Dr Bernard North, BSc, MSc (Eng), PhD

Profile

I currently serve as senior statistician at the CRUK Cancer Prevention Trials Unit (CPTU) where I am the independent statistician on a number of CPTU trials in cancer prevention and early detection. I also manage 3 other statisticians, have been second supervisor on a PhD at our previous college (KCL), have sat on trial committees and contribute to other relevant statistical projects. 

Research

Research Interests:

I am interested in statistical aspects of clinical trials particularly in oncology largely related to our work in cancer prevention. I am also interested in clinical prediction models, their development and validation and use of biomarkers.

Publications

• Kelsell DP, Norgett EE, Unsworth H et al. (2005). Mutations in ABCA12 underlie the severe congenital skin disease harlequin ichthyosis..

  
  

  DOI: 10.1086/429844

  
  

  QMRO:
• North BV, Curtis D, Sham PC (2005). Application of logistic regression to case-control association studies involving two causative loci.

  
  

  DOI: 10.1159/000085222

  
  

  QMRO:
• Allotey RA, Mohan V, McDermott MF et al. (2004). The EIF2AK3 gene region and type I diabetes in subjects from South India..

  
  

  DOI: 10.1038/sj.gene.6364139

  
  

  QMRO:
• Jackson AE, Cassell PG, North BV et al. (2004). Polymorphic variations in the neurogenic differentiation-1, neurogenin-3, and hepatocyte nuclear factor-1alpha genes contribute to glucose intolerance in a South Indian population..

  
  

  DOI: 10.2337/diabetes.53.8.2122

  
  

  QMRO:
• Sham PC, Rijsdijk FV, Knight J et al. (2004). Haplotype association analysis of discrete and continuous traits using mixture of regression models.

  
  

  DOI: 10.1023/B:BEGE.0000013734.39266.a3

  
  

  QMRO:
• North BV, Curtis D, Cassell PG et al. (2003). Assessing optimal neural network architecture for identifying disease-associated multi-marker genotypes using a permutation test, and application to calpain 10 polymorphisms associated with diabetes..

  
  

  DOI: 10.1046/j.1469-1809.2003.00030.x

  
  

  QMRO:
• Ogunkolade B-W, Boucher BJ, Prahl JM et al. (2002). Vitamin D receptor (VDR) mRNA and VDR protein levels in relation to vitamin D status, insulin secretory capacity, and VDR genotype in Bangladeshi Asians..

  
  

  DOI: 10.2337/diabetes.51.7.2294

  
  

  QMRO:
• Cassell PG, Jackson AE, North BV et al. (2002). Haplotype combinations of calpain 10 gene polymorphisms associate with increased risk of impaired glucose tolerance and type 2 diabetes in South Indians..

  
  

  DOI: 10.2337/diabetes.51.5.1622

  
  

  QMRO:
• Chowdhury ZM, McDermott MF, Davey S et al. (2002). Genetic susceptibility to fibrocalculous pancreatic diabetes in Bangladeshi subjects: a family study.

  
  

  DOI: 10.1038/sj/gene/6363814

  
  

  QMRO:
• Barakat K, Kennon S, Hitman GA et al. (2001). Interaction between smoking and the glycoprotein IIIa Pl(A2) polymorphism in non-ST-elevation acute coronary syndromes.

  
  

  DOI: 10.1016/S0735-1097(01)01610-2

  
  

  QMRO: