures. nameOfConference

  
  

  DOI: 10.1093/rheumatology/kew143

  
  

  QMRO: qmroHref
• Sorice M, Iannuccelli C, Manganelli V et al. (publicationYear). Autophagy generates citrullinated peptides in human synoviocytes: a possible trigger for anti-citrullinated peptide antibodies. nameOfConference

  
  

  DOI: 10.1093/rheumatology/kew178

  
  

  QMRO: qmroHref
• Lepse N, Nerviani A, Pitzalis C et al. (2016). A2.30 TFH-like cells in the ra synovium are selectively associated with IL-21 production and ectopic lymphoid structures. nameOfConference

  
  

  DOI: 10.1136/annrheumdis-2016-209124.65

  
  

  QMRO: qmroHref
• Jones GW, Bombardieri M, Greenhill CJ et al. (2016). Interleukin-27 inhibits synovial lymphoid neogenesis in inflammatory arthritis. nameOfConference

  
  

  DOI: doi

  
  

  QMRO: qmroHref
• Lepse N, Nerviani A, Pitzalis C et al. (2016). T FOLLICULAR HELPER-LIKE CELLS IN THE RHEUMATOID ARTHRITIS SYNOVIUM ARE SELECTIVELY ASSOCIATED WITH INTERLEUKIN-21 PRODUCTION AND ECTOPIC LYMPHOID STRUCTURES. nameOfConference

  
  

  DOI: doi

  
  

  QMRO: qmroHref
• Headland SE, Jones HR, Norling LV et al. (2015). Neutrophil-derived microvesicles enter cartilage and protect the joint in inflammatory arthritis. nameOfConference

  
  

  DOI: 10.1126/scitranslmed.aac5608

  
  

  QMRO: qmroHref
• Jones GW, Bombardieri M, Greenhill CJ et al. (2015). Interleukin-27 inhibits ectopic lymphoid-like structure development in early inflammatory arthritis. nameOfConference

  
  

  DOI: 10.1084/jem.20132307

  
  

  QMRO: qmroHref
• Decourcey J, Nerviani A, Melgar S et al. (2015). OP0117 Snare Regulation of TH17 Cells and Ectopic Lymphoid Structure (ELS) Formation in Rheumatoid Arthritis. nameOfConference

  
  

  DOI: 10.1136/annrheumdis-2015-eular.1721

  
  

  QMRO: qmroHref
• Tan WS, Bellan M, Nerviani A et al. (2015). OP0208 Synovial Immunopathology Defines Clinical Responsiveness to Dmard Therapy in Early Psoriatic Arthritis: A Pre- and Post-Treatment Mechanistic Study Using a Minimally Invasive Ultrasound-Guided Synovial Biopsy Procedure. nameOfConference

  
  

  DOI: 10.1136/annrheumdis-2015-eular.3182

  
  

  QMRO: qmroHref
• Nerviani A, Humby F, Kelly S et al. (2015). THU0033 A Functional Inhibitory Role for the GAS6/MERTK Axis in Modulating Synovial Inflammation in Rheumatoid Arthritis. nameOfConference

  
  

  DOI: 10.1136/annrheumdis-2015-eular.5727

  
  

  QMRO: qmroHref
• Di Cicco M, Humby F, Kelly S et al. (2015). Young Investigator AwadrI32. Synovial Pathotype Predicts Response to TNF-Alpha Inhibitors In Patients With Rheumatoid Arthritis. nameOfConference

  
  

  DOI: 10.1093/rheumatology/kev046.006

  
  

  QMRO: qmroHref
• Di Cicco M, Humby F, Kelly S et al. (2015). SYNOVIAL PATHOTYPE PREDICTS RESPONSE TO TNF-ALPHA INHIBITORS IN PATIENTS WITH RHEUMATOID ARTHRITIS. nameOfConference

  
  

  DOI: doi

  
  

  QMRO: qmroHref
• Astorri E, Nerviani A, Bombardieri M et al. (2015). Towards a stratified targeted approach with biologic treatments in rheumatoid arthritis: role of synovial pathobiology.. nameOfConference

  
  

  DOI: 10.2174/1381612821666150310145758

  
  

  QMRO: qmroHref
• Di Cicco M, Kelly S, Humby F et al. (2014). SAT0048 Synovial Lymphocytic Aggregates Predict Clinical Response to Certolizumab Pegol in Rheumatoid Arthritis (Clinical and Pathological Response to Certolizumab-Pegol (Clip-Cert) Study). nameOfConference

  
  

  DOI: 10.1136/annrheumdis-2014-eular.5564

  
  

  QMRO: qmroHref
• Di Cicco M, Kelly S, Humby F et al. (2014). 101. Synovial Ectopic Lymphoneogenesis Predicts Primary Clinical Response to Certolizumab Pegol in Patients with Rheumatoid Arthritis. nameOfConference

  
  

  DOI: 10.1093/rheumatology/keu101.022

  
  

  QMRO: qmroHref
• Sola D, Sainaghi PP, Coccetta A et al. (2013). AB0228 Gas6/tam-system in systemic sclerosis and sjÖgren syndrome: SMER as an indicator of pulmonary hypertension. nameOfConference

  
  

  DOI: 10.1136/annrheumdis-2012-eular.228

  
  

  QMRO: qmroHref
• Sola D, Nerviani A, Molinari R et al. (2013). AB0346 Safety and efficacy of rheumatoid arthritis treatment with modified-release prednisone (mr-pdn), experience in “real life”.. nameOfConference

  
  

  DOI: 10.1136/annrheumdis-2013-eular.2668

  
  

  QMRO: qmroHref
• Nerviani A, Cerutti C, Molinari R et al. (2013). AB0923 Subclinical entheseal involvement in patients with psoriasis: A case-control ultrasound study. nameOfConference

  
  

  DOI: 10.1136/annrheumdis-2012-eular.923

  
  

  QMRO: qmroHref
• Di Cicco M, Kelly S, Humby F et al. (2014). SYNOVIAL ECTOPIC LYMPHONEOGENESIS PREDICTS PRIMARY CLINICAL RESPONSE TO CERTOLIZUMAB PEGOL IN PATIENTS WITH RHEUMATOID ARTHRITIS. nameOfConference

  
  

  DOI: doi

  
  

  QMRO: qmroHref
• Sola D, Sainaghi PP, Coccetta A et al. (2013). Gas6/tam-system in systemic sclerosis and sjogren syndrome: SMER as an indicator of pulmonary hypertension. nameOfConference

  
  

  DOI: doi

  
  

  QMRO: qmroHref
• Sola D, Nerviani A, Molinari R et al. (2013). SAFETY AND EFFICACY OF RHEUMATOID ARTHRITIS TREATMENT WITH MODIFIED-RELEASE PREDNISONE (MR-PDN), EXPERIENCE IN "REAL LIFE". nameOfConference

  
  

  DOI: doi

  
  

  QMRO: qmroHref
• Di Cicco M, Kelly S, Humby F et al. (2013). Synovial Ectopic Lymphoneogenesis Predicts Clinical Response To Certolizumab Pegol In Patients With Rheumatoid Arthritis. nameOfConference

  
  

  DOI: doi

  
  

  QMRO: qmroHref
• Sainaghi PP, Bellan M, Nerviani A et al. (2013). Superiority of a High Loading Dose of Cholecalciferol to Correct Hypovitaminosis D in Patients with Inflammatory/Autoimmune Rheumatic Diseases. nameOfConference

  
  

  DOI: 10.3899/jrheum.120536

  
  

  QMRO: qmroHref
• Sainaghi PP, Bellan M, Carda S et al. (2012). Hypovitaminosis D and response to cholecalciferol supplementation in patients with autoimmune and non-autoimmune rheumatic diseases. nameOfConference

  
  

  DOI: 10.1007/s00296-011-2170-x

  
  

  QMRO: qmroHref