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Dr Elena Pontarini

Elena

Lecturer in Immunology

Centre: Experimental Medicine and Rheumatology

Email: elena.pontarini@qmul.ac.uk
Twitter: @@TheRealARGOsLab

Profile

ORCID ID: 0000-0003-0439-0344

Elena Pontarini trained as a Biomedical Scientist at the University of Udine (Italy) before securing a fellowship from the Italian Society for Cancer Research to pursue an international PhD program in the field of Immunology and Autoimmune Diseases at the Humanitas Research Institute (Milan, Italy). During her PhD, she built a broad knowledge on rheumatic autoimmune conditions, with a specific focus in Sjogren’s syndrome, as she investigated the role of NK cells in an in vivo model for salivary gland immunopathology.

In 2016, she joined Prof. Bombardieri’s group at the Centre for Experimental Medicine and Rheumatology of the William Harvey Research Institute (WHRI) as a post-doctoral research fellow. She consolidated her research interest in Sjogren’s syndrome with the award of a Versus Arthritis Foundation Fellowship, with a research project examining the immunological changes occurring during the formation of ectopic lymphoid structures in the target organs of Sjogren’s (salivary glands) and rheumatoid arthritis (synovium).

In 2020, she was appointed Lecturer in immunology at the William Harvey Research Institute.

Her current research interest is focused on investigating the relevance of specific T cell subsets (T follicular helper cells and T peripheral helper cells) in the regulation of ectopic lymphoid structures forming in the target tissue of autoimmune diseases and their role in promoting B cell lymphomagenesis. Also, these cell subsets are being explored as therapeutic targets of immunomodulatory agents in collaboration with international partners within a large EU IMI-funded Consortium for Sjogren’s Syndrome (NECESSITY). 

Awards/Grants

  • Barts Charity - Seed Grant for research (2021)
  • EULAR- Scientific training grant for young fellows (2021)
  • Versus Arthritis- Foundation Fellowship (2018-2021)
  • European Federation of Immunological Societies (EFIS)- Travel Fellowship (2013)
  • European Molecular Biology Organization (EMBO)- Travel Fellowship (2013)
  • Italian Society of Cytometry - Cytometry in experimental thesis award (2012)

Research

Group members

Farzana Chowdhury (PhD student), Aseel Atef S Ismail (PhD student).

Summary

The research focus is to understand which T cell populations can provide help to B-cell activation in the salivary glands of Sjogren’s Syndrome patients, recognised as one of the events supporting the formation of ectopic lymphoid structures. These structures are the niches of proliferating autoreactive B-cells favouring progression towards B-cell mucosa associated lymphoid tissue lymphoma. The identification of the specific T-cell population that can provide help to B-cells within Sjogren’s syndrome salivary gland will allow optimising the therapeutic targeting of the B cell-T helper cell interaction.  

In 2020, Elena published the discovery of T follicular helper (Tfh) cells and T peripheral helper (Tph) cells enriched in the blood and salivary glands of patients with Sjogren’s syndrome (Pontarini et al. ARD 2020). Tfh and Tph cells showed to be remarkably effective in promoting B cell activation, thus are likely to favour the progression towards lymphoma and may affect the clinical response to novel therapeutics targeting B/T cell interactions recently tested in clinical trials.  

Ongoing projects include the identification of the mechanisms by which Tph cells support B cell proliferation and clonal expansion and the validation of Tph cell expansion as a biomarker of disease activity and response/resistance to treatment targeting B-T co-stimulation in clinical trials. The research approach combines in vivo studies in salivary gland immunopathology animal model and the analysis of Sjogren’s syndrome patient cohorts with high dimensional flow-cytometry, histology and transcriptomic.

Elena teaches the BSc module Translational Pharmacology and Innovative Therapeutics (BMD375). 

Publications

  • Emmerich K, Calcaterra F, Tang X et al. (2024). Protocol for differentiation of monocytes and macrophages from human induced pluripotent stem cells. nameOfConference


  • Ruscitti P, Allanore Y, Baldini C et al. (2024). Tailoring the treatment of inflammatory rheumatic diseases by a better stratification and characterization of the clinical patient heterogeneity. Findings from a systematic literature review and experts' consensus. nameOfConference


  • Simoncelli E, Colafrancesco S, Pontarini E et al. (2024). AB0801 GLYCOLYSIS EXPRESSION IN LYMPHOCYTES INFILTRATING SJOGREN’S DISEASE SALIVARY GLANDS. A PRELIMINARY ANALYSIS ON THE EXPRESSION OF THE GLUCOSE TRANSPORTER GLUT-1. Scientific Abstracts


    QMRO: qmroHref
  • Pontarini E, Sciacca E, Cavallaro G et al. (2024). AB0809 USER-FRIENDLY TOOL FOR EXPLORING RNA-SEQUENCE AND BIOMARKER DISCOVERY IN SJOGREN’S DISEASE: ANALYSE THE TWO BIGGEST DATASETS OF BLOOD AND SALIVARY GLAND RNA-SEQUENCING DATA USING R SHINY APPS. Scientific Abstracts


    QMRO: qmroHref
  • Rasmussen A, Radziszewski M, Khatri B et al. (2024). OP0113 GENOME-WIDE ASSOCIATION STUDY OF Ro/SSA+ AND Ro/SSA-SJÖGREN’S CASES IN THE SJÖGREN’S GENETIC NETWORK (SGENE) DEMONSTRATES DIVERGENT GENETIC ARCHITECTURE IN PATIENT SUBPHENOTYPES. Scientific Abstracts


    QMRO: qmroHref
  • Radziszewski M, Wiley MM, Khatri B et al. (2024). OP0141 EXPLORING REGULATORY DYNAMICS: FUNCTIONAL SNPS IN THE PRDM1-ATG5 LOCUS IMPLICATED IN SYSTEMIC LUPUS ERYTHEMATOSUS AND SJÖGREN’S DISEASE. Scientific Abstracts


    QMRO: qmroHref
  • Surace A, Overend L, Sciacca E et al. (2024). OP0242 SYNOVIAL TISSUE AND BLOOD DEEP B/T CELL PHENOTYPING EXPLAINS RESPONSE MECHANISMS TO RITUXIMAB IN RHEUMATOID ARTHRITIS IN R4RA. Scientific Abstracts


    QMRO: qmroHref
  • Corsiero E, Caliste M, Pontarini E et al. (2024). POS0250 GENERATION AND VALIDATION OF A HUMAN IMMUNE scFv LIBRARY FROM SJÖGREN’S SYNDROME SALIVARY GLAND B-CELLS. Scientific Abstracts


    QMRO: qmroHref
  • Pontarini E, Rizzo MT, Liefers SC et al. (2024). POS0265 ESTABLISHING CONSISTENCY IN THE DIGITAL IMAGING ANALYSIS OF HISTOLOGICAL PARAMETERS IN SJOGREN’S DISEASE. Scientific Abstracts


    QMRO: qmroHref
  • Colafrancesco S, Simoncelli E, Pontarini E et al. (2024). POS0997 INFLAMMATION IN SJӦGREN DISEASE INDUCES SALIVARY GLAND EPITHELIAL CELLS (SGECS) METABOLIC REPROGRAMMING: FOCUS ON GLYCOLYSIS AND ITS REGULATION OF EPITHELIAL CELL ACTIVATION. Scientific Abstracts


    QMRO: qmroHref
  • Mauro D, Lin X, Pontarini E et al. (2024). CD8+ tissue-resident memory T cells are expanded in primary Sjögren’s disease and can be therapeutically targeted by CD103 blockade. nameOfConference


  • Nerviani A, Boutet M-A, Ghirardi GM et al. (publicationYear). Axl and MerTK regulate synovial inflammation and are modulated by IL-6 inhibition in rheumatoid arthritis. nameOfConference


  • Pontarini E, Sciacca E, Chowdhury F et al. (2024). Serum and Tissue Biomarkers Associated With Composite of Relevant Endpoints for Sjögren Syndrome (CRESS) and Sjögren Tool for Assessing Response (STAR) to B Cell–Targeted Therapy in the Trial of Anti–B Cell Therapy in Patients With Primary Sjögren Syndrome (TRACTISS). nameOfConference


  • Duquesne J, Basseto L, Barnes M et al. (2023). Un modèle d’intelligence artificielle prédit le focus score et le diagnostic de la maladie de Sjögren à partir de biopsies de glandes salivaires. nameOfConference


    QMRO: qmroHref
  • Chen G, Calcaterra F, Ma Y et al. (2023). Derived myeloid lineage induced pluripotent stem as a platform to study human C-C chemokine receptor type 5Δ32 homozygotes. nameOfConference


  • Pitsillidou C, Muradore I, Pontarini E et al. (2023). A redox-based characterization of human immune cell subsets by polychromatic flow cytometry. nameOfConference


  • Pontarini E, Lucchesi D, Goldmann K et al. (2023). POS0292 TRANSCRIPTOMIC PROFILING OF SJOGREN’S SALIVARY GLANDS IDENTIFIES FOLLICULAR AND EXTRA-FOLLICULAR GENE SIGNATURES ASSOCIATED WITH RHEUMATOID FACTOR SEROPOSITIVITY. nameOfConference


    QMRO: qmroHref
  • Fanti S, Stephenson E, Rocha-Vieira E et al. (2022). Circulating c-Met–Expressing Memory T Cells Define Cardiac Autoimmunity. nameOfConference


  • Nayar S, Pontarini E, Campos J et al. (publicationYear). Immunofibroblasts regulate LTα3 expression in tertiary lymphoid structures in a pathway dependent on ICOS/ICOSL interaction. nameOfConference


  • Pontarini E, Coleby R, Bombardieri M (2021). Cellular and molecular diversity in Sjogren’s syndrome salivary glands: Towards a better definition of disease subsets. nameOfConference


  • de Wolff L, Arends S, Pontarini E et al. (2021). Development and performance of the Clinical Trials ESSDAI (ClinTrialsESSDAI), consisting of frequently active clinical domains, in two randomised controlled trials in primary Sjögren's syndrome.. nameOfConference


  • Coleby R, Lucchesi D, Pontarini E et al. (2021). Stepwise changes in the murine salivary gland immune response during virally-induced ectopic lymphoid structure formation.. nameOfConference


  • Pontarini E, Chowdhury F, Sciacca E et al. (2021). OP0136 RITUXIMAB PREVENTS THE PROGRESSION OF B-CELL DRIVEN INFLAMMATORY INFILTRATE IN THE MINOR SALIVARY GLANDS OF PRIMARY SJOGREN’S SYNDROME BY DOWNREGULATING IMMUNOLOGICAL PATHWAYS KEY IN ECTOPIC GERMINAL CENTRE ORGANIZATION: RESULTS FROM THE TRACTISS TRIAL. nameOfConference


  • Pontarini E, Sciacca E, Grigoriadou S et al. (publicationYear). NKp30 Receptor Upregulation in Salivary Glands of Sjögren’s Syndrome Characterizes Ectopic Lymphoid Structures and Is Restricted by Rituximab Treatment. nameOfConference


  • Arends S, de Wolff L, van Nimwegen JF et al. (2021). Composite of Relevant Endpoints for Sjögren's Syndrome (CRESS): development and validation of a novel outcome measure. nameOfConference


  • Rivellese F, Pontarini E, Fossati-Jimack L et al. (2021). OP0011 INTEGRATION OF FLOW AND DIGITAL CYTOMETRY IN EARLY TREATMENT-NAÏVE RHEUMATOID ARTHRITIS IDENTIFIES DISTINCT IMMUNOPHENOTYPES IN PERIPHERAL BLOOD AND DISEASE TISSUE. nameOfConference


  • Arends S, de Wolff L, Van Nimwegen JF et al. (2021). OP0130 COMPOSITE OF RELEVANT ENDPOINTS IN SJÖGREN’S SYNDROME (CRESS): A COMPREHENSIVE TOOL FOR CLINICAL TRIALS. nameOfConference


  • de Wolff L, Arends S, Pontarini E et al. (2021). Performance of the Clinical Trials ESSDAI (ClinTrialsESSDAI), an Adjusted ESSDAI Score, in Two Randomised Clinical Trials in Patients with Primary Sjogren's Syndrome. nameOfConference

    DOI: doi

  • Jimenez-Royo P, Bombardieri M, Ciurtin C et al. (2021). Advanced imaging for quantification of abnormalities in the salivary glands of patients with primary Sjögren’s syndrome. nameOfConference


  • Pontarini E, Verstappen GM, Grigoriadou S et al. (2020). Blocking T cell co-stimulation in primary Sjögren's syndrome: rationale, clinical efficacy and modulation of peripheral and salivary gland biomarkers.. nameOfConference

    DOI: doi

  • Bombardieri M, Argyropoulou OD, Ferro F et al. (2020). One year in review 2020: pathogenesis of primary Sjögren's syndrome.. nameOfConference

    DOI: doi

  • Lucchesi D, Pontarini E, Donati V et al. (2020). The use of digital image analysis in the histological assessment of Sjögren's syndrome salivary glands improves inter-rater agreement and facilitates multicentre data harmonisation.. nameOfConference

    DOI: doi

  • Pontarini E, Murray-Brown WJ, Croia C et al. (2020). Unique expansion of IL-21+ Tfh and Tph cells under control of ICOS identifies Sjögren’s syndrome with ectopic germinal centres and MALT lymphoma. nameOfConference


  • Lucchesi D, Coleby R, Pontarini E et al. (2020). Impaired Interleukin‐27–Mediated Control of CD4+ T Cell Function Impact on Ectopic Lymphoid Structure Formation in Patients With Sjögren's Syndrome. nameOfConference


  • Rivellese F, Pontarini E, Pitzalis C (2020). Tertiary Lymphoid Organs in Rheumatoid Arthritis.. nameOfConference


  • Lucchesi D, Coleby R, Pontarini E et al. (2020). O31 IL-27 regulates the magnitude of ectopic germinal centres in experimental sialadenitis but fails to modulate IL-17 and IFNg production in CD4 T cells from patients with Sjögren's syndrome. nameOfConference


  • Pontarini E, Verstappen GM, Grigoriadou S et al. (2020). Blocking T cell co-stimulation in primary Sjogren's syndrome: rationale, clinical efficacy and modulation of peripheral and salivary gland biomarkers. nameOfConference

    DOI: doi

    QMRO: qmroHref
  • Lucchesi D, Coleby R, Pontarini E et al. (2020). IL-27 REGULATES THE MAGNITUDE OF ECTOPIC GERMINAL CENTRES IN EXPERIMENTAL SIALADENITIS BUT FAILS TO MODULATE IL-17 AND IFNG PRODUCTION IN CD4 T CELLS FROM PATIENTS WITH SJOGREN'S SYNDROME. nameOfConference

    DOI: doi

  • Bombardieri M, Argyropoulou OD, Ferro F et al. (2020). One year in review 2020: pathogenesis of primary Sjogren's syndrome. nameOfConference

    DOI: doi

  • Lucchesi D, Pontarini E, Donati V et al. (2020). The use of digital image analysis in the histological assessment of Sjogren's syndrome salivary glands improves inter-rater agreement and facilitates multicentre data harmonisation. nameOfConference

    DOI: doi

  • Pucino V, Certo M, Bulusu V et al. (2019). Lactate Buildup at the Site of Chronic Inflammation Promotes Disease by Inducing CD4+ T Cell Metabolic Rewiring. nameOfConference


  • Grigoriadou S, Chowdhury F, Pontarini E et al. (2019). B-cell depletion with rituximab in the treatment of primary Sjögren's syndrome: What have we learnt?. nameOfConference

    DOI: doi

  • Colafrancesco S, Priori R, Smith CG et al. (2020). CXCL13 as biomarker for histological involvement in Sjögren’s syndrome. nameOfConference


    QMRO: qmroHref
  • Lucchesi D, Coleby R, Pontarini E et al. (2019). OP0276 DENDRITIC CELL-DERIVED IL-27 REGULATES THE MAGNITUDE OF INDUCIBLE ECTOPIC GERMINAL CENTRES BUT FAILS TO DOWNMODULATE IL-17 PRODUCTION IN CD4 T CELLS FROM PATIENTS WITH SJÖGREN’S SYNDROME. Oral Presentations


  • Pontarini E, Brown WM, Croia C et al. (2019). OP0279 A UNIQUE IL-21 SIGNATURE CHARACTERIZES LESIONAL AND CIRCULATING T-FOLLICULAR HELPER CELLS IN SJÖGREN’S SYNDROME PATIENTS WITH ECTOPIC GERMINAL CENTRES AND MALT LYMPHOMA. Oral Presentations


  • Rivellese F, Manou-Stathopoulou S, Mauro D et al. (2019). THU0234 THE TRANSCRIPTION FACTORS IKAROS (IKZF1) AND AIOLOS (IKZF3) ARE EXPRESSED IN THE SALIVARY GLANDS OF SJÖGREN’S SYNDROME PATIENTS WITH LYMPHOID AGGREGATES AND MODULATE B CELL ACTIVATION IN VITRO. Poster Presentations


  • Nocturne G, Pontarini E, Bombardieri M et al. (2021). Lymphomas complicating primary Sjögren's syndrome: from autoimmunity to lymphoma.. nameOfConference


  • Grigoriadou S, Chowdhury F, Pontarini E et al. (2019). B-cell depletion with rituximab in the treatment of primary Sjogren's syndrome: what have we learnt?. nameOfConference

    DOI: doi

  • Prediletto E, Pontarini E, Lucchesi D et al. (2019). Synovial fluid fibroblast-like synoviocytes enhance long-term survival of EBV infected memory B cells in rheumatoid arthritis. nameOfConference

    DOI: doi

    QMRO: qmroHref
  • Pontarini E, Lucchesi D, Fossati-Jimack L et al. (2019). NK cell recruitment in salivary glands provides early viral control but is dispensable for tertiary lymphoid structure formation. nameOfConference


  • Notarstefano C, Croia C, Pontarini E et al. (2018). A clinical and histopathological analysis of the anti-centromere antibody positive subset of primary Sjögren's syndrome.. nameOfConference

    DOI: doi

  • Mauro D, Tsang V, Lucey-Clayton I et al. (2018). FRI0271 Dimethyl fumarate inhibits ube2l3 mediated tlr7 signalling and autoreactive b cell development in sle. FRIDAY, 15 JUNE 2018


  • Pontarini E, Lucchesi D, Bombardieri M (2018). Current Views on the Pathogenesis of Sjögren's Syndrome. nameOfConference


    QMRO: qmroHref
  • Pontarini E, Lucchesi D, Bombardieri M (2018). Current views on the pathogenesis of Sjögren's syndrome. nameOfConference


  • Lucchesi D, Pontarini E, Coleby R et al. (2018). P079 Interleukin-27 regulates the magnitude of the ectopic germinal centre response in a viral-inducible model of sialadenitis. Poster presentations


    QMRO: qmroHref
  • Notarstefano C, Croia C, Pontarini E et al. (2018). A clinical and histopathological analysis of the anti-centromere antibody positive subset of primary Sjogren's syndrome. nameOfConference

    DOI: doi

  • Rivellese F, Mauro D, Congia M et al. (2018). Expression and Functions of the Transcription Factors Ikaros and Aiolos in Sjogren's Syndrome and Systemic Lupus Erythematosus. nameOfConference

    DOI: doi

  • Lucchesi D, Pontarini E, Coleby R et al. (2018). Interleukin-27 regulates the magnitude of the ectopic germinal centre response in a virus-induced murine model of sialadenitis. nameOfConference

    DOI: doi

    QMRO: qmroHref
  • Corsiero E, Jagemann L, Pontarini E et al. (2018). Single-cell VH and VL Ig gene analysis reveal clonal relationship between IgM plus neoplastic B cells and plasmablasts in SS patients with parotid MALT lymphoma. nameOfConference

    DOI: doi

    QMRO: qmroHref
  • Pontarini E, Murray-Brown W, Croia C et al. (2018). T follicular-helper cells (TFH) enrichment and follicular T regulatory cells (TFR) exclusion from ectopic germinal centers in salivary glands of Sjogren's Syndrome patients. nameOfConference

    DOI: doi

  • Pontarini E, Murray-Brown W, Croia C et al. (2017). OP0300 Enrichment of T follicular-helper cells (TFH) and exclusion of t follicular-regulatory cells (TFR) from ectoPIC germinal centers in salivary glands of sjogren's syndrome patients. Oral Presentations


  • Lucchesi D, Pontarini E, Pitzalis C et al. (2017). MYELOID CELLS DRIVE EARLY INFLAMMATION AND ORCHESTRATE SALIVARY GLANDS TERTIARY LYMPHOID STRUCTURES FORMATION IN A MODEL OF INDUCIBLE SIALADENITIS. EWRR


    QMRO: qmroHref
  • Calcaterra F, Pontarini E, Guibin C et al. (2017). Development of iPSC-derived monocytes/macrophages: a new reliable tool to study rare diseases and for drug screening. nameOfConference

    DOI: doi

    QMRO: qmroHref
  • Mauro D, Tsang V, Clayton-Lucey IA et al. (2017). Regulation of TLR7 Signalling By UBE2L3 Dependent Linear Ubiquitination Explains Dimethyl Fumarate Suppression of Autoreactive B Cell Development in SLE. nameOfConference

    DOI: doi

  • Pontarini E, Brown WM, Croia C et al. (2017). T Follicular- Helper CELLS (TFH) Enrichment and T Follicular-Regulatory CELLS (TFR) Exclusion from Ectopic Germinal Centers in Salivary Glands of Sjogren's Syndrome Patients. nameOfConference

    DOI: doi

  • Hudspeth K, Donadon M, Cimino M et al. (2016). Human liver-resident CD56bright/CD16neg NK cells are retained within hepatic sinusoids via the engagement of CCR5 and CXCR6 pathways. nameOfConference


    QMRO: qmroHref
  • Pontarini E, Lucchesi D, Mavilio D et al. (2015). AB0169 Recruitment and Activation of NK Cells in the Salivary Glands Regulates Early Viral Control but is Dependable for Autoimmunity and Focal Lymphocytic Sialoadenitis in an Inducible Murine Model of Sjogren-Like Disease. nameOfConference


    QMRO: qmroHref
  • Pontarini E, Fabris M, Quartuccio L et al. (2015). Treatment with belimumab restores B cell subsets and their expression of B cell activating factor receptor in patients with primary Sjogren’s syndrome. nameOfConference


    QMRO: qmroHref
  • Pontarini E, Lucchesi D, Mavilio D et al. (2015). Recruitment and Activation of NK Cells in the Salivary Glands Regulates Early Viral Control but is Dependable for Autoimmunity and Focal Lymphocytic Sialoadenitis in an Inducible Murine Model of Sjogren-Like Disease. nameOfConference

    DOI: doi

    QMRO: qmroHref
  • Mikulak J, Bozzo L, Roberto A et al. (2014). Dopamine Inhibits the Effector Functions of Activated NK Cells via the Upregulation of the D5 Receptor. nameOfConference


    QMRO: qmroHref
  • Rusmini M, Griseri P, Matera I et al. (2014). Expression Variability and Function of the RET Gene in Adult Peripheral Blood Mononuclear Cells. nameOfConference


    QMRO: qmroHref
  • Fabris M, Quartuccio L, Pontarini E et al. (2013). AB0311 The 158vv fcgamma receptor iiia genotype predicts a positive response to rituximab in rheumatoid arthritis: Analysis in a large cohort of italian patients. nameOfConference


    QMRO: qmroHref
  • Quartuccio L, Maset M, De Maglio G et al. (2013). AB0760 Role of oral cyclophosphamide in the treatment of giant cell arteritis. nameOfConference


    QMRO: qmroHref
  • Quartuccio L, Fabris M, Pontarini E et al. (2013). FRI0255 The 158vv fcgamma receptor 3a genotype is associated with response to rituximab in rheumatoid arthritis: results of an italian multicentre study. nameOfConference


    QMRO: qmroHref
  • Quartuccio L, Salvin S, Fabris M et al. (2013). SAT0205 Blys up-regulation and salivary clonal B-cell expansion characterize sjögren’s syndrome-related lymphoproliferative disorders and correlate with the new ESSDAI score. nameOfConference


    QMRO: qmroHref
  • Fabris M, Dolcetti R, Pasini E et al. (2014). High prevalence of Chlamydophila psittaci subclinical infection in Italian patients with Sjögren's syndrome and parotid gland marginal zone B-cell lymphoma of MALT-type.. nameOfConference

    DOI: doi

    QMRO: qmroHref
  • Lucchesi D, Pontarini E, Pitzalis C et al. (2014). Innate immune system early activation precedes the formation of functional tertiary lymphoid structures in a novel model of salivary gland ectopic lymphoid neogenesis. nameOfConference

    DOI: doi

    QMRO: qmroHref
  • Pontarini E, Lucchesi D, Bombardieri M et al. (2014). Recruitment and activation of NK cells regulates early immune responses to viral infection in the salivary glands of an inducible murine model of Sjogren-like disease. nameOfConference

    DOI: doi

    QMRO: qmroHref
  • Hudspeth K, Pontarini E, Tentorio P et al. (2013). The role of natural killer cells in autoimmune liver disease: A comprehensive review. nameOfConference


    QMRO: qmroHref
  • Fabris M, Dolcetti R, Pasini E et al. (2013). High prevalence of Chlamydophila Psittaci subclinical infection in Italian patients with Sjögren's syndrome and parotid gland B‐cell lymphoma.. nameOfConference


    QMRO: qmroHref
  • Quartuccio L, Fabris M, Pontarini E et al. (2014). The 158VV Fcgamma receptor 3A genotype is associated with response to rituximab in rheumatoid arthritis: results of an Italian multicentre study. nameOfConference


    QMRO: qmroHref
  • Quartuccio L, Fabris M, Pontarini E et al. (2013). THE 158VV FCGAMMA RECEPTOR 3A GENOTYPE IS ASSOCIATED WITH RESPONSE TO RITUXIMAB IN RHEUMATOID ARTHRITIS: RESULTS OF AN ITALIAN MULTICENTRE STUDY. nameOfConference

    DOI: doi

    QMRO: qmroHref
  • Fabris M, Quartuccio L, Vital E et al. (2013). The TTTT B lymphocyte stimulator promoter haplotype is associated with good response to rituximab therapy in seropositive rheumatoid arthritis resistant to tumor necrosis factor blockers. nameOfConference


    QMRO: qmroHref
  • Stinco G, Fabris M, Pasini E et al. (2012). Detection of DNA of Chlamydophila psittaci in subjects with psoriasis: a casual or a causal link?. nameOfConference


    QMRO: qmroHref
  • Quartuccio L, Salvin S, Fabris M et al. (2013). BLyS upregulation in Sjögren’s syndrome associated with lymphoproliferative disorders, higher ESSDAI score and B-cell clonal expansion in the salivary glands. nameOfConference


    QMRO: qmroHref
  • Quartuccio L, Maset M, De Maglio G et al. (2012). Role of oral cyclophosphamide in the treatment of giant cell arteritis. nameOfConference


    QMRO: qmroHref
  • Fabris M, De Vita S, Pasini E et al. (2011). Chlamydophila psittaci subclinical infection in chronic polyarthritis.. nameOfConference

    DOI: doi

    QMRO: qmroHref
  • Ceccarelli F, Perricone C, Fabris M et al. (2011). Transforming growth factor β 869C/T and interleukin 6 -174G/C polymorphisms relate to the severity and progression of bone-erosive damage detected by ultrasound in rheumatoid arthritis. nameOfConference


    QMRO: qmroHref
  • Fabris M, Quartuccio L, Lombardi S et al. (2010). Study on the possible role of the -174G>C IL-6 promoter polymorphism in predicting response to rituximab in rheumatoid arthritis. nameOfConference


    QMRO: qmroHref
  • Quartuccio L, Fabris M, Maset M et al. (2011). BONE MARROW B-CELL CLONAL EXPANSION IN MIXED CRYOGLOBULINEMIA: ASSOCIATION WITH NEPHRITIS AND SWITCH INTO A POLYCLONAL PATTERN AFTER B-CELL DEPLETION. nameOfConference

    DOI: doi

    QMRO: qmroHref
  • Fabris M, De Vita S, Blasone N et al. (2010). Serum levels of anti-CCP antibodies, anti-MCV antibodies and RF IgA in the follow-up of patients with rheumatoid arthritis treated with rituximab. nameOfConference


    QMRO: qmroHref
  • Fabris M, Quartuccio L, Lombardi S et al. (2012). The CC homozygosis of the −174G>C IL-6 polymorphism predicts a lower efficacy of rituximab therapy in rheumatoid arthritis. nameOfConference


    QMRO: qmroHref
  • Fabris M, Panighel C, Blasone N et al. (2010). BLyS Role in the Diagnosis and Prognosis of Neuroendocrine Tumors: Preliminary Results.. nameOfConference

    DOI: doi

    QMRO: qmroHref

Sponsors

  • Barts Charity - Seed Grant for research (2021)
  • EULAR - Scientific training grant for young fellows (2021)
  • Versus Arthritis - Foundation Fellowship (2018-2021)
  • European Federation of Immunological Societies (EFIS) - Travel Fellowship (2013)
  • European Molecular Biology Organization (EMBO) - Travel Fellowship (2013)

Collaborators

  • Dr Gwenny Verstappen - University of Groningen
  • Dr Silvia della Bella - University of Milan
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