Dr Daniel Harding

Profile

Dr Harding is a NHIR sponsored Clinical Lecturer in the Marelli-Berg laboratory at Queen Mary University of London (QMUL). He completed his chemistry and medical degrees at the University of Oxford prior to undertaking his clinical cardiology training in London. His research background includes molecular biology (Oxford, Prof C Schofield) and genetic immunology (London, Prof F Brennan). He was previously an Academic Clinical Fellow at University College London (UCL) before joining QMUL for his BHF funded PhD in cardioimmunology.

Research

Group members

Dr Harding is currently part of the Professor Marelli-Berg laboratory.

Summary

Our research focuses on the role of the immune system in inflammatory cardiovascular disease. We have a clinical interest in dilated cardiomyopathy (DCM), acute myocarditis and infective endocarditis. We are also exploring the immune response to cardiogenic shock. 

Publications

• Sikking MA, Harding D, Henkens MTHM et al. (2024). Cytotoxic T Cells Drive Outcome in Inflammatory Dilated Cardiomyopathy.

  
  

  DOI: 10.1161/circresaha.124.325183

  
  

  QMRO:
• Shyam-Sundar V, Harding D, Khan A et al. . Imaging for the diagnosis of acute myocarditis: can artificial intelligence improve diagnostic performance?.

  
  

  DOI: 10.3389/fcvm.2024.1408574

  
  

  QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/98897
• Shyam-Sundar V, Nicholls H, Harding D et al. (2024). 14 A single centre retrospective study of patients presenting with acute forms of myocarditis: insights from clinical and cardiac MRI data. ACHD/Valve disease/Pericardial disease/Cardiomyopathy

  
  

  DOI: 10.1136/heartjnl-2024-bcs.14

  
  

  QMRO:
• Papadopoulou A, Harding D, Slabaugh G et al. (2024). Prediction of atrial fibrillation and stroke using machine learning models in UK Biobank.

  
  

  DOI: 10.1016/j.heliyon.2024.e28034

  
  

  QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/95921
• Golino M, Harding D, Del Buono MG et al. (2024). Innate and adaptive immunity in acute myocarditis.

  
  

  DOI: 10.1016/j.ijcard.2024.131901

  
  

  QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/96019
• Harding D, Fanti S, Marelli-Berg F (2024). Tumour necrosis factor-α in cardiac inflammation: friend or foe?.

  
  

  DOI: 10.1093/cvr/cvad180

  
  

  QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/94929
• Harding D, Marelli-Berg F (2023). Interferon-gamma signs off an old heart.

  
  

  DOI: 10.1093/cvr/cvad151

  
  

  QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/91978
• Fanti S, Stephenson E, Rocha-Vieira E et al. (2022). Circulating c-Met–Expressing Memory T Cells Define Cardiac Autoimmunity.

  
  

  DOI: 10.1161/circulationaha.121.055610

  
  

  QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/83023
• Harding D, Chong MHA, Lahoti N et al. (2023). Dilated cardiomyopathy and chronic cardiac inflammation: Pathogenesis, diagnosis and therapy.

  
  

  DOI: 10.1111/joim.13556

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/80520
• Sotto I, Arefin R, Mouyis K et al. (2020). 65 Changes in anticoagulant use in England over two decades: 1998-2018.

  
  

  DOI: 10.1136/heartjnl-2020-bcs.65

  
  

  QMRO:

Collaborators

Internal

• Professor Federica Marelli-Berg
• Dr Suchita Nadkarni
• Dr Paula Longhi
• Dr Alastair Proudfoot
• Dr Vijay Shyam-Sundar

External
Dr Barbara Szomolay (Cardiff)

Industry
Astrazeneca 

Teaching

Dr Harding supervises undergraduate students on the BIO604 and SSC4 programmes at QMUL. He also teaches clinical cardiology to undergraduate medical students at UCL and is a OSCE examiner for QMUL.

Disclosures

No disclosures.