Dr Daniel Harding

Profile

Dr Harding is a NHIR sponsored Clinical Lecturer in the Marelli-Berg laboratory at Queen Mary University of London (QMUL). He completed his chemistry and medical degrees at the University of Oxford prior to undertaking his clinical cardiology training in London. His research background includes molecular biology (Oxford, Prof C Schofield) and genetic immunology (London, Prof F Brennan). He was previously an Academic Clinical Fellow at University College London (UCL) before joining QMUL for his BHF funded PhD in cardioimmunology.

Research

Group members

Dr Harding is currently part of the Professor Marelli-Berg laboratory.

Summary

Our research focuses on the role of the immune system in inflammatory cardiovascular disease. We have a clinical interest in dilated cardiomyopathy (DCM), acute myocarditis and infective endocarditis. We are also exploring the immune response to cardiogenic shock. 

Publications

• Sikking MA, Harding D, Henkens MTHM et al. (2024). Cytotoxic T Cells Drive Outcome in Inflammatory Dilated Cardiomyopathy. nameOfConference

  
  

  DOI: 10.1161/circresaha.124.325183

  
  

  QMRO: qmroHref
• Shyam-Sundar V, Harding D, Khan A et al. (publicationYear). Imaging for the diagnosis of acute myocarditis: can artificial intelligence improve diagnostic performance?. nameOfConference

  
  

  DOI: 10.3389/fcvm.2024.1408574

  
  

  QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/98897
• Shyam-Sundar V, Nicholls H, Harding D et al. (2024). 14 A single centre retrospective study of patients presenting with acute forms of myocarditis: insights from clinical and cardiac MRI data. ACHD/Valve disease/Pericardial disease/Cardiomyopathy

  
  

  DOI: 10.1136/heartjnl-2024-bcs.14

  
  

  QMRO: qmroHref
• Papadopoulou A, Harding D, Slabaugh G et al. (2024). Prediction of atrial fibrillation and stroke using machine learning models in UK Biobank. nameOfConference

  
  

  DOI: 10.1016/j.heliyon.2024.e28034

  
  

  QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/95921
• Golino M, Harding D, Del Buono MG et al. (2024). Innate and adaptive immunity in acute myocarditis. nameOfConference

  
  

  DOI: 10.1016/j.ijcard.2024.131901

  
  

  QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/96019
• Harding D, Fanti S, Marelli-Berg F (2024). Tumour necrosis factor-α in cardiac inflammation: friend or foe?. nameOfConference

  
  

  DOI: 10.1093/cvr/cvad180

  
  

  QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/94929
• Harding D, Marelli-Berg F (2023). Interferon-gamma signs off an old heart. nameOfConference

  
  

  DOI: 10.1093/cvr/cvad151

  
  

  QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/91978
• Fanti S, Stephenson E, Rocha-Vieira E et al. (2022). Circulating c-Met–Expressing Memory T Cells Define Cardiac Autoimmunity. nameOfConference

  
  

  DOI: 10.1161/circulationaha.121.055610

  
  

  QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/83023
• Harding D, Chong MHA, Lahoti N et al. (2023). Dilated cardiomyopathy and chronic cardiac inflammation: Pathogenesis, diagnosis and therapy. nameOfConference

  
  

  DOI: 10.1111/joim.13556

  
  

  QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/80520
• Sotto I, Arefin R, Mouyis K et al. (2020). 65 Changes in anticoagulant use in England over two decades: 1998-2018. nameOfConference

  
  

  DOI: 10.1136/heartjnl-2020-bcs.65

  
  

  QMRO: qmroHref
• Hayward C, Mouyis K, Gillott H et al. (2020). 88 National confidential enquiry into patient outcome and death in patients admitted with heart failure: a quality improvement project to improve compliance with recommendations. Heart Failure

  
  

  DOI: 10.1136/heartjnl-2020-bcs.88

  
  

  QMRO: qmroHref
• Harding D, Cahill TJ, Redwood SR et al. (2020). Infective endocarditis complicating transcatheter aortic valve implantation. nameOfConference

  
  

  DOI: 10.1136/heartjnl-2019-315338

  
  

  QMRO: qmroHref
• Hayward C, Perez C, Patel H et al. (2019). 11 The impact of misclassifying left ventricular size if indexing to body surface area is not performed. Imaging

  
  

  DOI: 10.1136/heartjnl-2019-bcs.11

  
  

  QMRO: qmroHref
• Harding D, Prendergast B (publicationYear). Advanced imaging improves the diagnosis of infective endocarditis. nameOfConference

  
  

  DOI: 10.12688/f1000research.13791.1

  
  

  QMRO: qmroHref
• Nagendran M, Harding D, Teo W et al. (2013). Poor adherence of randomised trials in surgery to CONSORT guidelines for non-pharmacological treatments (NPT): a cross-sectional study. nameOfConference

  
  

  DOI: 10.1136/bmjopen-2013-003898

  
  

  QMRO: qmroHref
• Hamed RB, Gomez-Castellanos JR, Thalhammer A et al. (2011). Stereoselective C–C bond formation catalysed by engineered carboxymethylproline synthases. nameOfConference

  
  

  DOI: 10.1038/nchem.1011

  
  

  QMRO: qmroHref

Collaborators

Internal

• Professor Federica Marelli-Berg
• Dr Suchita Nadkarni
• Dr Paula Longhi
• Dr Alastair Proudfoot
• Dr Vijay Shyam-Sundar

External
Dr Barbara Szomolay (Cardiff)

Industry
Astrazeneca 

Teaching

Dr Harding supervises undergraduate students on the BIO604 and SSC4 programmes at QMUL. He also teaches clinical cardiology to undergraduate medical students at UCL and is a OSCE examiner for QMUL.

Disclosures

No disclosures.