Each seminar has a featured speaker(s) and theme and there will be an opportunity to connect and ask about their work.
Staff and students from Queen Mary and Barts Health NHS Trust are invited to join us, to:
Presentation by Anna Schultze (London School of Hygiene and Tropical Medicine). Transparency in epidemiological research is critically important, especially given the increased use of real-world evidence for regulatory decision making. Many open science resources encourage the sharing of all research materials, including data and code, to enable analyses to be independently verified and reproduced. Although data sharing is rarely possible for epidemiologists given stringent data protection, sharing code (in which the programming code used to process and analyse research data is made public) often is. The first half of this talk will introduce the rationale for sharing programming code and present some results from a recent systematic review on code sharing in pharmacoepidemiology. The second half will involve an interactive series of polls and discussion about code sharing, including potential barriers and how to overcome them.
Presentation by Dr Kevin Wing from the London School of Hygiene and Tropical Medicine, with Dr Paris Baptiste. This seminar will provide an overview of the “target trial” framework, which adds an additional layer of rigour and transparency to observational studies. We will discuss how emulating an existing randomised controlled trial in observational data can improve confidence in the results and generate evidence for patient groups that are typically underrepresented in trials. We’ll also consider the challenges that remain, including residual or unknown confounders - how can research teams know that their observational study reports a “true” effect?
With the consent of the speakers, recordings of our seminars are available to watch here after the event.
25 March 2024
15 January 2024
14 December 2023
2 November 2023
Co-chairs: Rohini Mathur, Jianhua Wu (WIPH) and Claude Chelala (BCI) Committee members: Paris Baptiste, Fabiola Eto, Harriet Larvin, Jing Hui Law, Judith Offman, Stuart Rison, Mary Thomas, Nicola Firman (WIPH)